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Background: The metabolism of amyloid precursor protein (APP) and beta-amyloid (A beta) is widely studied in Alzheimer's disease, where A beta deposition and plaque development are essential components of the pathogenesis. However, the physiological role of amyloid in the adult nervous system remains largely unknown. We have previously found altered cerebral amyloid metabolism in other neuroinflam
The aim of this thesis, The Historical Novel and Historical Consciousness in ten- to twelve-year-olds - Maj Bylocks Drakskeppstrilogi in Theory and Practice, is to illustrate the possibilities for pupils of the ages between ten to twelve to develop their historical consciousness by participating in classroom work making use of fiction as a central source of knowledge.
In the first part
The purpose of this study was to identify if and how the personal perspectives and views of social workers active within local social services departments in Sweden might affect how they carry out the transfer of children’s custody from biological to foster parents. The general discourse in child welfare in Sweden gives predominance to a family preservation perspective in which foster care placeme
Advertisements use cultural symbols and myths that exist in society. When women are represented at work in advertisements it often illustrates their subordinate position to men. This illustrates the gender system: how men as a group have more power than women as a group. The concentration here is on TV-advertisement's representation of women in connection to work, power, and objectification. M
Agile methods have the recent years gained ground within the software industry by being lean and flexible, and one of the companies having adopted agile methods is the fast‐growing Swedish developer of mobile applications Tactel AB. The company was interested in enhanced knowledge within the agile area, specifically about Scrum, and with one of its development teams – Mobical – in focus, Tactel wa
Titel: Marknadens leoparder - om first mover advantage och betydelsen av att vara först Seminariedatum: 30 maj 2012 Kurs: FEKN90, Examensarbete i företagsekonomi på magisternivå, 30 högskolepoäng. Författare: Victor Bengtsson & Mikael Falk Handledare: Matts Kärreman Fem nyckelord: First Mover Advantage, Red Queen, Konkurrensfördelar, Leoparder, Marknadsledare. Syfte: Syftet med studien Title: The Leopards of The Market - on First Mover Advantage and The Importance of Being First Seminar date: May 30th, 2012 Course: Master thesis in business administration, 30 University Credit Points (30 ECTS) Authors: Victor Bengtsson & Mikael Falk Advisor/s: Matts Kärreman Five key words: First Mover Advantage, Red Queen, Competitive Advantages, Leopards, Market Leadership. Purpose:
Metrical versions of the Passion form a significant part of the substantial body of devotional literature written in Europe during the 17th and 18th centuries. The aim underlying them was twofold: to meet the demand for works which could be used for purposes of educadon, edification, and private worship but also to show that the vanacul-ars could be used to produce distinguished works written in a
Experiences early in life strongly shape values, attitudes and behaviour and serve as reference points ever after. Those who grew up in a society where resources are scarce may behave differently in an affluent society than those who got used to affluence even as children. This hypothesis was tested among 600 households in a major Swedish city who responded to questions about energy related behavi
An experimental study of the Homogeneous Charge Compression Ignition (HCCI) combustion process has been conducted by using chemiluminescence imaging. The major intent was to characterize the flame structure and its transient behavior. To achieve this, time resolved images of the naturally emitted light were taken. Emitted light was studied by recording its spectral content and applying different f
Objective: To describe the incidence of incorrect computerized ECG interpretations of atrial fibrillation or atrial flutter in a Swedish primary care population, the rate of correction of computer misinterpretations, and the consequences of misdiagnosis. Design: Retrospective expert re-analysis of ECGs with a computer-suggested diagnosis of atrial fibrillation or atrial flutter. Setting: Primary h
Nils Wohlin and the question of inheritance patternsIt has long been assumed that inheritance patterns varied strongly betweendifferent regions. In the early 20th century statistician Nils Wohlin made afamous account of Swedish inheritance patterns, claiming significant differences between Swedish provinces, especially between eastern and western Sweden. Newer studies of inheritance patterns have
IntroductionNational and regional carbapenemase-producing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment recommendations.AimThis study aimed to describe CPE and their epidemiology in Norway from 2015 to 2021.MethodsA nationwide, population-based observational study
Importance: The effect of a physical property of irrigation fluid (at body vs room temperature) on recurrence rate in the evacuation of chronic subdural hematoma (cSDH) needs further study. Objective: To explore whether irrigation fluid temperature has an influence on cSDH recurrence. Design, Setting, and Participants: This was a multicenter randomized clinical trial performed between March 16, 20
Survival has improved among patients with diffuse large B-cell lymphoma (DLBCL) with the addition of anti-CD20 antibody therapy. We aimed to quantify trends and remaining loss in expectation of life (LEL) due to DLBCL at a national population-based level. Patients diagnosed with DLBCL 2000-2013 (N = 7114) were identified through the Swedish Lymphoma Registry and classified according to the age-adj
Multi‐compartment T2 mapping has gained particular relevance for the study of myelin water in the brain. As a facilitator of rapid saltatory axonal signal transmission, myelin is a cornerstone indicator of white matter development and function. Regularized non‐negative least squares fitting of multi‐echo T2 data has been widely employed for the computation of the myelin water fraction (MWF), and t
OBJECTIVES: Chronic lung allograft dysfunction including Bronchiolitis obliterans syndrome (BOS) is common after lung transplantation. Histologically, BOS is recognized as fibrotic lesions with accumulated extracellular matrix (ECM) in small airways. Lung fibroblasts are major producers of ECM and vascular endothelial growth factor (VEGF). In this study we hypothesize that VEGF is involved in BOS
Objectives: To evaluate the potential of artificial intelligence (AI) to identify normal mammograms in a screening population. Methods: In this retrospective study, 9581 double-read mammography screening exams including 68 screen-detected cancers and 187 false positives, a subcohort of the prospective population-based Malmö Breast Tomosynthesis Screening Trial, were analysed with a deep learning–b
Objectives: Study the effect of introducing a template for radiological reporting of non-enhanced computed tomography (NECT) in the primary care diagnostic work up of cognitive impairment using visual rating scales (VRS). Methods: Radiology reports were assessed regarding compliance with a contextual report template and the reporting of the parameters medial temporal lobe atrophy (MTA), white matt
Background: Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. Mast cell responses are important in asthma as they, upon activation, release mediators inducing bronchoconstriction, inflammatory cell recruitment, and often remodelling of the airways. As guinea pigs exhibit anatomical, physiological, and pharmacological features resembling hu
Rationale: Mechanisms underlying vasomotor abnormalities and increased peripheral resistance exacerbating heart failure (HF) are poorly understood. Objective: To explore the role and molecular basis of myogenic responses in HF. Methods and Results: 10 weeks old C57Bl6 mice underwent experimental myocardial infarction (MI) or sham surgery. At 1 to 12 weeks postoperative, mice underwent hemodynamic
