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Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands.
BACKGROUND. Hypoxia induces increased tumor growth by promoting angiogenic and glycolytic pathways. Tumors expressing hypoxia-inducible factor-la (HIF-1 alpha), an important transcriptional activator of oxygen-regulated genes, are resistant to chemotherapy and radiotherapy. The major challenge in prostate cancer therapy today is to gain a better understanding of the development of hormone-refracto
Anthropometric Measures, Body Mass Index, and Pancreatic Cancer A Pooled Analysis From the Pancreatic Cancer Cohort Consortium (PanScan)
S100beta after coronary artery surgery: release pattern, source of contamination, and relation to neuropsychological outcome
Adsorption behaviour of amphiphilic polymers at hydrophobic surfaces: Effects on protein adsorption
Glacial survival or late glacial colonization? Phylogeography of the root vole (Microtus oeconomus) in north-west Norway
Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases
Histamine uptake by human endometrial cells expressing the organic cation transporter EMT and the vesicular monoamine transporter-2
Signaling via the Tgf-beta type I receptor Alk5 in heart development
Trophic factors secreted both from the endocardium and epicardium regulate appropriate growth of the myocardium during cardiac development. Epicardially-derived cells play also a key role in development of the coronary vasculature. This process involves transformation of epithelia] (epicardial) cells to mesenchymal cells (EMT). Similarly, a subset of endocardial cells undergoes EMT to form the mes
Quantitative adsorption and local structures of Gallium(III) at the water-alpha-FeOOH interface
Distance to hospital and utilization of surgical services in Haiti: do children, delivering mothers, and patients with emergent surgical conditions experience greater geographical barriers to surgical care?
Serum estradiol associates with blood hemoglobin in elderly men; The MrOS Sweden Study.
Complexity of a classical flow restoration problem
In this article, we revisit a classical optimization problem occurring in designing survivable multicommodity flow networks. The problem, referred to as FR, assumes flow restoration that takes advantage of the so-called stub release. As no compact linear programming (LP) formulation of FR is known and at the same time all known noncompact LP formulations of FR exhibit NP-hard dual separation, the
Satisfaction with rehabilitation in relation to self-perceived quality of life and function among patients with stroke - a 12 month follow-up.
Genetic Variants of GSK3B are Associated with Biomarkers for Alzheimer's Disease and Cognitive Function.
Background: Glycogen synthase kinase 3 beta (GSK3B) is the major kinase phosphorylating tau protein. Hyperphosphorylated tau is one of the hallmarks of Alzheimer's disease (AD). Despite extensive research, the role of GSK3B in AD pathogenesis is not fully understood. Objective: To evaluate possible associations between gene variants of GSK3B and risk of AD. Methods: Twelve GSK3B tag single-nucleot
Copeptin, a Marker of Vasopressin, Predicts Vascular Dementia but not Alzheimer's Disease
Spontaneous cross-species imitation in interaction between chimpanzees and zoo visitors
Imitation is a cornerstone in human development, serving both a cognitive function (e.g. in the acquisition and transmission of skills and knowledge) and a social-communicative function, whereby the imitation of familiar actions serves to maintain social interaction and promote prosociality. In nonhuman primates, this latter function is poorly understood, or even claimed to be absent, yet the evid
