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The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit.

The adapter protein APS has previously been shown to be involved in recruiting the ubiquitin E3 ligase c-Cbl to the insulin receptor, the platelet-derived growth factor b-receptor and the erythropoietin receptor, leading to increased degradation of the receptors and inhibition of mitogenesis. Here we demonstrate, by use of immobilized synthetic phosphopeptides corresponding to various autophosphor

Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents

Background - Although effective coverage of challenging coronary lesions has warranted the use of overlapping drug-eluting stents, the histopathological response to stent overlap is unknown. Methods and Results - The arterial reaction to overlapping Cypher or Taxus drug-eluting stents was examined in rabbits with bare metal stents, BxVelocity or Express, serving as controls. Single iliac artery ba

Comparison of quantitative ultrasound measurements in calcaneus with DXA and SXA at other skeletal sites: a population-based study on 280 children aged 11-16 years

We performed ultrasound measurements (QUS) of the calcaneus in a population-based setting on 280 healthy children, aged 11-16 years, from a small urban area in southern Sweden. The results are compared with dual-energy X-ray absorptiometry (DXA) measurements in the total body, the lumbar spine and the hip, as well as single-energy X-ray absorptiometry (SXA) of the forearm. Normative data and corre

Port-site metastases following robot-assisted laparoscopic surgery for gynecological malignancies.

Delayed colonisation of arable fields by spring breeding ground beetles (Coleoptera: Carabidae) in landscapes with a high availability of hibernation sites

Risk of hepatocellular carcinoma and cancers at other sites among patients diagnosed with chronic hepatitis B virus infection in Sweden.

Semiempirical modeling of abiotic and biotic factors controlling ecosystem respiration across eddy covariance sites

Surgical site infections in dermatologic surgery: etiology, pathogenesis, and current preventative measures.

Nocturnal body temperature in wintering blue tits is affected by roost-site temperature and body reserves.

Tumor Targeting Using Affibody Molecules: Interplay of Affinity, Target Expression Level, and Binding Site Composition.

Connectivity in Reed Warblers Acrocephalus scirpaceus between breeding grounds in Europe and autumn stopover sites in Iberia

Mechanistic Basis of Branch-Site Selection in Filamentous Bacteria

Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs.

Direct Site-Directed Photocoupling of Proteins onto Surfaces Coated with beta-Cyclodextrins

Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites

Multiproxy analysis of a new terrestrial and a marine Cretaceous-Paleogene (K-Pg) boundary site from New Zealand

Cleavage of fibromodulin in cartilage explants involves removal of the N-terminal tyrosine sulphate rich region by proteolysis at a site that is sensitive to MMP-13.

Integrity of cartilage fails in joint disease. The current work aimed to identify candidate active proteinases in joint diseases using an in vitro model for cartilage degradation induced by interleukin-1. A critical event in the process of cartilage destruction in joint disease is the failure of the collagen fiber network to maintain integrity. Proteins binding to the surface of the fibers are lik

Site-specific genetic divergence in parallel hybrid zones suggests non-allopatric evolution of reproductive barriers

Consensual Approaches to Siting Controversy

Small-Scale Reforming for On-Site Hydrogen Supply