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Activated protein C resistance due to a common factor V gene mutation is a major risk factor for venous thrombosis

Inherited resistance to activated protein C (APC) was recently discovered to be a cause of familial thrombophilia and is now known to be the most common genetic risk factor for venous thrombosis. It is caused by a single point mutation in the gene for factor V, which predicts substitution or arginine (R) at position 506 with a glutamine (Q). Accordingly, the activated form of mutated factor V (FVa

Familial risks for chronic obstructive pulmonary disease among siblings based on hospitalisations in Sweden

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive disabling condition, for which tobacco smoking, environmental pollution, inherited alpha-antitrypsin deficiency and their interactions are predisposing factors. We carried out a family study on COPD in order to address the role of heritable and environmental risk factors at a population level.METHODS: In a nationwide study o

Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

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In this article we review the legal regulation of an obligation to self-isolate in Ukraine. For the period from 22 April 2020 till 22 June 2020 four groups of persons were obliged to self-isolate due to COVID-19. These groups are: persons diagnosed with or suspected to have COVID-19, persons that have been in contact with those diagnosed with COVID-19, those who consented to self-isolation when en

Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171

Culture conditions in which hematopoietic stem cells (HSCs) can be expanded for clinical benefit are highly sought after. Here, we report that inhibition of the epigenetic regulator Lysine-specific histone demethylase 1A (LSD1) induces a rapid expansion of human cord blood derived CD34+ cells and promotes in vitro propagation of long-term repopulating HSCs by preventing differentiation. The phenot

Interoperability in EU Competition Law: Rethinking the Essential Facilities Doctrine for Digital Platforms after Android Auto

Denna uppsats undersöker hur EU:s konkurrenslagstiftning reglerar interoperabilitetsskyldigheter för dominerande digitala plattformar. Uppsatsen visar hur EU-domstolens avgörande i Android Auto (C-233/23) omformar teorin om nödvändiga nyttigheter (Essential Facilities Doctrine, EFD) som etablerades i Bronner-domen (C-7/97). Vidare analyseras denna framväxande doktrins samspel med de interoperabiliThis thesis explores how EU competition law governs interoperability obligations for dominant digital platforms. It shows how the CJEU’s judgment in Android Auto (C-233/23) redefines the Essential Facilities Doctrine (EFD) established in Bronner judgment (C-7/97) and how this emerging doctrine interacts with the interoperability obligations introduced by the Digital Markets Act (DMA). The Android

Benign Tumours of the Small Bowel

Benign tumours of the small intestine consist of various rare entities such as tumour-like inflammatory or hyperplastic lesions, hamartomas (organoid malformations), ectopic tissues, and true neoplasms of epithelial or mesenchymal origin. These benign tumours often stay asymptomatic for years, with small lesions frequently remaining undiscovered. They may be manifested clinically by bleeding, iron

Verksamhetsplan-resursfordelning-2025-webb

Verksamhetsplan och resursfördelning 2025 NATURVETENSKAPLIGA FAKULTETEN 1 Verksamhetsplan och resursfördelning | Naturvetenskapliga fakulteten 2025 DNR STYR 2024/2634 Innehåll Inledning ................................................................................................................................... 3 Utbildning på grund och avancerad nivå .........................................

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2024-12/verksamhetsplan-resursfordelning-2025-webb.pdf - 2026-05-26

Investigating Agency: Methodological and Empirical Challenges

The literature on regional development increasingly recognizes that agency is an essential but understudied factor in processes of regional structural change. However, much like the fundamental debates in social sciences about agency and structure, work in this field has often remained theoretical. Investigating the role of agency in regional economic development, systematically and at the micro-l

Enacting biochar as a climate solution in Denmark

Following the Paris Agreement's climate targets and the modelling community's scenarios of how to reach them, carbon dioxide removal is gaining increasing importance in national climate policies. This is also the case in Denmark – considered by itself and others a climate frontrunner – where biochar is envisioned to cover 10% of the 2030 reduction goal. However, apart from research experiments and

Rummen i biblioteksrummet : perspektiv på bibliotekslokalens anpassning

In this master's thesis I will study library space in its practical use in relation to the professionals working in it daily, i.e. the library staff. It seems that this profession should have a unique knowledge base around how the library is used and how space can be organised to benefit the users, the staff and the collections. The library is closely connected to and affected by society and s

Two odometers in honeybees?

