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Resolving the biological paradox of aneurysm formation in children with tuberous sclerosis complex

Aortic aneurysms are rare manifestations in children with tuberous sclerosis complex (TSC) with life threating implications. Although an association between TSC, aortic and other aneurysms has been recognized, mechanistic insights explaining the pathophysiology behind aneurysm development and genetic aberrations in TSC have so far been lacking. Here, we summarize existing knowledge on aneurysms in

Lever-, pankreas- och gallvägskirurgi

Leverkirurgiforskningen fokuserar på kliniska resultat och registerforskning, ffa leverkirurgi p.g.a. metastaser från tjocktarm-ändtarmscancer. Biomarkörforskning på vävnad i syfte att utveckla bättre diagnostik och framtida riktad behandling. Multimodala insatser utvärderas. Teknikutveckling av leverparenkymets kvalitet, inkl. genomblödning. Pankreascancerprojektet identifierar nya biomarkörer, Liver research focus on clinical results and registries, especially liver metastases from colorectal cancer. Biomarker research (cancer tissue) in order to improve diagnosis and targeted therapy. Multimodal treatment concepts are evaluated. Development of novel techniques evaluating the quality of liver parenchyma including tissue perfusion. Pancreatic cancer – identification of novel biomarkers,

Enheten för medicinens historia

Medicinen är ett kunskapsfält med humanistisk förankring. Vid Enheten för medicinens historia är målet att nå ökad förståelse för hur den medicinska vetenskapen tagit form över tid och fördjupad insikt kring det sociala sammanhang medicinen verkar i. Genom sin tillhörighet i ämnesområdet Medicinsk humaniora gränsar verksamheten till flera andra akademiska discipliner, såsom idé- och lärdomshistori

A Companion to Birgitta of Sweden : And Her Legacy in the Later Middle Ages

St. Birgitta of Sweden (d. 1373) is one of the most celebrated female visionaries and authors of the Middle Ages and a central figure in the history of late-medieval religion. An aristocratic widow, Birgitta left her native country in 1349 and settled in Rome, where she established herself as an outspoken critic of the Avignon Papacy and an advocate of spiritual and ecclesiastical reform. Birgitta

The sole trader's assets and liabilities - a tax law study on the importance of accounting to the demarcation of business activity

Sverige är ett utpräglat småföretagarland och mätt i antal bedrivs en klart övervägande del av företagen som enskild näringsverksamhet. Till skillnad från aktiebolag och andra juridiska personer, som hänför alla inkomster till inkomstslaget näringsverksamhet, ska inkomster eller utgifter för fysiska personer hänföras till endera av inkomstslagen näringsverksamhet, tjänst eller kapital. AvhandlingeSweden is a typical small-business country and, based on the numbers, a clear majority of the companies operate as sole traders. Unlike limited companies and other legal entities, which classify all income as business income, the income or expenditures of private persons are classified as either business, service or capital income. The main objective of this thesis is to systematically examine the

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the epistasis existing among oncogenesis-related genes in lung cancer development, we conducted pairwise genetic interaction analyses among 35,031 SNPs from 2027 oncogenesis-related g

Factors influencing concordance of pd-l1 expression between biopsies and cytological specimens in non-small cell lung cancer

PD-L1 expression assessed by immunohistochemical staining is used for the selection of immunotherapy in non-small cell lung cancer (NSCLC). Appropriate validation of PD-L1 expression in cytology specimens is important as cytology is often the only diagnostic material in NSCLC. In a previous study comprising two different cohorts of paired biopsies and cytological specimens, we found a fairly good

Survival on the Reregulated Swedish Pharmacy Market - The former monopoly Apoteket AB responds to competition

The purpose of the thesis is to study how a state owned monopoly company, with historical responsibilities towards society, is affected by competition and how it uses its resources to maintain a strong position on the competitive market. The case study has been conducted by using qualitative methods. Primary data has been collected through interviews with managers and former managers within Apotek

Guidance signs – for everyone? A study on the use and interpretation of the evacuation sign to route adapted for people with movement disabilities

The aim of this project is to evaluate the sign to evacuation routes that are adapted for people with a disability. The goal is to shed light on problem areas when the sign is used as well as in planning with evacuation signs. The sign was introduced to lead to evacuation points, evacuation elevators and routes to the outside adapted for people with disabilities. With help from experts, a literatu

Meet Victoria Heisler - Raoul Wallenberg Institutes new Librarian! - The Raoul Wallenberg Institute

Meet Victoria Heisler - Raoul Wallenberg Institutes new Librarian! - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analy

https://rwi.lu.se/news/meet-victoria-heisler-raoul-wallenberg-institutes-new-librarian/ - 2026-05-28

NanoLund Policy Research Visits

May 2022 Riktlinjer för stöd från NanoLund till internationella forskningsvistelser NanoLund önskar att stödja internationellt utbyte och inspirationsbesök i ledande internationella forskningsmiljöer. Pengar kan sökas närsomhelst under året från den exekutiva gruppen (ca 1 A4-sida). Resmål, resans längd och syfte med resan ska framgå. En budget för den förväntade totalkostnaden och sökt belopp är

https://www.nano.lu.se/sites/nano.lu.se/files/2022-05/NanoLund%20policy%20research%20visits.pdf - 2026-05-30

Dermatologi och venereologi, Lund

Allergiska och inflammatoriska hudsjukdomar. Medfödd immunitet. Sårläkning. Maligna melanom.Allergic and inflammatory skin diseases. Wound healing. Innate immunity. Malignant melanoma.

Autoimmunitet och njursjukdomar

I världen lider flera 100 miljoner människor av autoimmuna sjukdomar och de är ett folkhälsoproblem i paritet med cancer och hjärt/kärlsjukdomar. Vi har fokuserat vår forskning kring en grupp ovanliga men allvarliga autoimmuna sjukdomar, ANCA associerade vaskuliter. Sjukdomarna orsakar en akut inflammation i de små blodkärlen, vilket leder till en snabbt förlöpande glomerulonefrit och livshotande Autoimmune diseases affect several 100 million people world wide and is a tremendous public health problem comparable with heart disease and cancer. We have focused our research to a group of severe autoimmune diseases, called ANCA (anti-neutrophil cytoplasmic antibody) associated systemic vasculitis. The diseases present with acute inflammation in the small vessels and cause rapidly progressive r