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PURPOSE: When central nervous system axons are injured, regeneration is partly inhibited by myelin-associated inhibitors (MAIs). Following traumatic brain injury (TBI) in the rat, pharmacological neutralisation of the MAIs Nogo-A and myelin-associated glycoprotein (MAG) resulted in improved functional outcome. In contrast, genetic or pharmacological neutralization of the MAI receptors Nogo-66 rece

Background: From middle childhood onwards, substantial evidence points to phenotypic differentiation between anxiety diagnostic categories such as generalised anxiety, separation anxiety, specific phobia, and obsessive-compulsive disorders. However, little is known about the genetics of these categories and especially about the phenotypic and genetic structure of related behaviours in pre-school c

BACKGROUND: Global haemostatic tests are often abnormal in critically ill patients, secondary to activation or consumption of coagulation factors or inhibitors. Methods for analysing plasma levels of these factors are, however, not widely available, and the predictive value of global tests is not known. We examined the clinical applicability to predict the outcome of the global haemostatic tests u

The process stability of water-in-oil-in-water (W/O/W) double emulsions stabilized with food-grade OSA modified quinoa starch granules was investigated. The effect of oils with differing melting points, as well as the effect of in situ partial gelatinization of the granules, on stability of emulsions was also investigated. The physical stability and release of a tracer (carmine) from the internal

Aims: To evaluate the effects of adding glucagon-like peptide-1 (GLP-1) analogue therapy to insulin on glycated hemoglobin (HbA1c), weight, insulin dosage, treatment satisfaction, and risk of hypoglycaemia. Methods: Type 2 diabetes patients with insulin therapy receiving a GLP-1 analogue at 4 Swedish centers were studied. Hypoglycemia was evaluated using glucometers and patient self-report. The Di

Objectives: To explore the views of experts about the development and validation of a robotic surgery training curriculum, and how this should be implemented. Materials and methods: An international expert panel was invited to a structured session for discussion. The study was of a mixed design, including qualitative and quantitative components based on focus group interviews during the European A

Objectives. To assess the optimal stroke prevention treatment for patients with atrial fibrillation (AF) and a low-medium risk (<=4%) of stroke. Design. A total of 668 patients with persistent or permanent AF, without an indication for full dose and with adequate rate control on sotalol, were randomized to warfarin 1.25 mg + aspirin 75 mg daily (W/A, 334 patients) or no anticoagulation (C, 334 pa

The ADVEX project involved conducting extensive advection measurements at three sites, each with a different topography. One goal of the project was to measure the [CO2] balance under night-time conditions, in an attempt to improve NEE estimates. Four towers were arranged in a square around a main tower, with the sides of the square about 100 m long. Equipped with 16 sonic anemometers and [CO2] sa

Mouse apolipoprotein M (m-apoM) displays a 79% sequence identity to human apolipoprotein M (h-apoM). Both proteins are apolipoproteins associated with high-density lipoproteins, with similar anticipated biological functions. The structure of h-apoM has recently been determined by X-ray crystallography, which revealed that h-apoM displays, as expected, a lipocalin-like fold characterized by an eigh

Background: The expression of interleukin-1-receptor antagonist is reduced in pancreatic islets of patients with type 2 diabetes mellitus, and high glucose concentrations induce the production of interleukin-1(beta) in human pancreatic beta cells, leading to impaired insulin secretion, decreased cell proliferation, and apoptosis. Methods: In this double-blind, parallel-group trial involving 70 pat

BACKGROUND: The host response to urinary tract infection includes the production of different inflammatory mediators. We investigated the cellular localization and time course of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) expression in the mouse bladder and kidney after bacterial infection. METHODS: Experimental urinary tract infection in mice was established by intravesical

Popular Abstract in Swedish Svenskan är ett s.k. V2-språk, dvs. det tempusböjda verbet står på andra plats i en deklarativ sats (en påståendesats) oavsett vilken typ av led som står i satsens första position. V1-ordföljd, där det tempusböjda verbet alltså står först i satsen, förknippas normalt med interrogativa satser (frågesatser) av typen ja/nej-frågor, t.ex. "Kommer du på fredag?". Icke desto The topic of the present thesis is V1 declaratives in spoken Swedish. Such constructions constitute an interesting object for research due to the fact that Swedish is a V2 language where V1 word order is grammaticalized for yes/no questions. Hitherto we have lacked a thorough study of the phenomenon. Therefore this thesis aims at investigating V1 declaratives in spoken Swedish from different point

This paper presents the study of a mid-sized semi-closed oxy-fuel combustion combined cycle (SCOC-CC) with net power output around 108 MW. The paper describes not only the power balance and the performance of the SCOC-CC, but also the conceptual design of the SCOC turbine and compressor. A model has been built in the commercial heat and mass balance code IPSEpro to estimate the efficiency of semi-

“Is there a Nordic block, complete with a Nordic economic model and a special kind of Nordic welfare? Nordic collective security? Nordic values, Nordic sex, Nordic gloom? Undeniably the Nordic countries—the Scandinavian trio of Sweden, Denmark and Norway, plus Finland on the eastern flank and Iceland far north-west in the Atlantic—have a great many things in common. And undeniably the lure of the

Viral vector-mediated gene transfer has emerged as a powerful means to target transgene expression in the central nervous system. Here we characterized the efficacy of serotypes 1 and 5 recombinant adeno-associated virus (rAAV) vectors encoding green fluorescent protein (GFP) after stereotaxic delivery to the neonatal rat and minipig striatum. The efficiency of GFP expression and the phenotype of

Background Evaluating the external validity of clinical trials requires knowledge not only of the study population but also of a relevant reference population. The main aim of this study was to present data from a large, contemporary, population-based cohort of patients with colonic cancer. Methods Data on patients diagnosed between 2007 and 2011 were extracted from the Swedish Colon Cancer Regist

Real-time PCR is fast, sensitive, specific, and can deliver quantitative data; however, two disadvantages are that this technology is sensitive to inhibition by food and that it does not distinguish between DNA originating from viable, viable nonculturable (VNC), and dead cells. For this reason, real-time PCR has been combined with a novel discontinuous buoyant density gradient method, called flot

Background: Evidence points to a link between systemic lupus erythematosus (SLE) and an increased risk of lung cancer. Our objective was to provide a brief report of the lung cancer cases from an SLE cohort, with respect to demographics, histology, and exposures to smoking and immunosuppressive medications. Methods: Data were obtained from a multi-site international cohort study of over 9500 SLE p

Nyhetsbrev 2013 till dig som deltar i ett världsunikt projekt När Karin Lindskog fyllde 60 i höstas fick hon en inbjudan att medverka i GÅS-projektet. -Och det tackade jag utan tvekan ja till, säger Karin. Det här var ett jättefint erbjudande som jag inte ville missa. - Jag tycker det var en mycket bra dag jag fick tillbringa på GÅS-mottagningen i början av det här året och jag ser fram emot nästa

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2013.pdf - 2026-06-07

GÅS Nyhetsbrev för 2013 Nyhetsbrev 2013 till dig som deltar i ett världsunikt projekt Namn: Karin Lindskog Ålder: 60 år Bor: Malmö Deltagit i GÅS: En gång När Karin Lindskog fyllde 60 i höstas fick hon en inbjudan att medverka i GÅS-projektet. -Och det tackade jag utan tvekan ja till, säger Karin. Det här var ett jättefint erbjudande som jag inte ville missa. - Jag tycker det var en mycket bra dag

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2013_tg.pdf - 2026-06-07