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This thesis focuses on the case of education and habilitation services in Cienfuegos, Havana, and Pinar del Rio to describe the well-being of persons with intellectual disability. The welfare of the target group is assessed through an ethnographic study of how actors from the societal sectors policy/service/household perceive that the well-being of individuals with intellectual disability is and c
Problem – Despite supply chain flexibility is recognized as a competitive advantage in today’s business, and supply chain information system is one of the most critical tool to facilitate flexibility. There is no consensus or comprehensive description on how information system tailor with and work on supply chain flexibility to achieve better dynamic capability. Most of literatures mainly focus on
Suzanne Collins’ trilogy The Hunger Games is, thus far, one of the 21st century’s most well known young adult series, and Collins has been praised for challenging things such as gender stereotypes and genre limitations. It has been labelled as a contemporary young adult dystopian novel, and has a strong female protagonist. I explored the idea of The Hunger Games Trilogy being both a dystopian nove
Användningen av ytaktiva ämnen i industrin sträcker sig över många olika användningsområden med en mängd tillämpningar. Detta möjliggörs på grund utav den karakteristiska tvådelade amfifila strukturen, vilket leder till mycket specifika och unika egenskaper. Ett tillämpningsområde är exempelvis inom läkemedelsformulering där de interagerar med biomolekyler, såsom proteiner. Att addera ytaktiva ämnThe use of surfactants in the industry covers a wide field with a lot of different applications. Due to the characteristic structure of surfactants they are able to interact with biomolecules such as proteins, where interactions may result in either devastating or lifesaving effects. Devastating in the sense of those surfactants may alter the protein structure and dynamics, which in turn will aff
To address the problems that had sprung from the detail management of the welfare sector, a result of control in the vein of New Public Management (NPM), the Swedish government commissioned the Trust Delegation (Tillitsdelegationen) to develop a trust-based steering and launched the Trust Reform (Tillitsreformen). As this new reform seeks to remedy the failures of the previous system, this thesis
Isolated attosecond pulses are often generated via sub-optical-cycle polarization gating. This technique, based on the precise control of the time-dependent polarization of the infrared driver pulse, enables strong temporal confinement of the extreme ultraviolet (XUV) emission from high-order harmonic generation (HHG) in gases. In this work, we study the influence of pulse propagation between the
Venetoclax-obinutuzumab (Ven-Obi) is a standard first-line therapy for chronic lymphocytic leukemia (CLL). The impact of age, fitness, and dose reductions remains unclear. We analyzed patients treated with Ven-Obi in the CLL13 and CLL14 trials, excluding patients with TP53 aberrations. Fitness was assessed using the cumulative illness rating scale (CIRS, >6) and creatinine clearance (≤70 mL
Therapeutic proteins are essential in modern medicine but are often susceptible to chemical degradation during production, transportation, and storage, which can compromise functionality and even lead to immunogenicity in patients. This study investigates how the structure of the affibody GA-Z affects its chemical stability and how glycerol stabilizes the protein against deamidation and isomerizat
Rwanda’s Nyabarongo catchment frequently experiences floods, highlighting the need for effective flood susceptibility analysis and management. This study mapped flood susceptibility in the catchment using the random forest (RF), support vector machine (SVM), eXtreme Gradient Boosting (XGBoost), SHapley Additive exPlanations (SHAP) models, as well as various conditioning factors including elevation
Light metal borohydrides are considered as promising materials for solid state hydrogen storage. Because of the high hydrogen content of 11.5 wt % and the rather low dehydrogenation enthalpy of 32 kJ mol(-1)H(2), Ca(BH4)(2) is considered to be one of the most interesting compounds in this class of materials. In the present work, the effect of selected TM-fluoride (TM = transition metal) additives
Inflammatory responses to acute stimuli are proposed to regulate sleep, but the relationship between chronic inflammation and habitual sleep duration is elusive. Here, we study this relation using genetically predicted level of chronic inflammation, indexed by CRP and IL6 signaling, and self-reported sleep duration. By Mendelian randomization analysis, we show that elevated CRP level within <10 mg
Darknet framställs ofta som en digital värld präglad av avvikelse och kriminalitet – en plats där ”allt är tillåtet” och som därför anses kräva övervakning och kontroll. Trots detta är kryptoforum fortfarande relativt understuderade. Med utgångspunkt i tre års etnografiskt fältarbete ger denna avhandling nya insikter i de interna dynamikerna i en till stor del dold onlinegemenskap. Genom att kombiThe Darknet is often portrayed as an online realm marked by deviance and criminality – a space where “anything goes” and therefore requires policing. Yet its cryptoforums remain comparatively understudied. Drawing on three years of ethnographic fieldwork, this dissertation provides new insights into the internal dynamics of a largely hidden online community. Combining digital observations with 19
Breaking promises might be easier if one faces unexpectedly high costs for keeping them. Inspired by the ‘pledge and review’ mechanisms of the Paris Agreement, we investigate the role of cost uncertainty for both initial non-binding pledges and the subsequent voluntary provision of public goods. Without a pledge review process, we find that cost uncertainty not only leads to rather conservative pl
Among thermal improvements of external walls in heritage buildings, interior insulation of external walls might be the only option. However, interior insulation is associated with several risks of damage due to the diminishment of the hygrothermal performance of the existing wall. This project aims to assess the impact of available solutions for interior insulation through field measurements and h
Scholars and policy makers have intensely debated institutional reforms of the United Nations (UN) since its creation. Yet, relatively little attention has been given to institutional design preferences among the public in UN member states. This study examines two questions: Which possible rules concerning UN authority and representation do citizens prefer? Which personal and country characteristi
ten-a is one of the two Drosophila genes whose products belong to the Ten M protein family. TheTen-a protein is a type II transmembrane protein. This protein was found to be mainly expressed in the CNSof the embryo and in the compound eye of the pupa. No report about the function of ten-a has beenpublished to date. Here, we showed, in a preliminary report, that ten-a has a function in the developm
Age-related physiological impairment increases susceptibility to syncope. We tested the hypotheses that cerebral oxygenation during orthostatic provocation, as well as the level at which syncope occurs, differs according to age. Non-invasive hemodynamic monitoring and cerebral oximetry were applied during a head-up tilt test in 139 patients with vasovagal syncope (mean (SD) 45, (17) years, 60%-fem
During the period 1920--30, there was a certain interest in north-westem Argentina's archaeology and ethnography at Etnografiska Museet. This interest had its roots in the so called "Expedition Chaco-Cordillera" led by Erland Nordenskiöld in 1901-1902. In 1932, Alfred Metraux visited Etnografiska Museet and inspired, among others, Stig Ryden, one of Erland Nordenskiöld's students. In the same ye
