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Neisseria meningitidis is a causative agent of meningitis. Despite vaccination programs, it still causes a large number of deaths in young children. Early diagnosis followed by passive immunization with human monoclonal antibodies could be an approach to effective therapy. Peripheral blood lymphocytes from normal, healthy blood donors and from vaccinated individuals were immunized in vitro, using
The emerging debate on transnational populism has thus far mainly focused on cases, which have remained relatively inconsequential due to the weak institutionalisation of the political transnationalism arena. By bringing in a better-structured arena of migrant transnationalism, this paper introduces populist political parties mobilising transnational migrants to the debate and explores the resulti
Agenda 2030 Graduate School monthly newsletter #5 2025-05-13 Ylva van Meeningen Hi! First of all, a big shout out to Billy and Linn for successfully defending your thesis! Congratulations and we could not be more proud of you within the graduate school! This past week, Lund University has together with the municipality of Lund organized the Sustainability week. It is an annual event which organize
Science Journals — AAAS Xhonneux et al., Sci. Transl. Med. 13, eabd5666 (2021) 31 March 2021 S C I E N C E T R A N S L A T I O N A L M E D I C I N E | R E S E A R C H R E S O U R C E 1 of 15 M E T A B O L I S M Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression Louis-Pascal Xhonneux1,2, Oliver Knight1,2, Åke Lernmark3, Ezio Bonifacio4, William A. Hag
https://www.teddy.lu.se/sites/teddy.lu.se/files/2022-01/130%2009242021_679_130_MP233_Xhonneux_SciTranslMed_2021.pdf - 2026-07-17
DC230036_proof.pdf Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5–15-Year-Old Children Followed in the TEDDY Study Xiang Liu, Suzanne Bennett Johnson, Kristian F. Lynch, Kerry Cordan, Russell Pate, Martha D. Butterworth, Åke Lernmark, William A. Hagopian, Marian J. Rewers, Richard A. McIndoe, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer
https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/150_2.pdf - 2026-07-17
Huruvida en skiljeklausul i det ursprungliga kontraktet blir giltig mellan successor och kvarvarande part vid singularsuccession finns inte reglerat i svensk lag och har varit föremål för delade meningar. Den ledande uppfattningen i doktrin var länge att skiljeklausulen kunde göras gällande mot successor om han ägt eller bort äga kännedom om klausulen. Se exempelvis Dillén och Hassler. Heuman fram
Yellow rust (Puccinia striiformis f. sp. Tritici) is a crop disease caused by a fungus that regularly infects wheat and causes yield loss in Ethiopia. The disease has a significant impact on the country’s crop production, food security, health, and socioeconomic well-being. Anticipating yellow rust epidemics can help to better manage them and mitigate their adverse impacts. This study explores t
This work investigates the prospective impacts of climate change on wind-driven rain (WDR) and walls through simulating the hygrothermal performance of rain screen of common vertical wall constructions for the climatic conditions of Gothenburg in Sweden. While a substantial amount of work has been done on the impact of climate change on the thermal performance of buildings, this paper studies its
Invasive exotic plant species are often expected to benefit exclusively from legacy effects of their litter inputs on soil processes and nutrient availability. However, there are relatively few experimental tests determining how litter of exotic plants affects their own growth conditions compared to congeneric native plant species. Here, we test how the legacy of litter from three exotic plant spe
Effects of the addition of a cationic amino acid-based synthetic amphiphile, arginine N-lauroyl amide dihydrochloride (ALA), to a lipid-based transfection formulation have been investigated. It is shown that the inclusion of ALA results in a substantial enhancement of the transfection capability of lipoplexes prepared with liposomes of 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine and chol
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the development of novel, rational treatment options targeting terminal complement activation, e.g., using an anti-C5 antibody (eculizumab). We review treatment and patient management issues related to this therapeutic approach. We present consensus cl
Context: Inflammation and adipogenesis are two parallel processes with increased activity in severe Graves' ophthalmopathy. Objective: The aim of this work was to define target genes for therapeutic intervention in adipogenesis and inflammation in Graves' ophthalmopathy. Design: Orbital tissue was obtained from patients with ophthalmopathy in acute or chronic phase undergoing orbital surgery to st
The aim of this study was to determine the threshold of fracture probability at which interventions become cost-effective. We modeled the effects of a treatment costing $500/year, given for 5 years, that decreased the risk of all osteoporotic fractures by 35%, followed by a waning of effect for 5 years. Sensitivity analyses included a range of effectiveness (10%-50%) and a range of intervention co
Following the outbreak of new media technologies, researchers in museum studies have acknowledged the increasing importance of digital content creation for museums. Today, Social Media provides museums with the opportunity to engage with their audiences beyond museum walls and pursue their organizational mission in innovative ways. Despite a growing interest in the organizational changes that make
Augmented reality (AR) is increasingly being adopted in fashion retail to enhance customer ex-perience, boost engagement, and reduce uncertainty in online shopping environments. While AR offers both hedonic and utilitarian value, its implementation across large multinational fashion companies remains inconsistent due to financial, technological, and organizational barriers. This study investigates
As Climate Change increases the frequency and severity of wildfires in British Columbia, communities at the Wildland Urban Interface face escalating risks. This thesis explores the challenges and opportunities of community engagement in wildfire management in the city of Kamloops, one of the most fire-prone urban areas in British Columbia. Employing a single-case study design, the research is base
In recent years, Predictive Digital Twins (PDT) have emerged as a potential tool to monitor and predict the behavior of dynamic systems, including nature-based solutions in natural coastal systems. Here, we test the potential of using a simple, coupled shoreline and beach-dune model as a base for a PDT. The models exchange sediment flux balance information at each time step and recalculate shoreli
