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Enzymes are involved in most reactions in nature. They are important both for the understanding of biological life and for reactions of industrial interest, e.g. in the production of artificial fertilizers, the production of biomass or biofuels. Enzymes with one or several metal ions are called metalloenzymes. In this thesis we study three different metalloenzymes, nitrogenase, lytic polysaccharid

Background: Despite uniform operating techniques, lack of fusion still occurs after ankle arthrodesis. Differences in the biological healing potential may be a factor but the mechanical performance of the arthrodesis construct because of varying bone quality also may be important. Internal compression techniques are preferred because of higher union rates, shorter fusion times, and fewer complicat

In circumpolar regions, coastlines offer rich constellations of diverse resources, and have long been a focus of human habitation. Despite the rich archaeological records that are located along many northern coastlines, there is a relatively limited understanding of the range of factors that informed local settlement strategies. Northern Norway has one of the world’s longest and best-preserved arc

The Cherenkov Telescope Array (CTA), will be the major global observatoryfor very high-energy (VHE) gamma-ray astronomy over the next decadeand beyond. The scientific potential of CTA is extremely broad: fromunderstanding the role of relativistic cosmic particles to the search for darkmatter. CTA is an explorer of the extreme universe, probing environmentsfrom the immediate neighbourhood of black

Exposure to low temperatures requires an organism to overcome physiological challenges. New Zealand wētā belonging to the genera Hemideina and Deinacrida are found across a wide range of thermal environments and therefore subject to varying selective pressures. Here we assess the selection pressures across the wētā phylogeny, with a particular emphasis on identifying genes under positive or divers

Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen available to plants (although the enzyme itself is strictly microbial). It has been studied extensively with both experimental and computational methods, but many details of the reaction mechanism are still unclear. X-ray crystallography is the main source of structural information for biomacromolecules, but it h

We have calculated redox potentials of 12 blue copper protein sites comparing 64 computational methods, systematically varying the quantum mechanics (QM) system size, dielectric constants, density functional, and basis sets. All methods were based on structures optimized with combined QM and molecular mechanics (QM/MM) approaches. The redox potentials were evaluated using 10 quality metrics. The b

Kombination av läkemedel kan hjälpa blödarsjuka – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kombination av läkemedel kan hjälpa blödarsjuka 2013-04-11 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Genom att kombinera två olika typer

https://www.vetenskaphalsa.se/kombination-av-lakemedel-kan-hjalpa-blodarsjuka/ - 2026-07-03

Mer om BioFINDER-studien – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Mer om BioFINDER-studien 2015-05-08 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Här hittar du tre fördjupande artiklar om BioFINDER-studien. (tillbaka till De vi

https://www.vetenskaphalsa.se/mer-om-biofinder-studien/ - 2026-07-03

”Jag hade nog tur som fick så bra information” – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök ”Jag hade nog tur som fick så bra information” 2016-06-01 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Rolf Lindstrup tycker att få tidig in

https://www.vetenskaphalsa.se/jag-hade-nog-tur-som-fick-sa-bra-information/ - 2026-07-03

Ny upptäckt förklarar symtom före danssjuka – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ny upptäckt förklarar symtom före danssjuka 2010-09-09 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Huntingtons sjukdom kopplas oftast samman m

https://www.vetenskaphalsa.se/ny-upptackt-forklarar-symtom-fore-danssjuka/ - 2026-07-03

Cancer is one of the main causes of death in the world, particularly in developing countries and is considered as a major public health problem. Radiation therapy has been an important modality for treatment of cancer for many decades. It can be used as a sole treatment modality or in combination with for example surgery, chemotherapy, hormone therapy and/or immune therapy. It has been calculated

År 1926 färdigställde Processkommissionen sitt principbetänkande angående rättegångsbalkens ombildning. Kommissionen föreslog en form av förenklat förfarande, där enklare mål skulle kunna lagföras utanför domstolen. Den största anledningen till att ett enklare och snabbare förfarande ansågs behövas var för att avlasta domstolarna från en allt för tung arbetsbörda. Snabbspolat framåt, så reglerasIn 1926 a commission report about a new code of judicial procedure was completed. The commission suggested the introduction of a summary procedure for misconducts that did not need to be resolved by the court. The main reason for this procedure was that it would unburden the courts from a heavy workload. Fast forward to today, the summary procedure, penal order, is regulated in chapter 48 of the

Parallellt med den rådande Covid-19 pandemin råder en annan ”skuggpandemi” bakom stängda dörrar. Våld i hemmet har allt för länge varit ett nedprioriterat diskussionsämne och hur uppmärksammas våld som sker i det gömda och vilka är de ekonomiska, sociala och politiska konsekvenserna? I en rapport från kvinnojouren Unizon redovisas det att mäns våld mot kvinnor har ökat under pandemin och att en f

Microsoft Word - 8655F43796B93E8662A613C2DCC1C3EE.docx COSM30 Data Collection and Analysis Literature List Course director and main teacher: Nicholas Loubere Total Pages: 807 Required Reading List Bryman, Alan. 2016. Social Research Methods. Oxford: Oxford University Press. 5th ed. Chapters 7, 8, 9, 10, 11, 12, 23, 26, and 27. • Number of pages: 198 • Price: 487 kr Crawford, Gordon, Lena J. Krucke

https://www.ace.lu.se/sites/ace.lu.se/files/2023-05/COSM30_Literature_2023.pdf - 2026-07-04

Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen available to organisms. The detailed mechanism of this enzyme is currently not known, and computational studies are complicated by the fact that different density functional theory (DFT) methods give very different energetic results for calculations involving nitrogenase models. Recently, we designed a [Fe(SH)4H]

Land remediation is an important part of restoration measures after a radioactive fallout containing long-lived fission products such as 137Cs. In this multidisciplinary study, we focused on three main issues related to remediation of contaminated urban areas. First, we assessed how much decontamination contributes to reducing resident radiation exposure and how much this reduction depends on the