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In clinical practice, the glomerular filtration rate (GFR), a measurement of kidney functioning, is normally calculated using equations, such as the European Kidney Function Consortium (EKFC) equation. Despite being the most general equation, EKFC, just like previously proposed approaches, can still struggle to achieve satisfactory performance, limiting its clinical applicability. As a possible so

The nature of the surfaces of particles of pharmaceutical ingredients, food powders, and polymers is a determining factor for their performance in for example tableting, powder handling, or mixing. Changes on the surface structure of the material will impact the flow properties, dissolution rate, and tabletability of the powder blend. For crystalline materials, surface amorphization is a phenomeno

The dynamics of terrestrial ecosystems are shaped by the coupled cycles of carbon, nitrogen, and phosphorus, and these cycles are strongly dependent on the availability of water and energy. These interactions shape future terrestrial biosphere responses to global change. Here, we present a new terrestrial ecosystem model, QUINCY (QUantifying Interactions between terrestrial Nutrient CYcles and the

Photosystem II utilizes solar energy to drive electrons from the Mn cluster at the lumenal side to the quinone at the stromal side of the thylakoid membrane. The source of electrons is H2O, which is split to oxygen by the OEC. The water-splitting process involves cycling of the Mn-cluster through four semi-stable oxidation states, termed the S0, S1, S2, and S3 states. The OEC can be trapped in the

Background and Purpose - Warfarin prevents stroke in atrial fibrillation (AF); however, concerns regarding international normalized ratio control and hemorrhage limit its use in the elderly. The oral direct thrombin inhibitors (DTIs) are potential alternatives to warfarin, offering fixed dosing without drug and dietary interactions and the need for international normalized ratio monitoring. Althou

By exposing photosystem II (PSII) samples to an incrementing number of excitation flashes at room temperature, followed by freezing, we could compare the Mn-derived multiline EPR signal from the S-2 oxidation state as prepared by 1, 5, 10, and 25 flashes of light. While the S-2 multiline signals exhibited by these samples differed very little in spectral shape, a significant increase of the relaxa

Fouling is one the most important challenges to apply membrane technology on industrial scale in the food industry. Despite significant progress in understanding and preventing fouling and in developing appropriate membrane cleaning protocols, both fouling and cleaning remain key challenges in membrane plant operation in the food industry with a significant impact on membrane plants capital (CAPEX