Filetype
Cerebrospinal fluid (CSF) levels of amyloid-β 42 (Aβ42) and tau have been evaluated as endophenotypes in Alzheimer’s disease (AD) genetic studies. Although there are sex differences in AD risk, sex differences have not been evaluated in genetic studies of AD endophenotypes. We performed sex-stratified and sex interaction genetic analyses of CSF biomarkers to identify sex-specific associations. Dat
Purpose: Stringent variant interpretation guidelines can lead to high rates of variants of uncertain significance (VUS) for genetically heterogeneous disease like long QT syndrome (LQTS) and Brugada syndrome (BrS). Quantitative and disease-specific customization of American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) guidelines can address this false neg
Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired controls from two multicenter cohorts: King's College London (n = 805) and the Swedish BioFINDER study (n =
We present an overview of the 4MOST project at the Preliminary Design Review. 4MOST is a major new wide-field, high-multiplex spectroscopic survey facility under development for the VISTA telescope of ESO. 4MOST has a broad range of science goals ranging from Galactic Archaeology and stellar physics to the high-energy physics, galaxy evolution, and cosmology. Starting in 2021, 4MOST will deploy 24
Objective: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all ischemic stroke and is a major manifestation of cerebral small vessel disease, the primary cause of vascular cognitive impairment. Studies across neuro
Dementia is a global problem and major target for health care providers. Although up to 45% of cases are primarily or partly due to cerebrovascular disease, little is known of these mechanisms or treatments because most dementia research still focuses on pure Alzheimer's disease. An improved understanding of the vascular contributions to neurodegeneration and dementia, particularly by small vessel
OBJECTIVES: The objective of this study is to clarify the role of (G4C2)n expansions in the etiology of Parkinson disease (PD) in the worldwide multicenter Genetic Epidemiology of Parkinson's Disease (GEO-PD) cohort. METHODS: C9orf72 (G4C2)n repeats were assessed in a GEO-PD cohort of 7,494 patients diagnosed with PD and 5,886 neurologically healthy control individuals ascertained in Europe, Asia,
Context. Open clusters are key tools to study the spatial distribution of abundances in the disk and their evolution with time. Aims. Using the first release of stellar parameters and abundances of the Gaia-ESO Survey, we analyse the chemical properties of stars in three old/intermediate-age open clusters, namely NGC 6705, NGC 4815, and Trumpler 20, which are all located in the inner part of the G
A rare loss-of-function allele p.Arg138* in SLC30A8 encoding the zinc transporter 8 (ZnT8), which is enriched in Western Finland, protects against type 2 diabetes (T2D). We recruited relatives of the identified carriers and showed that protection was associated with better insulin secretion due to enhanced glucose responsiveness and proinsulin conversion, particularly when compared with individual
BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte
8-12 June 2026 School of Architecture at Lund University invites you to the presentation days for the degree projects of the A-programme (AAHM01) from 8-12 June 2026. The presentations are public and take place in the Full Scale Lab, A-building, Klas Anshelms väg 16, 223 62 Lund. Max Carlsson / Mer än en arena: Norra Hovstallängen UppsalaThis thesis develops a proposal for a new arena at Norra Ho
https://www.architecture.lth.se/education/degree-projects/programme-in-architecture - 2026-05-29
Produkt- och tjänstekatalog MEDIA-TRYCK | LU SERVICE | LUNDS UNIVERSITET PRODUKTKATALOG Med reservation för prisändringar och eventuella tryckfel Copyright Media-Tryck Typsnitt Adobe Garamond Pro och Frutiger Papper i inlagan Scandia smooth white 130 gr Omslagspapper Tryck Scandia smooth white 300 gr Media-Tryck, Lund Efterbehandling Media-Tryck Webb www.mediatryck.lu.se Layout Jonas Palm Media-Tr
https://www.mediatryck.lu.se/en/sites/mediatryck.lu.se.en/files/produktkatalog.pdf - 2026-05-29
Produkt- och tjänstekatalog 2017 MEDIA-TRYCK | LU SERVICE | LUNDS UNIVERSITET PRODUKTKATALOG 2017 Med reservation för prisändringar och eventuella tryckfel Copyright Media-Tryck Typsnitt Adobe Garamond Pro och Frutiger Papper i inlagan Scandia smooth white 130 gr Omslagspapper Scandia smooth white 300 gr Tryck Media-Tryck, Lund 2017 Efterbehandling Media-Tryck Webb www.mediatryck.lu.se Layout Jona
https://www.mediatryck.lu.se/en/sites/mediatryck.lu.se.en/files/produktkatalog_2017.pdf - 2026-05-29
TITLE Master’s Dissertation Structural Mechanics EMIL HOLST SNECKENBORG PARAMETRIC DESIGN OF WIND TURBINE FOUNDATIONS Enhancing Efficiency Through Automated Modeling DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--24/5276--SE (1-85) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisors: Professor KENT PERSSON, Division of Structural Mechanics, LTH and BABAK NAVI
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5276.pdf - 2026-05-28
Licentiate Dissertation Structural Mechanics VEDAD ALIC Report TV SM -3075 V ED A D A LIC N U M ER IC A L M ETH O D S FO R C O N C EPTU A L STR U C TU R A L D ESIG N NUMERICAL METHODS FOR CONCEPTUAL STRUCTURAL DESIGN DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--16/3075--SE (1-107) | ISSN 0281-6679 ISBN 978-91-7623-733-5 (print) | 978-91-7623-734-2 (Pdf) LI
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm3000/web3075.pdf - 2026-05-28
fncel-14-00146.pdf REVIEW published: 29 May 2020 doi: 10.3389/fncel.2020.00146 Edited by: Sofia Grade, Institute of Molecular Biotechnology (OeAW), Austria Reviewed by: Daniel Tornero, University of Barcelona, Spain Afsaneh Gaillard, University of Poitiers, France *Correspondence: Anders Björklund anders.bjorklund@med.lu.se Specialty section: This article was submitted to Cellular Neuropathology,
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_frontiers.pdf - 2026-05-29
Fredrik.doc Binding Condition C and Derivation by Phase 1 FREDRIK HEINAT 1 Introduction In earlier theories of generative grammar (e.g. Chomsky 1981), the checking of binding conditions has generally been assumed to take place at Surface-structure or at Logical Form, LF, after reconstruction (see Belletti and Rizzi 1988, among others for applying binding theory at Deep-structure). Up till Chomsky
https://www.sol.lu.se/fileadmin/media/forskning/workingpapers/engelska/vol02/Fredrik.pdf - 2026-05-28
The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for BRCA2 mutation carriers, we undertook a two-staged genome-wide association study in BRCA2 mutation carriers. In stage 1 using the Affymetrix 6.0 platform, 592,163 filtered SNPs genotyped were available on 89
