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Characteristics of adolescents with poor mental health after bariatric surgery

BACKGROUND: About 20% of adolescents experience substantial mental health problems after bariatric surgery.OBJECTIVES: The aim of this study was to explore differences between adolescents with poor mental health (PMH) 2 years after surgery and those with average/good mental health.SETTING: Three university hospitals in Sweden.METHODS: Mental health and health-related quality of life were assessed

Lesson study as a vehicle for improving SEND teachers’ teaching skills

Purpose: Collaborative professional development for inclusive teaching is a limited area of research, although there is an extensive need for special educational needs and disabilities (SEND) teachers. Research findings of how teachers’ professional development can contribute to support the development of powerful learning situations for all students are presented in this special issue. The aim is

Gendered stereotype content for people with a nonbinary gender identity : [version 1; 1 peer review: 1 approved with reservations]

BackgroundGender stereotypes about women and men have a complementary structure, where women and men are seen as high/low in feminine characteristics and low/high in masculine characteristics. These stereotypes are related to representation within social roles, where beliefs about social role occupation influences which characteristics are associated with women or men. It is not known how people w

Public transport governance and working conditions of bus drivers : perspectives on accessibility for all in public transport

Although many efforts have been made to eliminate barriers in public transport worldwide, research shows that public transport is still often perceived as challenging, inconvenient, and inaccessible for many people with disabilities. A growing body of research points to several issues, relating to the spatial and temporal distribution of public transport, affordability, safety, and social barriers

Cross-sectional and prospective relations between dysfunctional cognitive beliefs and obsessive-compulsive symptoms during late childhood and early adolescence: a test of two aetiological models

BackgroundObsessive-compulsive symptoms (OCS) often emerge during childhood and adolescence, and two aetiological models have been proposed. According to the first model, maladaptive cognitive beliefs facilitate the transformation of transient intrusive thoughts into OCS. The second model suggests that dysfunctional cognitive beliefs develop in response to increased levels of OCS. Few studies have

Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis

Objective The investigation of complement factors in lupus nephritis (LN) in relation to treatment response and the impact of underlying genetics of C4. Methods Seventy-seven patients with active LN confirmed by a kidney biopsy and in whom second biopsies had been performed after immunosuppressive treatment were included. Complement factors C3, C4, C4d and C4d/C4 ratio were evaluated at the biopsy

Elastic nanobeam modelled using peridynamics - length scale effects

The traditional multiscale approach couples two models operating at different scales. An alternative modelling strategy, called peridynamics originally developed by [1], is to continualize the molecular dynamic models, thus replacing inhomogeneities present on smaller length scales by an enhanced continuum description on larger length scales resulting in a nonlocal reformulation of continuum mecha

TTV viral load as a marker for immune reconstitution after initiation of HAART in HIV-infected patients

PURPOSE: To investigate whether TT virus (TTV) viral load may be used as a surrogate marker for functional immune reconstitution in HIV-infected patients receiving highly active antiretroviral therapy (HAART).METHOD: Fifteen protease inhibitor-naïve HIV-infected patients were included in a longitudinal study. From each patient, three serum samples taken before HAART initiation and three samples ta

Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations

Retinitis pigmentosa (RP), an inherited blinding disease, is caused by a variety of different mutations that affect retinal photoreceptor function and survival. So far there is neither effective treatment nor cure. We have previously shown that poly(ADP-ribose)polymerase (PARP) acts as a common and critical denominator of cell death in photoreceptors, qualifying it as a potential target for future

Intra- and inter-rater reliability of the Sollerman hand function test in patients with chronic stroke

Purpose. To examine whether the Sollerman hand function test is reliable in a test-retest situation in patients with chronic stroke. Method. Three independent examiners observed each patient at three experimental sessions; two days in week I (short-term test-retest) and one day in week 4 (long-term test-retest). A total of 24 patients with chronic stroke (mean age; 59.7 years, mean time since stro

Validation of a new automated method for analysis of gated-SPECT images

We recently presented a new method for quantification of CArdiac FUnction - denoted CAFU - as the first step in the development of an automated method for integrated interpretation of gated myocardial perfusion single photon emission computed tomography (SPECT) images. The aim of this study was to validate CAFU in the assessment of global and regional function of the left ventricle. Quantitative g

Reduced mortality for women with mammography-detected breast cancer in east Denmark and south Sweden

The 5-year relative survival from breast cancer in Denmark is 10 percentage points lower than in Sweden. This difference has been demonstrated previously as being caused partly by more involved lymph nodes and larger tumours in Denmark. Sweden has had nationwide mammography-screening coverage since 1991, whereas this is still in its infancy in Denmark. In the search for an explanation for the rema

Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type I in breast cancer patients

Tumour angiogenesis and the levels of plasminogen activator inhibitor type I (PAI-I) are both informative prognostic markers in breast cancer. In cell cultures and in animal model systems, PAI-I has a proangiogenic effect. To evaluate the interrelationship of angiogenesis and the PAI-I level in breast cancer, we have evaluated the prognostic value of those factors in a total of 228 patients with p

Time dependence of the activity concentration ratio of red marrow to blood and implications for red marrow dosimetry.

BACKGROUND: The method for red marrow dosimetry in radioimmunotherapy, in the absence of specific activity uptake in red marrow, is based on the activity measured in the blood or plasma. The activity concentration ratio of red marrow to blood is then assumed to be constant. The aim of the current study was to determine whether this ratio varies with time after injection. METHODS: Measurements were

Composition of the bacterial population of refrigerated beef identified with direct 16S rRNA gene analysis and pure culture technique

The composition of the dominating population of freshly cut beef, and beef stored at 4 degrees C for 8 d, was studied by direct analysis of the 16S rRNA gene (PCR amplification, cloning and sequencing) and compared with pure culture technique where the isolates picked from the viable plate count were identified by sequencing of the 16S rRNA gene. The composition of the bacterial population was rec

Logistic regression model to distinguish between the benign and malignant adnexal mass before surgery: A multicenter study by the International Ovarian Tumor Analysis Group

Purpose To collect data for the development of a more universally useful logistic regression model to distinguish between a malignant and benign adnexal tumor before surgery. Patients and Methods Patients had at least one persistent mass. More than 50 clinical and sonographic end points were defined and recorded for analysis. The outcome measure was the histologic classification of excised tissues

Mental representations of important real-life decisions

Two studies investigated how decision makers characterize alternatives in important real-life decisions, which they themselves had made (to leave a partner, to choose an education and to choose a home). First, the participants indicated a very high degree of involvement in the decisions studied and about half of the participants gave maximum involvement ratings for the partner decision. Second, th

Changes in multi-segmented body movements and EMG activity while standing on firm and foam support surfaces.

Postural control ensures stability during both static posture and locomotion by initiating corrective adjustments in body movement. This is particularly important when the conditions of the support surface change. We investigated the effects of standing on a compliant foam surface using 12 normal subjects (mean age 26 years) in terms of: linear movements at the head, shoulder, hip and knee; EMG ac