Search results

Uppsatsmall Lunds universitet STV102 Statsvetenskapliga institutionen VT04 Handledare: NN Depoliticizing feminism? The transformation of an ideology-charged concept in a nation branding context ISABELLE KARLSSON Lund University Department of strategic communication Master’s thesis Course: SKOM12 Term: Spring 2018 Supervisor: Cecilia Cassinger Examiner: Åsa Thelander 2 Abstract Depoliticizing femin

https://www.isk.lu.se/sites/isk.lu.se/files/thesis-isabelle-karlsson_depoliticizing-feminism.pdf - 2026-06-08

Background: Whether disease burden in patients with metastatic castration-sensitive prostate cancer (mCSPC) predicts treatment outcomes is unknown. We assessed apalutamide treatment effect in TITAN patients with mCSPC by disease volume, metastasis number and timing of metastasis presentation. Methods: These protocol-defined and post hoc analyses of the phase III randomised TITAN study evaluated cl

pnas201105135 1..6 Direct conversion of human fibroblasts to dopaminergic neurons Ulrich Pfisterer1, Agnete Kirkeby1, Olof Torper1, James Wood, Jenny Nelander, Audrey Dufour, Anders Björklund, Olle Lindvall, Johan Jakobsson, and Malin Parmar2 Departments of Experimental Medical Science and Clinical Sciences, Wallenberg Neuroscience Center, and Lund Stem Cell Center, Lund University, SE-221 84 Lund

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/pnas-2011-pfisterer-1105135108.pdf - 2026-06-08

Background: Episodic memory decline is a hallmark of Alzheimer's disease (AD). Subjective memory complaints (SMCs) may represent one of the earliest signs of impending cognitive decline. The degree to which self- or partner-reported SMCs predict cognitive change remains unclear. Objective: We aimed to evaluate the relationship between self- and partner-reported SMCs, objective cognitive performanc

INTRODUCTION: It is unclear how different proteinopathies (tau, transactive response DNA-binding protein 43 [TDP-43], amyloid β [Aβ], and α-synuclein) contribute to atrophy within medial temporal lobe (MTL) subregions in Alzheimer's disease (AD).METHODS: We utilized antemortem structural magnetic resonance imaging (MRI) data to measure MTL substructures and examined the relative contribution of ta

Introduction: Thrombocytopenia is frequent in intensive care unit (ICU) patients and has been associated with worse outcome. Platelet transfusions are often used in the management of ICU patients with severe thrombocytopenia. However, the reported frequencies of thrombocytopenia and platelet transfusion practices in the ICU vary considerably. Therefore, we aim to provide contemporary epidemiologic

Background: The filaggrin gene (FLG) plays a role in skin diseases, with the skin barrier function being impaired in FLG null carriers. The role of FLG status in relation to nickel penetration into the skin remains unclear. Objectives: To elucidate the association between FLG status and nickel penetration into stratum corneum (SC) in individuals without self-reported history of nickel allergy. Met

Background Despite well-established guidelines for managing major depressive disorder, its extensive disability burden persists. This Value of Treatment mission from the European Brain Council aimed to elucidate the nature and extent of gaps between best-practice and current-practice care, specifically to: 1. Identify current treatment gaps along the care pathway and determine the extent of these

IntroductionSmall bowel obstruction, infertility, and chronic abdominal pain are generally mentioned as the main clinical consequences of adhesion formation after abdominal surgery1,2. Difficulties experienced during reoperation are less pronounced consequences, but seem to have a huge impact. A large retrospective cohort study3 revealed that adhesiolysis was significantly associated with risk of

Objective: To investigate the association between personal history, anthropometric features and lifestyle characteristics and endometrial malignancy in women with abnormal vaginal bleeding. Methods: Prospective observational cohort assessed by descriptive and multivariable logistic regression analyses. Three features—age, body mass index (BMI; calculated as weight in kilograms divided by the squar

