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Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water : A pilot study in Ronneby, Sweden

Background: Perfluoroalkyl substances (PFAS) are widespread synthetic substances with various adverse health effects. A potential mechanism of toxicity for PFAS is via epigenetic changes, such as DNA methylation. However, few studies have evaluated associations between PFAS exposure and DNA methylation among adults, and data is especially scarce for women. Furthermore, exposure to environmental po

Contribution of Depolarization and Repolarization Changes to J-Wave Generation and Ventricular Fibrillation in Ischemia

Motility index measured by magnetic resonance enterography is associated with sex and mural thickness

Incidence differences between first primary cancers and second primary cancers following skin squamous cell carcinoma as etiological clues

Analytical validation of OncoMasTR, a multigene test for predicting risk of distant recurrence in hormone receptor-positive early stage breast cancer

Temporal responses of coastal hypoxia to nutrient loading and physical controls

A transthoracic Doppler echocardiography study of C-reactive protein and coronary microcirculation in children after open heart surgery.

Selective induction of inducible nitric oxide synthase in pancreatic islet of rat after an intravenous glucose or intralipid challenge.

Purification of recombinant and human apolipoprotein A-1 using surfactant micelles in aqueous two-phase systems: Recycling of thermoseparating polymer and surfactant with temperature-induced phase separation

Efficacy and safety of a new combination of calcipotriol and betamethasone dipropionate (once or twice daily) compared to calcipotriol (twice daily) in the treatment of psoriasis vulgaris: a randomized, double-blind, vehicle-controlled clinical trial.

Tau pathology distribution in Alzheimer's disease corresponds differentially to cognition-relevant functional brain networks

N-Terminal Prosomatostatin and Risk of Vascular Dementia

A Glucose/Oxygen Enzymatic Fuel Cell based on Gold Nanoparticles modified Graphene Screen-Printed Electrode. Proof-of-Concept in Human Saliva

Genetic anticipation in Swedish Lynch syndrome families

Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies wit

Association between betel nut consumption and folate deficiency among pregnant women in rural Bangladesh

International actors in environmental peacebuilding : a manifestation of neo-colonialism or practices of pragmatism?

In this paper, I explore the practice of environmental management by international actors in institutionally weak states transitioning from peace to conflict (post-conflict) to analyse how these actors may fill an institutional and legal gap. This is of interest as it moves the governance of the environment in the post-conflict states from a domestic to an international level. In post-conflict sta

Liver function in alpha-1-antitrypsin deficient individuals at 37 to 40 years of age

Severe alpha-1-antitrypsin (AAT) deficiency (PiZZ) is a risk factor for liver disease, but the prevalence of liver cirrhosis and hepatocellular cancer in PiZZ adults is unknown. The risk of liver disease in adults with moderate AAT deficiency (PiSZ) is also unknown. A cohort of 127 PiZZ, 2 PiZnull, 54 PiSZ, and 1 PiSnull individuals were identified by the Swedish national neonatal AAT screening pr

The gamma-tubulin meshwork as a therapeutic target

Cancer is a heterogeneous disease and treatment regime is dependent on type and location of the tumor. Several of the commonly used chemotherapeutics target the functions of the microtubules. One of the major problems with these drugs is the adverse effects associated with their use. Another problem many of the chemotherapeutics today face is resistance. Therefore there is a constant need for deve

A combination of clinical balance measures and FRAX® to improve identification of high-risk fallers

Background: The FRAX® algorithm quantifies a patient's 10-year probability of a hip or major osteoporotic fracture without taking an individual's balance into account. Balance measures assess the functional ability of an individual and the FRAX® algorithm is a model that integrates the individual patients clinical risk factors [not balance] and bone mineral density. Thus, clinical balance measures

Spontaneous vs nitroglycerin-induced vasovagal reflex on head-up tilt : Are there neuroendocrine differences?