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Downstream regulatory element antagonist modulator (DREAM)/potassium channel interacting protein (KChIP3) is a multifunctional protein of the neuronal calcium sensor subfamily of Ca2+-binding proteins with specific roles in different cell compartments. In the nucleus, DREAM acts as a Ca2+-dependent transcriptional repressor, and outside the nucleus DREAM interacts with Kv4 potassium channels, regu
Forskning kring tidigt liv möter svårigheter utöver de som forskning kring senare liv ställs inför. På grund av att de tidigaste bergarterna inte finns bevarade har viktig information om jordens tidiga förhållanden för evigt gått förlorad. Dessutom var de tidigaste livsformerna små och morfologiskt enkla, vilket betyder att abiotiska pseudofossil lätt kan infiltrera fossilarkivet. Ett centralt tem
Conducted between the months of January and March 2012 in Eldoret Kenya, this study sought to find out why the internally displaced women of Yamumbi IDP Camp A remained trapped in the displacement camp. The study sought the opinions and views of the women. By applying qualitative approach method of semi-structured interviews and focus group discussions hand-recorded data was collected. Using purpo
Konklusionen i uppsatsen är att skatteflykt utgör möjligheten att genom gränsöverskridande transaktioner minimera sin skatt genom nyttjande av skattekonkurrens mellan jurisdiktioner. Hur skatteflykt bedöms juridiskt skiljer sig åt mellan EU-rätten, som anser att om substans i etablering föreligger är skatteflykt ett legalt nyttjande av etableringsfriheten och svensk rätt, som ser till rättshandlinThe essay concludes that tax evasion is the possibility through cross-border transactions minimize taxes through use of tax competition between jurisdictions. How avoidance and evasion is legally jugded differs between EU law, that statues if substance in establishment exists is tax evasion or avoidance a legal exercise of the right of establishment, and the Swedish law, which refer to legal docum
The aim of this project was to investigate the effect of Lactobacillus plantarum 299v on the flocculating behaviour of beer starter culture yeast strains isolated from both top and bottom fermenting yeasts from a previous study (Li.Yu.,2014 unpublished). In the present study,microbial enumeration was done through basic culturing and plating techniques. Yeast strains and isolates of Lactobacillus p
The mining industry is characterized by a hazardous working environment for its employed blue-collar workers and a general complexity of valuation for investors. By theories of behav-ioral finance, corporate social responsibility, and others outlined in the following, this makes a setting where one could plausibly expect reactions and even overreactions among investors to fatal accidents incurred
The war in Ukraine has made the issue of energy poverty salient again in Germany after a long period of political neglect and limited attention. In studying the issue, I bridged agency and structure by employing Hajer’s Argumentative Discourse Analysis to examine both discourse coalitions and their storylines between 2017 and early 2022. I examined the discursive mechanisms behind the marginalizat
The Swedish ministry of education recently voiced intentions to uproot over a decade's worth of digital implementation in the classroom, on the back of falling PISA results and increasing reports of learning difficulties. Empirical evidence for either positive or negative effects on learning stemming from computer usage is scarce and inconclusive. Utilizing a fixed effects model that exploits
The androgen receptor is a key transcription factor contributing to the development of all stages of prostate cancer (PCa). In addition, other transcription factors have been associated with poor prognosis in PCa, amongst which c-Myc (MYC) is a well-established oncogene in many other cancers. We have previously reported that the AR promotes glycolysis and anabolic metabolism; many of these metabol
Arbetet syftar till att undersöka hur en domstol kan gå tillväga i bevisvärderingen av sakkunnigbevisning när det finns motstridig sådan och hur en sådan bevisvärdering förhåller sig till robusthetskravet. Robusthet är ett mått på sannolikheten att ett bevisfaktums stöd för ett tema förändras vid ytterligare utredning. Med utgångspunkt i en deskriptiv del av arbetet, där bevisrättsliga principer The thesis’ purpose is to examine how a court of law can evaluate expert testimony when both the prosecutor and the defense have called experts who give contrary statements. The examined evidence evaluation is thereafter analyzed with regards to the notion of robustness in evidence. Robustness is a way of measuring the probability that additional evidence will alter the probability based on the ex
Russia has been issuing passports to Eastern Europe and the South Caucasus since the Soviet dissolution. Most targeted are secessionist regions of former Soviet states, whose populations are now becoming Russian due to passportisation. This has had several effects on the Eastern Neighbourhood, including brain drain, meaning that the highly educated and skilled citizens are emigrating. The brain dr
This thesis looks at the Nordic Centre for Gender in Military Operations and sees how the centre constructs its own identity to align with the discourse of postna¬tional defense, and how it evaluates NATOs peacekeeping operation in Afghani¬stan. Through this, the thesis aims to analyse the hegemonic struggle between the discourses of traditional military structure and the cosmopolitan postnational
The American company town has, by several authors, been pronounced dead in its current state. In this study, the concept of the company town is applied to the United Nations Headquarters in New York City. When applying the concept of the company town in a contemporary context, the exact pattern that characterised the company town during the 19th and early 20th century cannot be followed. By making
Economic growth research has over the past few decades tried to explain what causes coun-tries to achieve a sustainable economic growth. Many theories and hypotheses’ have been introduced and tried empirically. One key factor that has proven to create growth is the tech-nological progress. But what is technology? It is a very complex concept and in this paper we use panel data for 41 countries ove
The lifetimes of low-lying excited states below the 8+ seniority isomer were directly measured using fast timing detectors in the neutron-deficient isotopes 98,100Cd. This experiment was conducted with the DEcay SPECtroscopy (DESPEC) setup at GSI, where the ions of interest were produced via a fragmentation reaction and identified using the FRagment Separator (FRS) before being implanted in the AI
