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Zinc is an essential micronutrient for all living organisms. It is required for signalling and proper functioning of a range of proteins involved in, for example, DNA binding and enzymatic catalysis. In prokaryotes and photosynthetic eukaryotes, Zn(2+)-transporting P-type ATPases of class IB (ZntA) are crucial for cellular redistribution and detoxification of Zn(2+) and related elements. Here we p
OBJECTIVE: Hyperglycemia is a recognized risk factor for cardiovascular disease in diabetes. Recently, we reported that high glucose activates the Ca(2+)/calcineurin-dependent transcription factor nuclear factor of activated T cells (NFAT) in arteries ex vivo. Here, we sought to determine whether hyperglycemia activates NFAT in vivo and whether this leads to vascular complications. METHODS AND RES
Ett nytt sätt att diagnostisera graviditetsdiabetes Allt fler gravida i Sverige får diagnosen graviditetsdiabetes. Forskarna vet fortfarande inte orsaken till varför man får graviditetsdiabetes. Allt mer forskning pekar på att kronisk inflammation kan ligga bakom sjukdomens uppkomst och att inflammatoriska markörer skulle kunna användas för att säkrare och tidigare ställa diagnosen. Graviditets
Sammanfattning Examenarbetets titel: Personal branding – möjlighet eller krav? Seminariedatum: 2015-01-15 Ämne/kurs: FEKH29 Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Magnus Skog, Justus Jahja, Niran Ahmad Handledare: Jon Bertilsson Nyckelord: Sociala medier, varumärke, företagsledare, finansiellt resultat Syfte: Uppsatsens syfte är att i eAbstract Title: Personal branding – opportunity or necessity? Seminar date: 2015-01-15 Course: FEKH29 Business administration: Degree Project in Marketing, Undergraduate Level, 15 hp. Authors: Magnus Skog, Justus Jahja, Niran Ahmad Advisor: Jon Bertilsson Key words: Social media, brands, Ceo, financial result Objective: The objective of this thesis is to in an explorative approach obtain th
The elderly population within the European Union is growing where as the amount of caregivers is not. The objective of the NavMem project is to make older citizens more self-sufficient and confident specifically while traveling on foot. This could potentially lead to a more active and social life while decreasing the need of senior citizen care. With this objective in mind the NavMem consortium ha
This thesis explores the name, naming and naming politics in three poetic texts which exhibit a concern with the normative force of language: Cristina Peri Rossi’s Evohé (1971), Julia Álvarez’ The Other Side/El otro lado (1995) and Ana Arzoumanian’s (2006) Juana I. In Evohé the woman-body and the woman-word collide and penetrate each other; in The Other Side/ El otro lado the English code conflict
Det finns ingen tydlighet i vad instrumentkännedom i piano innefattar. Vi ser att pianots konstruktion, egenskaper och instrumentkännedom skiljer sig märkbart på akustiska och digitala pianoinstrument. Studiens bakgrund är kopplad till våra egna erfarenheter som pianolärarstudenter och framtida pianolärare. Vårt syfte med studien är att ta reda på vad instrumentkännedom innebär för olika pianoläraThere is no clarity on what instrument knowledge in piano should contain. We can see that the construction, functions and instrument knowledge vary significantly depending on if it is an acoustic or digital piano instruments. The background of the study is based on our own backgrounds and experiences as students and future piano teachers. Our purpose with the study is to learn what instrument know
Eftersom innovation ger konkurrensfördelar, ökar marknadsandelar och påskyndar den övergripande institutionella tillväxten, utgör innovation en erkänd framgångsfaktor för organisationer. Under det senaste decenniet har ett paradigmskifte från traditionella innovationsstudier, med fokus på forskning och utveckling, till medarbetardriven innovation (EDI) skett. Då den senaste litteraturkartläggninge
Coordination of fetal maturation with birth timing is essential for mammalian reproduction. In humans, preterm birth is a disorder of profound global health significance. The signals initiating parturition in humans have remained elusive, due to divergence in physiological mechanisms between humans and model organisms typically studied. Because of relatively large human head size and narrow birth
We compared hippocampal volume measures obtained by manual tracing to automatic segmentation with FreeSurfer in 44 younger (20–30 years) and 47 older (60–70 years) adults, each measured with magnetic resonance imaging (MRI) over three successive time points, separated by four months. Retest correlations over time were very high for both manual and FreeSurfer segmentations. With FreeSurfer, correla
A major barrier for cancer immunotherapy is the presence of suppressive cell populations in patients with cancer, such as myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM), which contribute to the immunosuppressive microenvironment that promotes tumor growth and metastasis. Tasquinimod is a novel antitumor agent that is currently at an advanced stage of clinical develo
