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Exercise-induced bronchoconstriction (EIB) can be prevented by a single dose of montelukast (MLK). The effect is variable, similar to the variable responsiveness observed after daily treatment with MLK. We hypothesized that the effect of a single MLK-dose (5 or 10 mg) on EIB could predict the clinical effectiveness of longer term once daily treatment.

The Ile148Met (rs738409, G-allele) in the patatin-like phospholipase domain-containing protein 3 gene (PNPLA3) associates with liver fat content and may lead to loss-of-function (hydrolysis) or gain-of-function (CoA-dependent lysophosphatidic acid acyltransferase) defects. PNPLA3 is up-regulated by dietary carbohydrates, and interactions between rs738409 and carbohydrates, and sugar and ω6:ω3-poly

AIM/HYPOTHESIS: Individuals at risk of developing type 2 diabetes show a progressive decline in insulin secretion and increased insulin resistance over time. However, inability of the beta cells to compensate for the increased insulin resistance represents a key defect leading to overt type 2 diabetes. The aims of the present study were to replicate the association between genetic variants of the

Quality is an aspect of high importance in software development projects. The software organizations have to ensure that the quality of their developed products is what the customers expect. Thus, the organizations have to verify that the product is functioning as expected and validate that the product is what the customers expect. Empirical studies have shown that in many software development pro

Abstract Objective. To increase the accuracy of estimated GFR (eGFR) from creatinine overall and at measured GFR ≥90 mL/min per 1.73 m(2) by revising the Lund-Malmö (LM) equations, to elaborate on more complex forms to improve the LM and CKD-EPI equations further, and to assess benefits of adding lean body mass (LBM). Material and methods. Swedish Caucasians (n = 850, 376 women; median 60, range 1

Approximately 5-10% of prostate cancer cases are caused by dominantly inherited susceptibility to the disease. Although advances have been made in research concerning the genetic mechanisms of hereditary prostate cancer, little is known about the psychological consequences for men at high risk of developing the disease. The aims of the present study were to examine risk perception, interest in gen

A growing political interest in the development of biorefineries is being shaped by climate change and a need to develop economically viable substitutes (i.e., fuels, products and chemicals) to those produced in traditional oil refineries. The pulp and paper industry in Sweden has been stagnating and it is therefore potentially promising to integrate biorefining into its activities as one way of d

This text is an attempt to approach fundamental layers in the formation ofmusical meaning in learning processes where musicians work with musicfrom cultures other than their own. The point of departure is my personalexperience as a musician from two distinct perspectives:• my double roles as a teacher of the zither đàn tranh in the VietnamNational Academy of Music as well as in the Malmö Academy o

We use the cooling method and the lattice approximation to study the form and properties of the minimum action configurations for the SU(2) Yang-Mills theory on a space-time torous with twist k=m=(1, 1, 1).

This paper continues the discussion in a previous paper [Saeidpour and Wadsö doi:10.1016/j.cemconres.2016.02.003] where a clear effect of sorption hysteresis was seen in moisture diffusion coefficients for cement-based materials. Coefficients with vapor content as potential (Dv) had different values depending on whether the sample was in absorption or in desorption. In this paper we recalculate th

What does it mean to feel suspense? What kinds of situations give rise to the emotion? What is the connection between suspense and narrativity? And how is it that we can feel suspense upon repeat encounters with the same narrative? These questions are at the center of the first part of this study, where I develop and defend the ‘imminence theory of suspense’. Central to this theory is the claim th

This paper discusses some of the main issues of efficient analysis of electrically very large endfire arrays, and further proposes approaches for developing flexible simulation tools for this particular purpose. Some initial results supporting the endfire array design issue are presented, as well as some preliminary examples of implemented compression- and acceleration methods.

Objectives In rheumatoid arthritis (RA), seropositive and seronegative disease may be two entities with different underlying pathophysiological mechanisms, long-term outcomes and disease presentations. However, the effect of the conjoint presence of multiple autoantibodies, as proxy for a more pronounced humoral autoimmune response, on clinical phenotype remains unclear. Therefore, this study inve