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Organisms are continually challenged by multiple threats in the environment, and such threats are seldom constant in either time or space. Therefore, organisms must maintain physiological, behavioural, morphological and life- history adaptations across environments to prevent reductions in fitness. Freshwater ecosystems are particularly variable environments, and so organisms inhabiting lakes and

The objective of this thesis is to investigate the synthesis of well-defined polymer nanohybrid materials bearing desirable functionality via surface-initiated atom transfer radical polymerization (SI-ATRP) for potential bioapplications.SI-ATRP is an excellent controlled radical polymerization (CRP) method for the synthesis of polymer nanohybrid by growing polymer brushes (chains) from an interfac

The current threats of climate change connected to the unsustainable consumption of fossil resources paired with an increasing world population demands the exploration of alternative raw materials for the production of food, fuel and specialty chemicals. Agricultural waste streams present suitable sources due to their availability in large quantities at low costs without competing with current foo

Smallholder farming, which is largely rainfed and relies on mostly rudimentary tools, predominates Ghana’s agricultural sector. The sector’s importance to the national economy is exemplified in not only the proportion of the active national labour force engaged in it but also in terms of its export earnings and service as a source of food for the vast majority of the population. However, the secto

A multigene phylogenetic study was carried out to test current, mostly morphology-based hypotheses on Sterrhinae phylogeny with additional material included from further geographical areas and morphologically different lineages. A maximum likelihood analysis (11 molecular markers and 7665 bp) was conducted on 76 species and 41 genera using iq-tree software. The resulting phylogenetic hypothesis is

One of the greatest challenges the world is facing is climate change. The need of reduction of energy use and an increased use of renewable energy in buildings constitutes important climate change mitigation measures.The objective of this research is to investigate methodologies and performance indicators for the evaluation of energy and moisture performance of buildings, including co-benefits whi

Social policies developed as means to ensure societal development in the context of rising capitalism and industrialization. Many countries transformed into modern welfare states addressing a wide range of social risks and social problems. Social policy entangled with economic growth both as a promoter of the ‘growth machine’ and as a mechanism to redistribute resources secured by economic develop

Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. Sialic acid plays a crucial role forpathogenic bacteria, since it is used as a source of car

Rationale: Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease pathogenesis. In clinical practice, trained readers will visually categorise positron emission tomography (PET) scans as either Aβ positive or negative. However, adjunct quantitative analysis is becoming more widely available, where regulatory approved software can currently generate metrics