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Intracranial hemorrhage as the initial manifestation of a congenital disorder of glycosylation

Intracranial hemorrhage in a term neonate is a rare event in the absence of an identifiable precipitating factor such as severe thrombocytopenia, mechanical trauma, asphyxia, infections, or congenital vascular malformations. Congenital disorders of glycosylation are a genetically and clinically heterogeneous group of multisystem disorders characterized by the abnormal glycosylation of a number of

El elogio irónico : la conciencia de lo erotikon como prueba de rectitud moral

Abstract in SpanishSe ha dicho a menudo que la Cronografía de Miguel Psellós, el prolífico autor del s. xi, es una obra historiográfica que semeja una novela y que Psellós gasta mucho tiempo en describir caracteres y en tomar actitudes irónicas respecto de sus protagonistas imperiales. Este artículo sostiene que una versión más refinada de esto puede ser vista en el libro sexto de Psellós a pro

A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?

The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may function through the regulation of cytokines, including interleukin-1 receptor antagonist (IL-1Ra), an inhibitor of phagocytosis. Using a mouse model relevant to ITP, we confirm an increase in mouse serum levels of IL-1Ra after exposure to IVIg,

The End Does Not Justify the Means : On How the Secondary EU Law Infringes the Primary EU Law in the Light of the Recent Judgments of the CJEU*

The constitutional character of the Union legal order based on the rule of law requires that secondary sources of Union law are not infringing the primary sources, including the Charter of the Fundamental Rights of the European Union (CFR). The latter’s importance as a valid instrument to be invoked against measures that are excessive in their interference with the fundamental rights has recently

Does production diversity support dietary diversity? : Evidence from pastoral and agro-pastoral households in West Pokot County, Kenya

Consumption of part of own-produced food is regarded as a sustainable approach to attaining dietary diversity and a pathway to improved food and nutrition security. However, empirical evidence on the relationship between production diversity and dietary diversity is inconclusive, with some studies demonstrating a positive relationship while others reveal conflicting results. Furthermore, this rela

Bio-Efficiency: On the valorisation of innovation in the bioeconomy

This article discusses a concept that institutions from the OECD to the EU increasingly employ in their response to the ecological crisis: The bioeconomy, wherein materials for economic activity would be bio-based and renewable. As a present-day project, the bioeconomy translates the critique of (fossil) carbon into patterns of (material) resource use and (economic) resource allocation, not least

Development of an All-Marine 3D Printed Bioactive Hydrogel Dressing for Treatment of Hard-to-Heal Wounds

Current standard wound care involves dressings that provide moisture and protection; however, dressings providing active healing are still scarce and expensive. We aimed to develop an ecologically sustainable 3D printed bioactive hydrogel-based topical wound dressing targeting healing of hard-to-heal wounds, such as chronic or burn wounds, which are low on exudate. To this end, we developed a form