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FORSKARNAS NYHETER Kunglig glans när 42 forskare belönades 2 0 1 3 - 1 4 S V E N S K A S Ä L L S K A P E T F Ö R M E D I C I N S K F O R S K N I N G • G R U N D A T 1 9 1 9 S S M F . S E Drottning Silvia delade personligen ut diplomen till de sex unga forskare som tilldelades anslag som SSMF-forskare. Här får Fang Fang från Karolinska Institutet sitt diplom. Efter prisutdelningen var det mingel i
Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung
Background: Colon capsule endoscopy (CCE) represents a noninvasive technology that allows visualization of the colon without requiring sedation and air insufflation. A second-generation colon capsule endoscopy system (PillCam Colon 2) (CCE-2) was developed to increase sensitivity for colorectal polyp detection compared with the first-generation system. Objective: To assess the feasibility, accurac
This thesis investigates how suicide is portrayed in japanese films and if it is glorified or not. Two films have been chosen for analysis, Seppuku (Harakiri, Masaki Kobayashi, 1962) and Jisatsu saakuru (Suicide Club/Circle, Shion Sono, 2001). The purpose of the thesis is to find out if suicide is glorified in these two films and to examine the historical and reality connections of the timeperiods
The response of tundra plants to enhanced UV-B radiation simulating 15 and 30% ozone depletion was studied at two high arctic sites (Isdammen and Adventdalen, 78 degrees N, Svalbard).The set-up of the UV-B supplementation systems is described, consisting of large and small UV lamp arrays, installed in 1996 and 2002. After 7 years of exposure to enhanced UV-B radiation, plant cover, density, morpho
Background The European Randomized Study of Screening for Prostate Cancer was initiated in the early 1990s to evaluate the effect of screening with prostate-specific-antigen (PSA) testing on death rates from prostate cancer. Methods We identified 182,000 men between the ages of 50 and 74 years through registries in seven European countries for inclusion in our study. The men were randomly assigned
This study reports carbon and water fluxes between the land surface and atmosphere in eleven different ecosystems types in Sub-Saharan Africa, as measured using eddy covariance (EC) technology in the first two years of the CarboAfrica network operation. The ecosystems for which data were available ranged in mean annual rainfall from 320 mm (Sudan) to 1150 mm (Republic of Congo) and include a spect
At ISOL ( Isotope Separator On-Line) facilities, which utilize thick primary production targets, beams of neutron-rich iron isotopes are dificult to obtain due to the long extraction time of these isotopes out of the target matrix. At REX-ISOLDE, an exploratory experiment was carried out to investigate the possibility of producing a post-accelerated beam of neutron-rich iron isotopes by the in-tra
Odd-parity core excited states have been identified in two close neighbors of Sn-100: Pd-96 and Ag-97. This was done in an fusion-evaporation experiment, using a Ni-58 beam on a Sc-45 target. Even-parity core excited states in these nuclei are very well reproduced in large scale (LSSM) calculations in which particle-hole excitations are allowed with up to five g(9/2) protons and neutrons across th
Objectives To perform fine mapping of the autoimmunity susceptibility gene BLK and identify functional variants involved in systemic lupus erythematosus (SLE). Methods Genotyping of 1163 European SLE patients and 1482 controls and imputation were performed covering the BLK gene with 158 single-nucleotide polymorphisms. Logistic regression analysis was done using PLINK and conditional analyses usin
Here for the first time, we detail self-contained (wireless and self-powered) biodevices with wireless signal transmission. Specifically, we demonstrate the operation of self-sustained carbohydrate and oxygen sensitive biodevices, consisting of a wireless electronic unit, radio transmitter and separate sensing bioelectrodes, supplied with electrical energy from a combined multi-enzyme fuel cell ge
Research on ecosystem services has grown rapidly over the last decade. Two conceptual frameworks have been published to guide ecological assessments of organisms that deliver services-the concepts of service-providing units (SPUs) and ecosystem service providers (ESPs). Here, we unite these frameworks and present an SPU-ESP continuum that offers a coherent conceptual approach for synthesizing the
In this article we reflect on the quality of a realist synthesis paradigm applied to the evaluation of Phase V of the WHO European Healthy Cities Network. The programmatic application of this approach has led to very high response rates and a wealth of important data. All articles in this Supplement report that cities in the network move from small-scale, time-limited projects predominantly focuse
To analyse the differences between patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) entered into randomised clinical trials (RCTs) and those followed in large observational cohorts.
Previously, a healthy Nordic diet (ND) has been shown to have beneficial health effects close to those of Mediterranean diets.
Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor, platelet-derived growth factor receptor, and fibroblast growth factor receptor, has shown activity in phase 2 trials in this setting. We investigated the combination of nintedanib with standard carboplatin and paclitaxel chemotherapy in patients with newly diagnosed advan
Background Type 1 diabetes (T1D) is a cell-mediated autoimmune disease characterized by destruction of the pancreatic islet cells. The use of cryopreserved cells is preferable to the use of freshly isolated cells to monitor clinical trials to decrease assay and laboratory variability. Methods The T-Cell Workshop Committee of the Immunology of Diabetes Society compared two widely accepted T-cell fr
