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Cocaine- and amphetamine-regulated transcript-derived peptides (CARTp) and corticotropin-releasing factor (CRF) alter feeding and gastrointestinal function after central administration, and the gastric inhibitory effects are mediated through CRF. We hypothesized that dorsal hindbrain effects of CARTp on gastric emptying are mediated by the vagus nerve and that the dorsal vagal complex (DVC) is a s

Background: Oxidation of LDL is associated with generation of autoantibodies against a large number of different aldehyde-modified peptide sequences in apo B-100. Autoantibodies recognizing peptide sequences in the LDL receptor-binding region of apo B-100 could potentially affect both cholesterol metabolism and atherosclerosis. The aim of the present study was to determine physiological effects of

The adapter protein APS has previously been shown to be involved in recruiting the ubiquitin E3 ligase c-Cbl to the insulin receptor, the platelet-derived growth factor b-receptor and the erythropoietin receptor, leading to increased degradation of the receptors and inhibition of mitogenesis. Here we demonstrate, by use of immobilized synthetic phosphopeptides corresponding to various autophosphor

Electrification of energy demand is seen as one of the key elements of energy transition toward decarbonisation. E-mobility is one main side of the electrification process, and it is considered as a crucial way to reduce the emissions of the transport sector. A core element for a widespread adoption of electric vehicles (EVs) is the deployment of the charging infrastructure, and installing a micro

I snart 500 år har människan använt sig av diverse optiska instrument för att betrakta sådant som inte är möjligt att se med blotta ögat. Teleskop har använts för att studera himlakroppar och mikroskop för att exempelvis undersöka små biologiska beståndsdelar. Det finns idag många olika metoder inom optisk mikroskopi men samtliga följer en liknande grundprincip. Objektet som ska avbildas exponerasSeveral significant pathogenic bacteria exhibit surface proteins that bind human antibodies, preventing them from being recognized by the human immune system. These bacteria are thus protected from elimination and can survive in the host organism. One common such bacteria is the Streptococcus pyogenes that exhibits the antibody binding M protein on its surface. Streptococcus pyogenes causes more t

Luminiscensdatering är en väletablerad dateringsmetod inom geologisk och arkeologisk forskning. Dock är användandet av luminiscensdatering, mer specifikt optiskt stimulerad luminiscens (OSL), fortfarande underrepresenterat inom norsk arkeologi. Denna studie ämnar utreda lämpligheten av denna dateringsmetod som ett användbart alternativ för utgrävningar av Stenålderslokaler på den norska kusten. De

Cultural tourism and cultural heritage management, while distinct disciplines with differing foci, are also inherently intertwined. However, conflicts between the two often arise due to the diverse number of stakeholders and interests involved in either the travel industry or the conservation and protection of cultural heritage. Despite this, cultural tourism can greatly benefit the conservation o

Popular Abstract in Swedish Melatonin är ett hormon som produceras i, och frisätts från pinealorganet hos ryggradsdjur. Melatoninets viktigaste uppgift är att till hjärnan förmedla signalen om nattens längd, d.v.s vilken årstid det är. Produktionen och frisläppningen sker rytmiskt med den högsta nivån under natten. Melatoninet transporteras ut i kroppen via blodet och binder till särskilda mottaga