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One of the most effective methods for obtaining bulk ultrafine-grained materials is severe plastic deformation that is typically done using equal channel angular pressing. In this work we describe and analyze a new method for obtaining severe plastic deformations proposed by the first author. The method is based on direct extrusion and was called "twist extrusion" The main idea of the method is to

The aim of this study was to study long-term outcome of physical health and self-injurious behaviour (SIB) in anorexia nervosa (AN). Fifty-one adolescent-onset AN cases, originally recruited after community screening, and 51 matched controls (COMP) were interviewed regarding somatic problems and SIB and physically examined 18 years after AN onset, at mean age 32 years. Six individuals had an eatin

There is a growing evidence that neuropeptides may be involved in the pathophysiology of suicidal behavior. A critical review of the literature was conducted to investigate the association between neuropeptides and suicidal behavior. Only articles from peer-reviewed journals were selected for the inclusion in the present review. Twenty-six articles were assessed for eligibility but only 22 studies

Mixed feelings: fear and consolation now and then (from the 17th to the 21st century). In Early Modern Swedish society a great amount of ideas, words and images were available to explain the earthly suffering. In the Lutheran practice of preaching, consolation, besides instruction and admonition, played an important role. Today, our life is not as hard as our ancestors’ was. This has enabled us to

The objective of this study was the investigation of the maximal potential donor pool and causes of non-realized organ donation. On-site retrospective medical-record review was performed for all cases of patient death (n=1608) occurring in 1999 at 34 (83% of all) intensive care units (ICUs) in the region of the transplant center in Prague, Czech Republic. Two hundred and eighty-eight (18%) patient

Five Swedish patients with chronic hepatitis C were prospectively followed until hepatocellular carcinoma (HCC) developed. Hepatitis C virus (HCV) antibodies were analysed by a second generation anti-HCV ELISA and a recombinant immunoblot assay (RIBA-2) and viraemia by detection of serum HCV RNA by polymerase chain reaction. Four patients had post transfusion hepatitis and in one patient the sourc

C4b-binding protein (C4BP) is the main fluid-phase inhibitor of the classical complement pathway. It serves as cofactor in factor I-mediated cleavage of C4b and C3b and it accelerates the decay of complement convertases. The main role of C4BP is to prevent overt complement-mediated inflammation both in solution and on self-molecules recognised by C1q, such as amyloid. Furthermore, C4BP is frequent

Aim: To assess the quality of life in frail older persons (65+ years) living in nursing homes and to examine differences between quality of life perceptions among different gender and age groups. Design: Cross-sectional. Methods: Data were collected during 2015-2017 based on two questionnaires (WHOQOL-OLD and WHOQOL-BREF). Seventy-eight older persons living in nursing homes in southern Sweden answ

We present a unifying theory to explain cancer recurrence, therapeutic resistance, and lethality. The basis of this theory is the formation of simultaneously polyploid and aneuploid cancer cells, polyaneuploid cancer cells (PACCs), that avoid the toxic effects of systemic therapy by entering a state of cell cycle arrest. The theory is independent of which of the classically associated oncogenic mu

This paper presents a hysteretic (sliding mode) control IC for a buck DC/DC converter for use as an envelope tracking power supply to increase the efficiency of an RF power amplifier. The IC integrates a high-bandwidth error amplifier, a comparator with hysteresis, and a high-side driver for an external N-channel power MOSFET. The total control loop delay using the implemented IC is 35ns, this is

Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after

The recent economic crisis caught many by surprise. Yet some firms were better prepared to weather the downturn than others. Using a unique micro dataset of shareholding companies from emerging countries in Eastern and Southern Europe derived from the World Bank's Enterprise Surveys, we econometrically test the hypothesis that pre-crisis innovation affected their survival odds and performance ther

PurposeIn a retrospective cohort study of intensive care unit (ICU) admitted adult patients with suspected or confirmed infection, associations between combination versus mono empirical antibiotic therapy and clinical cure at day 7 as well as mortality at day 7 and 28, were investigated.Materials and methodsPatients from the DIANA study were grouped and analysed by combination versus mono antibiot

Since the type fossil was found, 153 years ago, the Neanderthal man has fascinated researchers and laymen alike. The Neanderthals lived in Eurasia for maybe 200,000 years but disappeared around the time when modern humans moved into Europe around 35,000 BP. New studes of bones and artifacts, and intriguing results of new DNA-technology, indicate that Homo neanderthalensis was a separate species- b