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The synthesis and characterization of twenty new pentamethylcyclopentadienyl-rhodium and iridium complexes containing N^N and N^O-chelating chloroquine analogue ligands are described. The in vitro antimalarial activity of the new ligands as well as the complexes was evaluated against the chloroquine sensitive (CQS) NF54 and the chloroquine resistant (CQR) Dd2 strains of Plasmodium falciparum. The

Fungus-growing (attine) ants and their fungal symbionts passed through several evolutionary transitions during their 50 million year old evolutionary history. The basal attine lineages often shifted between two main cultivar clades, whereas the derived higher-attine lineages maintained an association with a monophyletic clade of specialized symbionts. In conjunction with the transition to speciali

Studies from the public health and epidemiologic fields consider self-assessment of health as a solid measure of general health due to its predictive ability in relation to mortality. Empirical evidence in this direction have justified the generalized use of this measure in health surveys as well as its application to the general population. However, it is important to evaluate whether these findi

SPECT projections are contaminated by scatter, resulting in reduced image contrast and quantitative errors. When tissue is present behind the source, some of the detected photons backscatter via this tissue. Particularly in dual-isotope SPECT and in combined emission-transmission SPECT, backscatter constitutes a major part of the down-scatter contamination in lower-energy windows. In this paper, t

The paper presents a fed-batch fermentation technique for bioreactors operating close to their maximum oxygen transfer capacity. The method combines the advantages of the probing feeding strategy and the temperature limited fed-batch technique. When the maximum oxygen transfer capacity of the reactor is reached, the temperature is decreased to lower the oxygen demand. To achieve a good control of

Crosslinking of small heat-shock proteins (sHsps) by tissue transglutaminase (tTG) is enhanced by stress and under pathological conditions. We here used hexapeptide probes to determine the amine donor (K) and acceptor (Q) sites for tTG in Hsp20. Mass spectrometric peptide mass fingerprinting and peptide fragmentation established that Q(31) and the C-terminal K-162 are involved in inter- and intram

Om hur illustratörer framställt den litterära gestalten "Falstaff, fakir". Utgör förkortad bearbetning av artikeln med samma titel i Fakirenstudier XIV (1999).

Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of

The identification of the regions where vector-borne diseases are transmitted is essential to study transmission patterns and to recognize future changes in environmental conditions that may potentially influence the transmission areas. SGS1, one of the lineages of Plasmodium relictum, is known to have active transmission in tropical Africa and temperate regions of Europe. Nuclear sequence data fr

Rheumatoid arthritis (RA) that is negative for anticitrullinated protein antibodies (ACPA) is a subentity of RA, characterized by less severe disease. At the individual level, however, considerable differences in the severity of joint destruction occur. We performed a study on genetic factors underlying the differences in joint destruction in ACPA-negative patients.

Clavulanic acid is a beta-lactamase inhibitor used in therapeutic combinations with the penicillin-type antibiotics. During the fermentation leading to clavulanic acid, a succinyl L-tyrosine by-product is unavoidably formed. Occasionally, the amount of this by-product is found to be as high as 2% of the product even after standard purification operations. To further remove this impurity, we prepar

The effect of using different binding agents in combination with hemp shives and fibres in Lime-Hemp Concrete (LHC) building material was examined. LHC is a light composite building material with building lime as binding agents and hemp (Cannabis sativa) as a renewable raw material from agriculture. Contemporary LHC only uses the woody core part of the hemp, the shive. However, using both hemp shi

Background: Over the last 20 years stress at work has been found to be predictive of several conditions such as coronary heart disease, high blood pressure and non- specific sick leave. The Karasek demand/ control/ strain concept has been the most widely used in prospective epidemiological studies. Objectives: To describe distribution in Karasek's demand/ control ( DC) dimensions as well as preval

In this paper we extend the eliminant construction of Burchnall and Chaundy for commuting differential operators in the Heisenberg algebra to the q-deformed Heisenberg algebra and show that it again provides annihilating curves for commuting elements, provided q satisfies a natural condition. As a side result we obtain estimates on the dimensions of the eigenspaces of elements of this algebra in i

Atrial fibrillatory rate (AFR) can predict outcome of interventions for atrial fibrillation (AF); however, AFR behavior at AF onset in humans is poorly described. We studied AFR during spontaneous AF episodes in patients with lone paroxysmal AF who received implantable loop recorders and had AF episodes of 1 hour or more recorded (n=4). Mean AFR per minute was assessed from continuous implantable

Securing access to land around the world is an issue that pervades many development agendas. Often promoted through legal and administrative systems, secure land tenure is used in the battle against poverty and to reduce land based conflict. Conceptualizations of secure tenure tend to differ between international institutions and academia. This thesis aims to understand how the World Bank concept

This thesis explores the discursive depiction of life in Portugual from the perspective of lifestyle migrants and digital nomads on TikTok. The aim of this thesis is to uncover the motivations of foreigners to live in Portugal, lifestyle migrants’ integration into Portuguese society, and their acknowledgement of the growing gentrification issues in Portugal. The method used in this study is Norman

The idea of Chile as a “miracle” of neoliberal reform has been extensively confronted since October of 2019 in a large wave of protests throughout the country, by a vast majority feeling excluded from its benefits. Despite this conflict (known as the “Estallido Social”, or “Social Outbreak”) occurring exclusively in cities, previous analyses do not explicitly address the role of urban space in thi