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Add-on pramipexole for anhedonic depression : study protocol for a randomised controlled trial and open-label follow-up in Lund, Sweden

INTRODUCTION: Many depressed patients do not achieve remission with available treatments. Anhedonia is a common residual symptom associated with treatment resistance as well as low function and quality of life. There are currently no specific and effective treatments for anhedonia. Some trials have shown that dopamine agonist pramipexole is efficacious for treating depression, but more data is nee

Ethical Teachings of Abū Ḥāmid al-Ghazālī : Economics of Happiness

This book studies the interplay of economic philosophy and moral conduct as reflected in the writings of one of the most renowned scholars in Islamic history, Abū Ḥāmid al-Ghazālī (d. 1111). Al-Ghazālī contributed to Islamic theology, philosophy, and Sufism but is also regarded as one of the forerunners of classical economic thought in Islamic tradition.Al-Ghazālī made seminal contributions to the

Rethinking Transport in the Øresund Region: Policies, Strategies and Behaviours

Øresund EcoMobility contributes to knowledge creation for sustainable transport and green logistics, city transport, and energy systems with a specific focus on the conditions and needs of the Øresund region. In this book, long distance goods transport and strategies for green corridors through the Øresund and Europe are studied, multi-criteria models for analysis in transport and infrastructural

Implications of weighting factors on technology preference in net zero energy buildings

With the current movement towards Net Zero Energy Buildings (Net ZEBs) decisions regarding energy carrier weighting factors will have implications on which technologies could be favoured or disfavoured, and therefore adopted or not adopted, in the building sector of the near future. These implications should be taken into consideration by policy makers when developing legislation and regulations a

Uncertainties in Calibration of an Optical Spectrometer for Measuring Isotope Ratios in Methane : ACS Measurement Science Au

The stable isotope ratios of carbon (δ13C(CH4)) and hydrogen (δ2H(CH4)) in methane (CH4) from atmospheric air samples provide a tracer that can help distinguish the relative contribution of emission sources. These can be continuously measured at atmospheric monitoring stations by optical isotope ratio spectrometer (OIRS) instruments, providing data that is complementary to isotope ratio mass spect

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

The pathogenic mechanisms leading to neurodegeneration in Huntington disease (HD) are not fully understood but involve accumulation of toxic mRNA and protein products in the brain. Recent studies described an unconventional autophagic pathway involving DNA and RNA degradation through DNautophagy and RNautophagy that is regulated by the lysosomal protein SID1 transmembrane family member 2 (SIDT2).

Laparoscopy Diagnostic applications in suspected appendicitis and access-related complications

Laparoscopic surgery was introduced to minimize patient trauma. However, fatal technique specific complications, due to major vascular or visceral injury, were at times seen related to blind abdominal access using the Veress technique. A modified open access technique was developed and evaluated in 100 patients and found to be fast and easy to learn with few associated complications. This open te

Nucleic Acids as Drugs and Drug Targets With Focus on Anticancer Active Platinum Complexes and Small Interfering RNAs

Popular Abstract in Swedish Titeln på den här avhandlingen är ”Nukleinsyror som läkemedel och mål för läkemedel, med fokus på anticanceraktiva platinaföreningar och små interferande RNA”. Nukleinsyror är mer kända som sina förkortningar DNA och RNA. Anticanceraktiva platinaföreningar är en typ av läkemedel mot cancer. Små interfererande RNA är en slags reglermekanism för hur mycket av ett visst pr