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The evaluation of modelling diagnostics with appropriate observations is an important task that establishes the capabilities and reliability of models. In this study we compare aerosol and cloud properties obtained from three different climate models (ECHAM-HAM, ECHAM-HAMSALSA, and NorESM) with satellite observations using Moderate Resolution Imaging Spectroradiometer (MODIS) data. The simulator M
The Sagittarius dwarf spheroidal galaxy is in an advanced stage of disruption but still hosts its nuclear star cluster (NSC), M54, at its center. In this paper, we present a detailed kinematic characterization of the three stellar populations present in M54: Young metal-rich (YMR); intermediate-age metal-rich (IMR); and old metal-poor (OMP), based on the spectra of 6500 individual M54 member stars
We present a young male patient with breast cancer having several risk factors likely acting in consort: irradiation of the breast for gynecomastia in adolescence and a life-long administration of phenothiazine for schizophrenia from the age of 16 years, with elevated serum prolactin level resulting in breast cancer development 24 years after irradiation.
Resonant excitation to the F1s-σ* dissociative state in hydrogen fluoride gives a photoelectron spectrum where the spectator part contains strong atomic lines but a participator part where such lines are lacking. We demonstrate that this contrasting behaviour between the two parts is due to a strong dynamical suppression of the resonant contribution, making direct main state photoionization the do
The peaks arising from the decay of the excited oxygen atom were studied. Fast dissociation of core-excited ozone was confirmed by the presence of Auger emission from atomic oxygen in the decay spectrum from the ozone OT 1s-σ*(7a1) state. No such emission was observed after excitation of the corresponding state on the central oxygen atom. An angle-dependent energy shift of the atomic lines was obs
BACKGROUND.: To better define subpopulations in which achieving adequate mycophenolic acid (MPA) concentrations quickly would be important, a post hoc exploratory analysis on the fixed-dose concentration-controlled database was performed, comparing high- versus low-risk renal transplant patients. METHODS.: Renal transplant patients were treated with mycophenolate mofetil, corticosteroids, and cycl
The chemical origin of the firefly bioluminescence has been investigated by means of density functional and multireference theoretical methods. Different hypotheses on the mechanism of multicolour emission have been investigated: twisting around the central carbon–carbon bond, polarizability of the oxyluciferin microenvironment and presence of resonance structures. The calculated results indicated
Background: The involvement of aquaporin (AQP) water and small solute channels in the etiology of several diseases, including cancer, neuromyelitis optica and body fluid imbalance disorders, has been suggested previously. Furthermore, results obtained in a mouse model suggested that AQP9 function contributes to hyperglycemia in type-2 diabetes. In addition, the physiological role of several AQP fa
The combination of polyethylenimine (PEI), as a plasmid DNA pre-condensing agent, and cationic lipids has been reported to result in a synergistic effect on transfection. Recently, we have explored this effect by associating low-molecular weight PEIs with transferrin-associated lipoplexes using different cationic liposome formulations. The resulting lipopolyplexes that have shown to be the most ef
Lime–hemp concrete (LHC) is a sustainable building material that combines hemp shiv and building limes. Moisture fixation and thermal properties of LHC were determined so as to gain knowledge about the material’s behaviour in a cold, wet climate. Sorption isotherms were produced over the whole moisture range for two LHC mixes by means of glass jar tests and a pressure plate apparatus. Thermal prop
This article studies contemporary Australian copyright and contrasts this to a large-scale online survey on file sharing in order to analyse the seemingly parallel and non-compliant legal and social norms that they represent. Furthermore, a selection of 3,575 Australian respondents to an online survey is compared to a large scale near global group of over 96,000 respondents, allowing determining d
Background: Most studies assessing health effects of neighborhood characteristics either use self-reports or objective assessments of the environment, the latter often based on Geographical Information Systems (GIS). While objective measures require detailed landscape data, self-assessments may yield confounded results. In this study we demonstrate how self-assessments of green neighborhood enviro
Impoliteness has been considered as a marginal phenomenon for scientific research for some time, although as a type of behaviour it has always been around us. The field of impoliteness studies is currently growing, but there are clear gaps in the research that concerns the conventionality of expressions, different semiotic systems through which impoliteness is expressed and cross-cultural comparis
This thesis combines a number of methodologies and measures in order to address the processing of two types of negation (with not and un) in relation to each other and to non-negated affirmative meanings. The four investigations in this thesis target the processing of these meanings at different levels, namely the word level (Study 1) and sentence level (Studies 2–4). In two artificial language le
Introduction: Patients with severe haemophilia A (HA) with no family history of haemophilia will be diagnosed upon their first bleeding event. Methods: Herein, we studied the effects of lack of family history in HA and the subsequent delay of diagnosis on bleeding pattern and early treatment, as well as on the risk of inhibitor development. For this purpose, data on 1237 severe HA patients with kn
Aim: To determine the incidence of late intracranial vitamin K deficiency bleeding (VKDB) in The Netherlands using the Dutch Pediatric Intensive Care Evaluation (PICE) registry. Methods: The PICE registry was used to identify all infants who were admitted to a Dutch pediatric intensive care unit (PICU) with intracranial bleeding between 1 January 2004 and 31 December 2007. Cases of confirmed late
The disorders of serine biosynthesis are a group of inborn errors of metabolism characterised by congenital microcephaly, seizures and severe psychomotor retardation. Although these disorders are rare the prompt recognition of serine deficiency is important as these disorders are treatable. The diagnosis is based on decreased concentrations of serine in cerebrospinal fluid (CSF). It has previously
The difference from 4 to 6 σ in the Hubble constant (H0 ) between the values observed with the local (Cepheids and Supernovae Ia, SNe Ia) and the high-z probes (Cosmic Microwave Background obtained by the Planck data) still challenges the astrophysics and cosmology community. Previous analysis has shown that there is an evolution in the Hubble constant that scales as f (z) = H0/(1 + z)η, where H0
Samples for isolation of dictyostelid cellular slime molds were obtained from 20 collecting sites at 18 localities in south central and southeastern Madagascar during May 2009. At least thirty species of dictyostelids representing seven genera were recovered from 52 samples of soil/humus. This total included 17 species described as new to science, 13 species already known from various localities t