Morphologic and immunohistochemical analysis of preoperative core needle biopsies (CNB) is important in the management of patients with soft tissue and bone tumors (STBTs). Most SBTB subtypes have more or less extensive DNA copy number aberrations (CNA), potentially providing useful diagnostic information. To evaluate the technical feasibility of single nucleotide polymorphism (SNP) array analysis

Background: Immune checkpoint inhibitors are now a part of the treatment arsenal for triple-negative breast cancer (TNBC) but refinement of PD-L1 as a prognostic and predictive biomarker is a clinical priority. We aimed to evaluate the relevance of novel PD-L1 immunohistochemical (IHC) thresholds in TNBC with regard to PD-L1 gene expression, prognostic value, tumor infiltrating lymphocytes (TILs),

4MOST is a new high-multiplex, wide-field spectroscopic survey facility under construction for ESO's 4m-VISTA telescope at Paranal, Chile. Its key specifications are: a large field of view of 4.4 square degrees, a high multiplex fibre positioner based on the tilting spine principle that positions 2436 science fibres in the focal surface of which 1624 fibres go to two low-resolution optical spectro

The field of organ transplantation is experiencing a transformative shift with the rise of Advanced Therapy Medicinal Products (ATMPs), which include gene therapies, somatic cell therapies, and tissue-engineered products. These therapies offer new, potentially curative treatments for longstanding medical challenges, impacting numerous patients. However, their adoption is hindered by complex regula

Importance: Accurate risk prediction of morbidity and mortality in patients with heart failure with preserved ejection fraction (HFpEF) may help clinicians risk stratify and inform care decisions. Objective: To develop and validate a novel prediction model for clinical outcomes in patients with HFpEF using routinely collected variables and to compare it with a biomarker-driven approach. Design, Se

Cells continuously sense external forces from their microenvironment, the extracellular matrix (ECM). In turn, they generate contractile forces, which stiffen and remodel this matrix. Although this bidirectional mechanical exchange is crucial for many cell functions, it remains poorly understood. Key challenges are that the majority of available matrices for such studies, either natural or synthet

Halite (NaCl mineral) has exhibited the potential to preserve microorganisms for millions of years on Earth. This mineral was also identified on Mars and in meteorites. In this study, we investigated the potential of halite crystals to protect microbial life-forms on the surface of an airless body (e.g., meteorite), for instance, during a lithopanspermia process (interplanetary travel step) in the

Excited states in [Formula Presented]Sb have been identified for the first time in a series of [Formula Presented]-spectroscopy experiments using both thin and backed targets, including neutron-fold and recoil-mass measurements to provide unambiguous channel identification. The three decoupled intruder bands observed in [Formula Presented]Sb are based upon configurations involving 2p-2h excitation

Filaggrin (FLG), a skin barrier protein, is associated with higher dermal uptake of some chemicals in carriers of loss-of-function (null) mutations. This study investigates FLG mutations and systemic effects following dermal exposure to chemicals. Individuals (n = 23 FLG null, n = 31 FLG wt) were simultaneously exposed to pyrimethanil, pyrene, oxybenzone, and nickel ions for 4 h. Pre- and post-exp

Studien är en första utvärdering i Sverige av X-bandsteknik som väderradar. Den visar hur flera X-bandsradaranläggningar kan samarbeta och hur regninformationen kan användas för avrinningssimulering. Tekniken öppnar nya utvecklingsmöjligheter för VA-branschen. Det gäller inte minst driften av ledningsnätet, väderstyrning av ledningsnät och reningsverk, samt utvecklingen av publika varningssystem.In this research report, a new methodology has been developed in order to integrate several X-band radar data sets in to one complete set. Furthermore, a direct and an indirect evaluation have been conducted compared to stationary rain gauges and C-band radar. In the indirect analysis, the input data sets were integrated into runoff models for Ellinge and Lundåkra WWTP where the results were compa