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A novel electrode array was developed based on the XNA on Gold(TM) microarray platform. The platform combines self-assembling monolayers, thick film patterning and streptavidin based immobilization to provide a robust, versatile platform capable of analysing virtually any biomolecule including nucleic acids, proteins, carbohydrates and lipids. Electrochemical analysis of the self-assembling monola
B vitamins and polymorphisms in genes coding for enzymes involved in one-carbon metabolism may affect DNA synthesis and methylation and thereby be implicated in carcinogenesis. Previous data on vitamins B2 and B6 and genetic polymorphisms other than those involving MTHFR as risk factors for gastric cancer (GC) are sparse and inconsistent. In this case-control study nested within the European Prosp
Background: To investigate hand bone loss (HBL) measured by digital X-ray radiogrammetry (DXR) in patients with early rheumatoid arthritis (RA) receiving different treatment regimens, and to evaluate if DXR change rates during the first 12 months correlate with radiological damage after 24 months. Methods: From the total SWEFOT trial population, 159 patients had hand radiographs correctly timed an
The article discusses the philosophical debate between Karl Löwith and Hans Blumenberg. Contrary to figures such as Landauer and Buber – but also to a number of other figures discussed in this volume – these two thinkers were united in their hesitance about the purportedly constructive impact of the biblical theological legacy on modern political thought. Significant to both philosophers, in spite
Receding horizon control is a well established approach for control of systems with constraints and nonlinearities. Optimization over an infinite time-horizon, which is often computationally intractable, is therein replaced by a sequence of finite horizon problems. This paper provides a method to quantify the performance degradation that comes with this approximation. Results are provided for prob
Today there is ample evidence that the Cognitive Interview (CI) enhances witnesses' memory. However, less is known about how the CI affects eyewitnesses' confidence. To address this shortcoming we conducted a study analyzing how realism in confidence was affected by the CI. All participants (n = 79) were first shown a filmed kidnapping. After 2 weeks we interviewed one-third of the participants ac
The expanding capacity and the stabilizing function of an alpha-crystalline emulsifier on the bubble surfaces during and after expansion of a sugar foam were examined by volume measurements, confocal laser scanning microscopy (CLSM), freeze-etching and transmission electron microscopy (TEM) and oscillatory theological measurements. 0.2-10% (w/w) emulsifier, either a polyglycerol ester mixed with m
Objective. The redistributive effect of the welfare state is traditionally measured by comparing the gross and net distribution of annual income among adults. This standard approach does not account for the fact that a large share of the taxes paid by adults are paid back to the very same individuals later in life. The objective of this article is to examine the factors that determine the differen
In this note we give a complete classification of those holomorphic maps phgr:UrarrCopf n defined on open and connected subsets of Copf m which are harmonic morphisms.
Researchers examining self-esteem functioning typically consider self-esteem either an affective or competence related trait. However, to capture more precisely the role of self-esteem in behavior we need to view self-esteem both as something people hold and as something they strive for, and determine the relation between these aspects. In the present study the consequences of the dynamic interpla
For dynamical systems defined by a covering map of a compact Hausdorff space and the corresponding transfer operator, the associated crossed product C (*)-algebras C(X)a < S (alpha,a"')a"center dot introduced by Exel and Vershik are considered. An important property for homeomorphism dynamical systems is topological freeness. It can be extended in a natural way to in general non-invertible dynamic
Recently updated hydrogen combustion mechanism was combined with ozone decomposition reactions and extended by reactions of excited species: O(D-1), OH((2)Sigma(+)), and O-2(a(1)Delta g). The reliability and the accuracy of the rate constants pertinent to these excited species were evaluated. Many reactions proposed in the literature and implemented in other kinetic schemes were found irrelevant o
Introduction: Elderly patients often use many drugs, increasing the risk for drug-related problems. Aim: To optimise drug therapy in the elderly by identifying, resolving and preventing drug-related problems. Methods: (Paper I) Medication reviews were conducted on nursing home patients’ with epilepsy or Parkinson’s disease by a multi-speciality team, whom identified drug-related problems and whe
Paracellular permeability is determined by the complex structures of junctions that are located between the epithelial cells. Already in 1996, it was shown that the human probiotic strain Lactobacillus plantarum 299v and the rat-originating strain Lactobacillus reuteri R2LC could reduce this permeability in a methotrexate-induced colitis model in the rat. Subsequently, many animal models and cell
Purpose Hip dislocation after arthroplasty for femoral neck fractures (FNF) remains a serious complication. The aim of our study was to investigate FNF patients treated with THA, with a special focus of comparing the effect of surgical approach and femoral head size on the risk of revision for dislocation. Methods Data were derived from the Lithuanian Arthroplasty Register, and we calculated the c
Background: In 2007 the World Cancer Research Fund (WCRF) and the American Institute of Cancer Research (AICR) issued 8 recommendations (plus 2 special recommendations) on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. Objective: We aimed to investigate whether concordance with the WCRF/AICR recommendati
The H(2) optimization problem with preview and asymptotic behavior constraints is considered in a general two-sided model matching setting. The solution is obtained in terms of two constrained Sylvester equations, associated with asymptotic behavior, and stabilizing solutions of two algebraic Riccati equations. The Riccati equations do not depend on the preview length, yet are affected by asymptot
Land-use change is a major driver of the global loss of biodiversity, but it is unclear to what extent this also results in a loss of ecological traits. Therefore, a better understanding of how land-use change affects ecological traits is crucial for efforts to sustain functional diversity. To this end we tested whether higher species richness or taxonomic distinctness generally leads to increased
