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The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes

Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. The aim of this thesis was to analyze DNA methyla

Industrialised House-Building - Conceptual orientation and strategic perspectives

Industrialised house-building has received increasing attention within both the construction industry and the scientific community during the last 15 years. However, industrialisation of house-building is not a new phenomenon, it has been applied to various extents throughout modern history, although the understanding and descriptions of it have developed over time. Scientifically, industrialised