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The influence of external precipitating factors and the presence of peripheral neuropathy on the development and outcome of foot ulcers were evaluated in 314 consecutive diabetic patients. All patients were treated by the same foot care team. Each patient was represented by one ulcer, and primary healing was defined as intact skin for at least six months. External precipitating factors were identi

BACKGROUND: Because hemodilution decreases the oxygen-carrying capacity of blood, it was hypothesized that severe hemodilution would decrease the tolerance to alveolar hypoxia. METHODS: Hemodynamics, oxygen transport, and blood lactate concentrations were compared in ten pigs with normal hematocrit (33 +/- 4%), and ten hemodiluted pigs (hematocrit 11 +/- 1%; mean +/- SD) anesthetized with ketamine

We have analyzed the development of aortic and coronary atherosclerosis over 40 years in native and non-native males of Yakutsk by comparing the data obtained in 1963-1965, 1985-1987 and 2001-2003. The research was carried out in compliance with the WHO program for the atherosclerosis epidemiology studies using autopsy material. Subjects (361 natives and 692 non-natives) included in the research d

A prospective randomized double-blind trial was performed comparing conventional low-dose heparin with a low molecular weight heparin fragment for thromboprophylaxis in elective general abdominal surgical patients. The first dose of the heparin fragment was given the evening before surgery, and further doses were given thereafter every evening. There were 1002 analysable patients, 826 having recei

Recently it has been shown that there is impaired cerebral endothelial function in many chronic neurodegenerative disorders including Alzheimer's and Huntington's disease. Such problems have also been reported in Parkinson's disease, in which α-synuclein aggregation is the pathological hallmark. However, little is known about the relationship between misfolded α-synuclein and endothelial function.

Objective: To identify possible suicide risk factors in a clinical sample and suicide risk in a general population, with primary focus on mental disorders, signs, symptoms and comorbidity. Methods: In the first two studies, subjects who had been admitted to a specialised psychiatric ward after a suicide attempt were investigated. Fifteen suicide completers were compared to matched survivors in te

It is a common experience among children to witness domestic violence, but how much does it affect the child later on in life? The purpose of this paper is to present what happens to the child mentally and physically when domestic violence against women results in the death of a mother and the imprisonment of a father. The paper also presents ways to minimize the impact the event has on the child.

Abstract Toxic cyanobacterial blooms can form in both freshwater and marine environments, which could threaten the health of human beings and animals. The genera that are known for causing the scums in freshwater are Anabaena, Microcystis, Cylindrospermopsis and Planktothrix. In order to control lake water quality and minimize the potential health risk associated with the cyanobacterial blooms, th

During the last two decades, survival rates after cardiac arrest have increased while the fraction of patients surviving with a severe neurological disability or vegetative state has decreased in many countries. While improved survival is due to improvements in the whole chain of survival, improved methods for prognostication of neurological outcome may be of major importance for the lower disabil

Anticoagulant treatment of acute pulmonary embolism (PE) has traditionally been hospital-based. The lesser need for monitoring with the increasingly used direct acting oral anticoagulants (DOAC) in comparison to warfarin potentially facilitates outpatient treatment of PE with these drugs. This study aimed to evaluate efficacy and safety of outpatient treatment of PE with DOAC. We extracted data fr

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA (COMPREHENSIVE SUMMARY IN SWEDISH) Bakgrund Kritisk extremitetsischemi (KI), d.v.'s. cirkulationsstörning på grund av åderförkalkning i nedre extremiteterna's tillförande blodkärl med vilovärk och/eller sårbildning, har dålig progno's. Förekomsten av KI i Sverige har tidigare varit bristfälligt känd. Samtliga patienter meIn Conclusion Paper I. In patients undergoing aorto-iliac angiography, no effects of the procedure were seen upon inflammatory mediators. On the other hand, angiography influenced markers of platelet activation in these patients. Paper II. The incidence of CLI in southern Sweden is 38/100 000 subjects/year. Both medical risk factors for atherosclerosis and concomitant cardiovascular disease