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The economic impact of moderate stage Alzheimer's disease in Italy : Evidence from the UP-TECH randomized trial

Background: There is consensus that dementia is the most burdensome disease for modern societies. Few cost-of-illness studies examined the complexity of Alzheimer's disease (AD) burden, considering at the same time health and social care, cash allowances, informal care, and out-of-pocket expenditure by families. Methods: This is a comprehensive cost-of-illness study based on the baseline data from

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The vision is certainly the most developed sense in raptors, and these birds are cosidered as the vertebrates with the greatest visual acuity. However, raptors are among the most frequent victims of collisions with wind turbines and other human features. Given the conservation issues and the cost of conservation operations , it is essential to understand how sensory abilities of raptor affect thei

A Collective Picture of What Makes People Happy: Words Representing Social Relationships, not Money, are Recurrent with the Word ‘Happiness’

Using green infrastructure for urban climate-proofing : An evaluation of heat mitigation measures at the micro-scale

Reactivity of dissolved organic matter in response to acid deposition

The role of complement inhibitors beyond controlling inflammation

Modifying Backoff Freezing Mechanism to Optimize Dense IEEE 802.11 Networks

The evolution of innate immune genes : Purifying and balancing selection on β-Defensins in waterfowl

In disease dynamics, high immune gene diversity can confer a selective advantage to hosts in the face of a rapidly evolving and diverse pathogen fauna. This is supported empirically for genes involved in pathogen recognition and signalling. In contrast, effector genes involved in pathogen clearance may be more constrained. b-Defensins are innate immune effector genes; their main mode of action is

Clarification of the risk for venous thrombosis associated with hereditary protein S deficiency by investigation of a large kindred with a characterized gene defect

Vulnerability as a Key Concept in Museum Pedagogy on Difficult Matters

Pituitary adenylate cyclase-activating polypeptide and islet amyloid polypeptide in primary sensory neurons : Functional implications from plasticity in expression on nerve injury and inflammation

Primary sensory neurons serve a dual role as afferent neurons, conveying sensory information from the periphery to the central nervous system, and as efferent effectors mediating, e.g., neurogenic inflammation. Neuropeptides are crucial for both these mechanisms in primary sensory neurons. In afferent functions, they act as messengers and modulators in addition to a principal transmitter; by relea

Characterization of carotenoids in Rhodothermus marinus

Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production

Alteration of PACAP distribution and PACAP receptor binding in the rat sensory nervous system following sciatic nerve transection

In Situ Synchrotron X-ray Diffraction Analysis of the Setting Process of Brushite Cement : Reaction and Crystal Growth

Brushite cements are fast self-setting materials that can be used as bone substitute materials. Although tracing their fast setting process is a challenge, it is important for the understanding of the same, which in turn is important for the material's further development and use in the clinics. In this study, the setting rate, phase formation, and crystal growth of brushite cements were quantitat

The interaction between predation risk and food ration on behavior and morphology of Eurasian perch

Effects of monobutyrin and tributyrin on liver lipid profile, caecal microbiota composition and SCFA in high-fat diet-fed rats

Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients

Comparison of dual mobility cup and other surgical construts used for three hundred and sixty two first time hip revisions due to recurrent dislocations : five year results from Lithuanian arthroplasty register

Including a one-year grass ley increases soil organic carbon and decreases greenhouse gas emissions from cereal-dominated rotations – A Swedish farm case study