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Planning and execution of large infrastructure projects benefit from detailed mapping of the subsurface through geophysical methods. However applying geophysical methods in an urban environment requires careful preparation to ensure success in areas where source of noise and present infrastructure may compromise the results. We present and discuss the results of a seismic investigation conducted i

GABA is the major inhibitory neurotransmitter in the CNS and changes in GABAergic neurotransmission affect the overall activity of neuronal networks. The uptake of GABA into synaptic vesicles is mediated by the vesicular GABA transporter (VGAT), and changes in the expression of the transporter directly regulate neurotransmitter release. In this work we investigated the changes in VGAT protein leve

The platelet-derived growth factor (PDGF) alpha and beta receptors undergo dimerization as a consequence of ligand binding. Depending on the PDGF isoform (PDGF-AA, -AB or -BB), homodimers or heterodimers of receptors are formed. In this study, we have used transfected porcine aortic endothelial cells, coexpressing cDNAs for the alpha receptor and the beta receptor at comparable levels, to investig

Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal

We consider the problem of seeking the maximum of a scalar signal using a swarm of autonomous vehicles equipped with sensors that can take point measurements of the signal. Vehicles are not able to measure their current position or to communicate with each other. Our approach induces the vehicles to perform a biased random walk inspired by bacterial chemotaxis and controlled by a stochastic hybrid

V&S Sundsvall (a part of V&S Vin & Sprit AB) is a Swedish company producing different alcoholic beverages, mainly for the Swedish market. The company has lately paid increasing attention to supply chain disruption risk issues. In another study, one of the authors (Paulsson 2007) developed a model, called the DRISC (Disruption Risks In Supply Chains) model, for the structuring, evaluati

Late glacial skeletal remains from mainly reindeer and wild horse, but also other species such as mountain hare, arctic fox and elk have been collected from kettle holes in Hässleberga, Scania. Bones from reindeer and wild horse have been radiocarbon dated to Allerød and Younger Dryas. Analysis of bone modifications has revealed several different actors and factors behind the accumulation of the s

In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.