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Evaluation of the Forsvall biopsy needle in an ex vivo model of transrectal prostate biopsy–a novel needle design with the objective to reduce the risk of post-biopsy infection

Background: Transrectal prostate biopsy (TRbx) transfers colonic bacteria into prostatic tissue, potentially causing infectious complications, including sepsis. Our objective was to determine whether biopsy needle shape, surface properties and sampling mechanism affect the number of bacteria transferred through the colon wall, and evaluate a novel needle with improved properties. Methods: The stan

Diving response and apneic time in humans

The aim of this study was to compare apneic time with the human diving response, defined as heart rate (HR) reduction and reduced skin blood flow, in groups with varying degrees of breath-hold diving experience. Apneic time and HR reduction at apneas in air and apneas with face immersion in cold water were thus recorded in nine groups. Skin capillary blood flow was recorded in six of the groups. A

Parkinsonism in Genetic Neurodevelopmental Disorders : A Systematic Review

Background: With advances in clinical genetic testing, associations between genetic neurodevelopmental disorders and parkinsonism are increasingly recognized. In this review, we aimed to provide a comprehensive overview of reports on parkinsonism in genetic neurodevelopmental disorders and summarize findings related to genetic diagnosis, clinical features and proposed disease mechanisms. Methods:

Prediction of lake water-level fluctuations using adaptive neuro-fuzzy inference system hybridized with metaheuristic optimization algorithms

Lakes help increase the sustainability of the natural environment and decrease food chain risk, agriculture, ecosystem services, and leisure recreational activities locally and globally. Reliable simulation of monthly lake water levels is still an ongoing demand for multiple environmental and hydro-informatics engineering applications. The current research aims to utilize newly developed hybrid da