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Trots de senaste årtiondenas betydande framsteg inom cancerforskningen, vilket bland annat avspeglas i ett ständigt ökande utbud av nya läkemedel, har cancerdiagnostiken, som bedrivs av patologer, inte utvecklats i samma takt. För att uppnå visionen om individualiserad cancerbehandling måste därför den kliniska patologin utveckla bättre verktyg för att kunna identifiera biologiska särdrag, s.k. biThe pathologist’s role is to deliver accurate diagnosis of disease, so as to enable optimal treatment strategies for individual patients. In the wake of the ‘omics revolution, with an increasing availability and impact of a wide range of molecular technologies, clinical pathology is currently undergoing a paradigm shift. However, despite the clear value of these technologies in further refining th

BACKGROUND: The advent of PD-1/PD-L1 inhibitors has revolutionized lung cancer treatment, necessitating accurate PD-L1 immunohistochemical (IHC) assessment. While standardized for formalin-fixed paraffin-embedded (FFPE) histological samples, PD-L1 testing on cytology remains challenging. This review aims to address the complexities of PD-L1 IHC in cytology, focusing on validation guidelines, quali

When a course is designed, it is common to do it for a typical group of students, considered to represent “the majority”, the “norm” or the “average”. The concept of “edges” challenges this view: given the multiple dimensions that teaching and learning encompass, there will always be students who do not belong to a norm and will end up on an edge if they are not included in the course design. In t

https://www.genus.lu.se/welcome-gender-studies-gender-and-nation-europe-75-hp - 2026-05-27

Through a comparative analysis of works by street artists Faile and Banksy, from both the street and the gallery, I make the point that the field of modern street art is not as homogenous as the media and the established art world often portray it. By differentiating between sub- and counter-cultural agents, I point out the span of social and ideological backgrounds within the street art culture a

The Consiglio Lab investigates how biological sex impacts human immunity using systems immunology approaches. Generally, females mount more robust immune responses than males, resulting in lower severity of infections, decreased frequency of cancer, but increased prevalence of autoimmunity. Yet, we do not fully understand the precise mechanisms that underlie such sex discrepancies. Our lab combi

The current Lambda Cold Dark Matter cosmology predicts galaxy growth by hierarchical merging, leading to galaxy substructure like tidal streams and dark matter subhalos devoid of stars. The goal of this thesis is to investigate whether tidal stream-subhalo interactions can leave observable gaps in the streams, and at which rate this might happen in a galaxy like the Milky Way. The stream-subhalo i

Urban establishment from scratch based on a smart city vision has been mainstreamed as a strategy to achieve urban sustainability goals. However, the smart city model itself has been criticized because of how the techno-centric solutions it uses could potentially lead to economic and social inequality. Urban Political Ecology (UPE) focuses on how the urban production process involve commodificatio

We investigate a class of random graph ensembles based on the Feynman graphs of multidimensional integrals, representing statistical-mechanical partition functions. We show that the resulting ensembles of random graphs strongly resemble those defined in random graphs with hidden color, generalizing the known relation of the Feynman graphs of simple one-dimensional integrals to random graphs with a