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Finding potential sites for small-scale hydro power in Uganda : a step to assist the rural electrification by the use of GIS : a minor field study

Populärvetenskaplig sammanfattning: Mer än två miljarder människor, mestadels i utvecklingsländer, saknar tillgång till moderna energikällor eller elektricitet. Behovet av rena, effektiva, pålitliga och ekonomiskt överkomliga energitjänster är en viktig fråga i utvecklingsländer, särskilt för landsbygden, där merparten av befolkningen bor. Förnyelsebara energikällor i form av småskaliga vattenkrafOver 2 billion people, mostly in developing countries, have no access to modern fuels or electricity. The necessity of clean, efficient, reliable and affordable energy services is a crucial issue in developing countries, especially in the context of rural areas where the majority of the people lives. Renewable energy sources in shape of small-scale hydropower systems are a complement or alternativ

Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases

Tec family protein tyrosine kinases (TFKs) play a central role in hematopoietic cellular signaling. Initial activation takes place through specific tyrosine phosphorylation situated in the activation loop. Further activation occurs within the SH3 domain via a transphosphorylation mechanism, which for Bruton's tyrosine kinase (Btk) affects tyrosine 223. We found that TFKs phosphorylate preferential

Accurate Predictions of Nonpolar Solvation Free Energies Require Explicit Consideration of Binding-Site Hydration

Continuum solvation methods are frequently used to increase the efficiency of computational methods to estimate free energies. In this paper, we have evaluated how well such methods estimate the nonpolar solvation free-energy change when a ligand binds to a protein. Three different continuum methods at various levels of approximation were considered, viz., the polarized continuum model (PCM), a me