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Genetic Traits Beneficial for Xylose Utilization by Recombinant Saccharomyces cerevisiae

Saccharomyces cerevisiae ferments hexoses in lignocellulosic hydrolysates under anaerobic conditions with high rates and ethanol yields. However, S. cerevisiae is naturally unable to utilize the pentose fraction of the hydrolysates. Xylose is the most abundant pentose sugar, and although recombinant S. cerevisiae strains capable of ethanolic xylose fermentation have been obtained through metabolic

Protein-Polymer Interaction and Association in Aqueous Solution

Popular Abstract in Swedish Syftet med den här avhandlingen har varit att studera association och växelverkan mellan proteiner och polymerer. Två olika tekniker har använts i dessa studier; datorsimuleringar och fördelning i polymera vattenhaltiga tvåfassystem. Vikten av att studera protein-polymer-växelverkan ligger i att flera biotekniska, och medicinska tillämpningar baserar sig just på protei

Spring flood induced shifts in Fe speciation and fate at increased salinity

Rivers have traditionally been viewed as negligible sources of iron (Fe) to marine waters, as most Fe gets lost during estuarine mixing. However, recent findings demonstrate that Fe from boreal rivers display a higher resistance towards salinity-induced aggregation, presumably due to stabilizing interactions with organic matter. Previous studies have shown that Fe (oxy)hydroxides are selectively r

What is the effect of giving the grazers access to additional nutrient sources on biodiversity in semi-natural pastures? A systematic review protocol

Background: Semi-natural pastures are unfertilized grasslands with a long history of traditional low-input grazing management. This kind of pastures are recognized for their high species richness. However, as a consequence of modernization of agriculture, many of the semi-natural pastures have been lost during the last century, leading to a serious threat to farmland biodiversity. Semi-natural pas

Assessing ecosystem services and multifunctionality for vineyard systems

Vineyards shape important economic, cultural, and ecological systems in many temperate biomes. Like other agricultural systems, they can be multifunctional landscapes that not only produce grapes, but also for example serve as wildlife habitat, sequester carbon, and are places of rich traditions. However, research and management practices often focus mostly on individual, specific ecosystem servic

Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Background: Delayed reconstruction of transection or laceration injuries of peripheral nerves is inflicted by a reduced regeneration capacity. Diabetic conditions, more frequently encountered in clinical practice, are known to further impair regeneration in peripheral nerves. Chitosan nerve guides (CNGs) have recently been introduced as a new generation of medical devices for immediate peripheral

European forest cover during the past 12,000 years : A palynological reconstruction based on modern analogs and remote sensing

Characterization of land cover change in the past is fundamental to understand the evolution and present state of the Earth system, the amount of carbon and nutrient stocks in terrestrial ecosystems, and the role played by land-atmosphere interactions in influencing climate. The estimation of land cover changes using palynology is a mature field, as thousands of sites in Europe have been investiga

Issues on transparency, accountability and control in hybrid organisations : The case of enterprises owned by local government

Our purpose is to critically discuss the quality of governability and scrutiny of, as well as insight in, enterprises owned by local government. Our analysis is empirically grounded in an in-depth case study of one of Sweden’s 10 largest municipalities. The ambition is to highlight troublesome areas and danger zones when it comes to public owning of corporations. We have consulted diverse types of

Worse breast cancer prognosis in insulin treated diabetic patients - A population based registry study in Sweden

Background. Diabetes may be linked to incidence of different tumor diseases and prognosis through various mechanisms such as the disease itself, hyperglycemia, obesity and anti-diabetes therapy. Material and methods. The study includes all women with BC diagnosed in Sweden between 2000 through 2008 (n=54406). The women had no previous cancer diagnosis during the period of 1958-1999. Dates of birth

Investigating the source of free fetal hemoglobin in preeclampsia. The role of the placenta and the fetus.

Preeclampsia (PE) is an important pregnancy complication that affects 3-8% of women worldwide and is a leading cause of maternal and fetal morbidity and mortality. It is known that PE is associated with placental dysfunction, resulting in hypoxia, oxidative stress, altered metabolism and production of inflammatory cytokines. Hypoxia could enhance erythropoiesis and induce non-erythroid hemoglobin