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Different radiological methods play an important role in the work-up of patients complaining of spine pain. Depending on the symptoms and the suspected underlying etiology different methods are selected. In the following presentation we briefly present the different radiological and magnetic resonance tomography methods that are at hand, give some guidance in which method to use, and present the t
The molecular mechanics/generalized Born surface area (MM/GBSA) method has been investigated with the aim of achieving a statistical precision of 1 kJ/mol for the results. We studied the binding of seven biotin analogues to avidin, taking advantage of the fact that the protein is a tetramer with four independent binding sites, which should give the same estimated binding affinities. We show that i
In this chapter, we first elaborate on the discussion of the nature of CKEs that has taken place in the previous chapters in the book. Secondly, we summarise the main lessons we have learnt about CKEs from the studies reported in this book. Thirdly, we identify and analyse what circumstances and conditions promote creativity in organisations and which ones hinder it. We also identify some of the m
Scientific and clinical communities produce ever increasing amounts of data and details about health and disease. Our ability to understand and utilize this information is limited because of imprecise language and lack of well-defined concepts. This problem involves also the principal concepts of health, disease, and pathogenicity. Here, a systematic model is presented for pathogenicity, as well a
In this paper we summarize the properties of nu (dyn) and discuss briefly how the results can be interpreted in terms of a simple pair-production model. The ideas are then illustrated in detail with a PYTHIA simulation study of forward-backward correlations in pp collisions.
Within the realm of furniture is the copy a controversial subject matter and is often discussed in terms of “real or fake”, “copy or original”. Walter Benjamin was probably the first theorist to pay attention to the power of the copy, in terms of changing our social and cultural attitudes towards the nature of representation with his Das Kunstwerk im Zeitalter seiner technischen Reproduzierbarkeit