Although several studies have examined how honeybees gauge and report the distance and direction of a food source to their nestmates, relatively little is known about how this information is combined to obtain a representation of the position of the food source. In this study we manipulate the amount of celestial compass information available to the bee during flight, and analyse the encoding of s

DARKLab Collaborates with Tharros Project to Revolutionize Archaeological Data Sharing

DARKLab Collaborates with Tharros Project to Revolutionize Archaeological Data Sharing DARKLab Collaborates with Tharros Project to Revolutionize Archaeological Data Sharing Published 8 July 2024 We are excited to announce that DARKLab is collaborating with the Tharros Project, led by the University of Cincinnati, under the direction of Prof. Steven Ellis, with field operations overseen by Prof. E

https://www.darklab.lu.se/article/darklab-collaborates-with-tharros-project-to-revolutionize-archaeological-data-sharing/ - 2026-05-04

Mindfulness lika bra som KBT vid ett brett spektrum av psykiatriska symtom

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. Mindfulnessterapi i grupp har en lika positiv effekt som individuell KBT (kognitiv beteendeterapi) vid behandling av en omfattande spännvidd av psykiatriska symtom hos patienter med depression, ångest och stress-relaterade besvär. Det visar en ny forskningsstudie från Centrum för primärvårdsforskning i Malmö som är

https://www.lu.se/artikel/mindfulness-lika-bra-som-kbt-vid-ett-brett-spektrum-av-psykiatriska-symtom - 2026-05-25

Kemiforskare har tillverkat sfärformade lysdioder tack vare enkel ångreaktion

Forskare vid Lunds universitet har lyckats tillverka storskaliga och sfärformade LED-ytor vilket tidigare har varit en teknisk utmaning. Experimentet, som möjliggjordes av en enkel kemisk reaktion, kan bli avgörande för en betydligt billigare produktion av lysdioder. Perovskit är ett medelhårt mineral som upptäcktes i Uralbergen 1839 och tillhör kalciumtitanoxidfamiljen. Vad den tyske mineralogen

https://www.naturvetenskap.lu.se/artikel/kemiforskare-har-tillverkat-sfarformade-lysdioder-tack-vare-enkel-angreaktion - 2026-05-25

Ny detaljkunskap om skadligt protein kan bli användbar i kampen mot Alzheimers

Med hjälp av röntgen- och neutronspridning har ett forskarlag i Lund lyckats kartlägga fibrillstrukturen hos proteinet beta-amyloid 42 som bidrar till Alzheimers sjukdom. Den nya kunskapen kan bli en viktig pusselbit i den framtida jakten på effektiva läkemedel. Vid Alzheimers sjukdom förtvinar nervcellerna i hjärnan vilket leder till minnesproblem och svårigheter att tolka intryck. Till en början

https://www.naturvetenskap.lu.se/artikel/ny-detaljkunskap-om-skadligt-protein-kan-bli-anvandbar-i-kampen-mot-alzheimers - 2026-05-25

Kemiforskare har tillverkat sfärformade lysdioder tack vare enkel ångreaktion

Forskare vid Lunds universitet har lyckats tillverka storskaliga och sfärformade LED-ytor vilket tidigare har varit en teknisk utmaning. Experimentet, som möjliggjordes av en enkel kemisk reaktion, kan bli avgörande för en betydligt billigare produktion av lysdioder. Perovskit är ett medelhårt mineral som upptäcktes i Uralbergen 1839 och tillhör kalciumtitanoxidfamiljen. Vad den tyske mineralogen

https://www.lu.se/artikel/kemiforskare-har-tillverkat-sfarformade-lysdioder-tack-vare-enkel-angreaktion - 2026-05-26

Ta hand om den som vårdar närstående

Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. De som vårdar närstående med demens eller depression har den högsta belastningen av anhörigvårdarna. Stödet från samhället är långt ifrån tillräckligt, menar Beth Dahlrup som nyligen disputerat vid Lunds universitet. - Anhöriga till personer med demens och anhöriga till personer med depression visar sig ha den högst

https://www.lu.se/artikel/ta-hand-om-den-som-vardar-narstaende - 2026-05-26