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Vertebral fracture risk is a heritable complex trait. The aim of this study was to identify genetic susceptibility factors for osteoporotic vertebral fracture applying a genome-wide association study (GWAS) approach. The GWAS discovery was based on the Rotterdam Study, a population-based study of elderly Dutch individuals aged >55 years; and comprising 329 cases and 2666 controls with radiographic
The paper is a sounding of Ulrich Beck's and Edgar Grande's conceptual map of the varieties of second modernity - Western and Non-Western, European and beyond - that makes up today's world. Their mapping is examined in the light of two, striking analytical perspectives associated with Ulrich Beck: everyday 'cosmopolitization' and his call for a methodological cosmopolitanism. A line of inquiry exp
In 2019 the first neutrons will be fired at the ESS plant, at least to its present plan, located in the outskirts of Lund, the brightest neutron facility in the world. In the scientists’ self-images, this kind of high technology and international cooperative knowledge production is entitled Big Science or Global Science. The concept “technoscience” isn’t used. This chapter will discuss if the conc
The purpose of this study is to elucidate affordances and meaning-making processes where students in Compulsory lower secondary education learn to play music together in music class. The data consists of a series of observed music lessons, performances and stimulated recall interviews in two 8th form classes, video recorded in the course of one term. The analysis focuses on students’ and their tea
PURPOSE: To evaluate, preclinically, the potential for dose escalation of continuous, hyperfractionated, accelerated radiation therapy (CHART) for non small-cell lung cancer (NSCLC), we examined the strategy of omission of elective nodal irradiation with and without the application of three-dimensional conformal radiation technology (3DCRT). METHODS AND MATERIALS: 2D, conventional therapy plans we
Background. During early mouse development, two extra-embryonic lineages form alongside the future embryo: the trophectoderm (TE) and the primitive endoderm (PrE). Epigenetic changes known to take place during these early stages include changes in DNA methylation and modified histones, as well as dynamic changes in gene expression. Results. In order to understand the role and extent of chromatin-b
Transport energy conservation research in urban transport systems dates back principally to the Organization of the Petroleum Exporting Countries’ (OPEC) “Arab Oil Embargo” (1973–1974) and the Iranian revolution (1979), when global oil supplies became threatened and costs rose steeply. Two subsequent Gulf Wars (1991 and 2003) highlighted the dangerous geo-political dimensions of Middle-Eastern oil
hand in the fight against resistant microbes. This thesis discusses the feasibility and potential of specific immunotherapy in treating acute bacterial infections and chronic sequels. The infection model is acute cystitis; the most common form of urinary tract infection, affecting millions of patients annually. Susceptible patients develop the characteristic clinical manifestation of dysuria, urge
Background: Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking.Methods: Google's Inception v4 CNN architecture was trained and validated using dermoscopic images and corresponding diagnoses. In a comparative cross-sectional reader study a 100-image test-set was used (l
Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training and test set. We trained SSPs for subtypes and ROR assigned by nearest-centroid (NC) methods and SSPs
BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:
Aims: Pre-capillary pulmonary hypertension (PHpre-cap) has a poor prognosis, especially when caused by pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc-PAH). Whether cardiac magnetic resonance (CMR)-based quantification of atrial volumes in PHpre-cap is beneficial in risk assessment is unknown. The aims were to investigate if (i) atrial volumes using CMR are associated
I syfte att utvärdera effekten av dubbdäcksförbudet på Friggagatan med avseende på luftkvaliteten har Miljöförvaltningen i Göteborg på uppdrag av trafikkontoret i Göteborg utfört luftkvalitetsmätningar på Friggagatan mellan 2013-01-01 och 2013-09-30. Dessutom utförde Miljöförvaltningen mätningar av dubbdäcksanvändningen på Friggagatan, vid Drottningtorget och i Haga. Vidare användes även mätdata f
Popular Abstract in Swedish Avhandlingens huvudsakliga syfte är att utforska unga kvinnors levda erfarenheter av en kropp som å ena sidan betraktas som avvikande – den fysiskt funktionsnedsatta eller rörelsehindrade kroppen – å andra sidan betraktas som presterande – den idrottande kroppen. De frågor som ställs i avhandlingen är hur de unga kvinnorna förhandlar de båda subjektspositioner som uppstThe main aim of this thesis is to explore young women’s lived experience of the body, which, on one hand, is viewed as deviant – the disabled body – and, on the other hand, is viewed as accomplished – the sporting body. The questions posed in the thesis are the following: how do the young women handle the two subject positions that emerge as a result of the perception of them as respectively devia
Abstract This essay will examine if there is a possibility that the Millennium Development Goal number 3 (MDG 3) can be achieved by year 2015 in Bangladesh. Therefore, an examination will be performed of the report The Millennium Development Goals, Bangladesh Progress Report 2011. Focus will be on MDG 3 which aims on promoting gender equality and women’s empowerment for instance in Bangladesh. In
Miljöbalkens hushållningsregler syftar till att ur ett långsiktigt perspektiv säkra tillgången till viktiga mark- och vattenresurser genom ett ändamålsenligt utnyttjande. Företräde ska ges användning som medför en från allmän synpunkt god hushållning. Flera typer av intressen har pekats ut som särskilt skyddsvärda ur ett hushållningsperspektiv, kulturmiljön är ett av dessa. För kulturmiljöer som bThe Basic provisions concerning the management of land and water areas in The Swedish Environmental Code aim to secure the long-term access to important resources by utilizing them in the most appropriate ways. Priority shall be given to use that promotes good management from the point of view of public interest. A number of resources of particular importance have been pointed out, one of these ar
Det är känt inom den typologiska lingvistiken att spatial rörelse uttrycks på olika sätt på olika språk. På svenska uttrycks ofta en rörelses sätt i verbroten och dess riktning i en till verbet knuten satellit (S-språk), då franskan vanligtvis däremot uttrycker rörelsens riktning i verbroten och utelämnar dess sätt (V-språk). Svensktalande föredrar i en given situation ett uttryck som en uggla komIt is well known within typological linguistics that the expression of motion is language-specific. In Swedish the manner of a motion is typically expressed in a verb while the path of motion is expressed in a satellite connected to the verb (S- languages), whereas, in French, typically the path of motion is expressed in the verb and the manner is omitted. This explains why speakers of Swedish see
Purpose: This study explores how people account for their translation, negotiation and shaping of environmentally relevant practices as information practices in their everyday life during the holidays and asks further how these narratives can be seen as accounting for situated information practices. It focuses on how summer guests holidaying in southern Sweden talk about how they connect different
As the most figurative asset of membership in a majority or minority and the most symbolic aspect of national authority, language is a major site of struggle for majority power and minority resistance. For the purposes of this study, which focuses on the question of Kurdish linguistic rights in Turkey, the sites of struggle for majority power and minority resistance are as follows: the documents o
