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The use of restricted access media and other stationary phases for clean-up and trace enrichment of environmental samples coupled on-line to liquid chromatography using diode array detection as well as thermospray MS is described. This on-line configuration was compared with commercially available ELISAs for the determination of triazines in complex matrices, showing superior precision and accurac

Cerebellar control of movements is dependent on mossy fiber input conveying information about sensory and premotor activity in the spinal cord. While much is known about spino-cerebellar systems, which provide the cerebellum with detailed sensory information, much less is known about systems conveying motor information. Individual motoneurones do not have projections to spino-cerebellar neurons. I

Anti-phospholipid (aPL) antibodies are important contributors to development of thrombosis in patients with the autoimmune rheumatic disease systemic lupus erythematosus (SLE). The underlying mechanism of aPL antibody-mediated thrombosis is not fully understood but existing data suggest that platelets and the complement system are key components. Complement activation on platelets is seen in SLE p

The healthcare sector is one of the fastest growing economic sectors of today. The medical device domain is one part of that sector. An increasing part of functionality in medical devices and systems is implemented in software and many features should not be possible to implement without software. The use of medical software is an inherent risk to the patient and the outcome of a failure can vary

1. Geolocation by light allows for tracking animal movements, based on measurements of light intensity over time by a data-logging device (geolocator). Recent developments of ultra-light devices (<2 g) broadened the range of target species and boosted the number of studies using geolocators. However, an inherent problem of geolocators is that any factor or process that changes the natural light in

Popular Abstract in Swedish Arkitekten Hans Westman var verksam i Skåne från 1932 till 1983. Hans rika och mångskiftande produktion har satt sin prägel på den moderna skånska arkitekturen, särskilt i Lund där han hade sitt arkitektkontor. Westmans arkitektur spänner över ett brett fält från bostadshus, offentliga byggnader, kraftverk till kyrkor och kloster. Flera verk är välkända, t ex radhusområ

Popular Abstract in Swedish Diskussionen tar sin utgångspunkt i den klyfta som finns mellan, å ena sidan, stora delar av forsknings- och policy-världen och, å andra sidan, den verklighet som författaren stött på ute på den afrikanska landsbygden. Forskningsvärlden ser vattenresurser som en rent ekonomisk tillgång och småskaliga bönder beskrivs såsom vinstmaximerande individer, medan verkligheten äAllocation, control, and management of natural resources are issues that absorb researchers within both the social and natural sciences. This study deals with such research questions as well as with one of the most fundamental issues in Economic History – namely institutional change. The plot is set around continuity and change of property rights institutions governing water resources. The setting

The increasing emissions of carbon dioxide from fossil fuel burning are today thought to be one of the main contributors to global warming. At the same time, developing countries are striving for an increased welfare and burning more fossil fuel, which in turn is augmenting the greenhouse gas effect. In this thesis the current understanding of the connection between greenhouse gases and the climat

The objective of this study is to contribute to the discussion about linking society and nature in environmental research. It is an attempt to provide a critical analysis of the "Industrial Metabolism" studies, which have been based on a flow perspective and have argued that such a perspective is essential to the search for environmentally sustainable societal development paths and could serve as

Popular Abstract in Swedish De fyra studier som ingår i denna avhandling är gjorda för att undersöka eventuella oönskade effekter av läkemedel på näthinnan. Näthinnan är en del av det centrala nervsystemet och känslig för toxiska substanser. För att skydda näthinnan så finns två barriärer – en yttre och en inre blod–näthinne- barriär. Dessa barriärer består av strukturer som håller samman celler iThe adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. Rifabutin is a broad spectrum antibiotic with known ocular adverse effects (corneal opacities, uveitis and vascular ret

Popular Abstract in Swedish Utveckling av en flerdimensionell residual-distributions lösare för Large Eddy Simulation av industriell turbulenta strömningar.This thesis presents the results of the author's research activity to develop a time-space accurate flow-solver for Large Eddy Simulations (LES), based on the Multidimensional Residual Distribution approach. The aim of this work is the attempt to develop a compact high-order algorithm which includes multidimensional flow physics, in hope of creating a better algorithm for LES of turbulent compress

Popular Abstract in Swedish Vi har studerat hur man kan använda immunsystemet för att behandla råttor med hjärntumör (maligna gliom). Eftersom råttor väldigt sällan utvecklar hjärntumörer, så måste vi injicera tumörceller i hjärnan själva. Om djuren inte får någon behandling dör de vanligen inom ca. 24 dagar. Får de däremot en injektion i buken eller under huden på benet med genmanipulerade tumörcMalignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. Because of the poor prognosis, several additional therapies have been investigated and are under development, such a