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The fundamental question in this work concerns the ideal relation between asceticism and society in a 5th c. writing (C.E.), the Philotheos Historia (PH), written in elaborate Greek by the learned bishop of Cyrrhus, Theodoret. This collection of saints’ stories tells about the lives of a number of ascetics who lived in the Eastern part of the Roman Empire, many of them close to Antioch. As these n
Interactions between metals and natural organic matter (NOM) are of great environmental importance and one of the key factors influencing hydrolysis, solubility, and speciation of the metals. However, studying geochemically relevant metals like Al, Fe, and Cu is sometimes associated with analytical problems; for example Fe and Cu are both redox active. Gallium (Ga) is a non-redox active metal that
This thesis focuses on cognitive impairment in Out-of-Hospital Cardiac Arrest (OHCA) survivors with the main aim to evaluate possible effects by targeted temperature management. Secondary aims are to describe the prevalence of cognitive impairment in a large group of OHCA-survivors, the related symptoms of psychological distress and the actual effect of cognitive impairment for the patient’s abili
Popular Abstract in Swedish Hjärt-kärlsjukdom är en av västvärldens stora folksjukdomar. I Sverige drabbas årligen cirka 10 000 personer av plötsligt hjärtstopp. Den vanligaste orsaken är att en akut hjärtinfarkt orsakar ett ”elektriskt kaos” i hjärtat. Vid ett hjärtstopp upphör blodförsörjningen till hjärnan, vilket leder till medvetslöshet inom några sekunder och inom några få minuter börjar hjäThis thesis focuses on the prognostic value of electroencephalography(EEG) in comatose patients resuscitated after cardiac arrest (CA), using both simplified continuous EEG monitoring (cEEG) and routine EEG. Background: Comatose survivors are admitted to an intensive care unit (ICU) to support vital functions. Postresuscitation care includes target temperature management (TTM) for 24 hours. The d
Popular Abstract in Swedish Förekomsten av hudcancer ökar i ljushyade befolkningsgrupper och hudcancer tillhör de cancergrupper som ökar mest i Sverige. De tre vanligaste formerna av hudcancer är basalcellscancer, skivepitelcancer och malignt melanom. Under 2013 utgjorde skivepitelcancer och malignt melanom ca 16 % av alla cancerfall som rapporterades in till Svenska Cancerregistret; över 6 000 faSkin cancer incidence is increasing in fair-skinned populations. The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. The purpose of this thesis was to evaluate different aspects of the preoperative diagnosis of skin cancer. Th
Background The leucine-rich repeat kinase 2 gene (LRRK2) harbours highly penetrant mutations that are linked to familial parkinsonism. However, the extent of its polymorphic variability in relation to risk of Parkinson's disease (PD) has not been assessed systematically. We therefore assessed the frequency of LRRK2 exonic variants in individuals with and without PD, to investigate the role of the
Background Immunotherapy targeting the amyloid beta (A beta) peptide is a potential strategy to slow the progression of Alzheimer's disease. We aimed to assess the safety and tolerability of CAD106, a novel active A beta immunotherapy for patients with Alzheimer's disease, designed to induce N-terminal A beta-specific antibodies without an A beta-specific T-cell response. Methods We did a phase 1,
Vehicle design is characterized by a high number of compromises. The special role of human factors in the process is to ensure that the compromises do not occur at the expense of the driver and passengers. Within the automotive industry there is a need for the development of inexpensive and efficient ergonomic tools, facilitating a fast and cost effective car development process as well as discuss
Recent investigations of the DNA interactions with cationic surfactants and catanionic Mixtures are reviewed. Several techniques have been used such as fluorescence microscopy, dynamic light scattering, electron microscopy, and Monte Carlo simulations. The conformational behaviour of large DNA molecules in the presence of cationic surfactant was followed by fluorescence microscopy and also by dyna
Popular Abstract in Swedish Läkaren har en viktig roll när det gäller att tillförsäkra människor vård på lika villkor. Mötet mellan läkaren och patienten präglas alltid av maktobalans. Studier världen över visar att invandrarpatienter är en sårbar grupp eftersom invandrare generellt har sämre tillgång till vård, sämre förutsättningar för hälsa och sämre hälsotillstånd jämfört med majoritetspopulatPhysician and patient do not meet as equals in the consultation. It is the responsibility of the physician to actively work for better communication in order to provide equitable health care for all individuals. Immigrant patients are a vulnerable group, shown in studies all over the world to have less access to care, fewer opportunities for health, and poorer health compared to majority populatio
Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin
The Proton Exchange Membrane (PEM) fuel cell has been investigated for a long time, and is regarded as a new energy source for various applications, such as portable, stationary and automotive ones. However, due to the shortage of the infrastructure in the society, the high cost, the difficulty of the water/thermal management, etc., practical systems have not reached the general public, yet. Of t
Popular Abstract in Swedish För att få svar på frågan om prostarnas lojalitet i samband med ”försvenskningen” av Lunds stift på 1680-talet, har jag använt lokalt material såsom räkenskaper och längder. Jämfört med den tidigare forskningen har mer preciserade och delvis annorlunda resultat presenterats, både vad gäller prostarnas lojalitet och ”försvenskningens” intensitet. Prostarna var ambivalentAfter the Peace of Roskilde in 1658, the territory that Sweden had acquired was to be incorporated into the rest of the country. A 'Swedification' of the church and the services did not begin until 1680, when a new bishop took up his duties in the Lund diocese. Previous research has been concentrated around the events on the national and diocese levels. The aim of this study is to use more local m
Several beneficial effects have been connected with dietary fibre. Insoluble fibre has a good faecal bulking capacity, whereas soluble and viscous dietary fibre has been shown to have beneficial effects on carbohydrate and lipid metabolism. Fruit and vegetables provide about one third of the dietary fibre intake in Northern Europe and more than half in Mediterranean countries. These food items are
Popular AbstractSyftet med avhandlingen är att undersöka på vilket sätt teater med ungdomar, enligt ungdomarnas egna erfarenheter och utsagor om det, utgör en kollektiv bildningsprocess. I avhandlingens syfte ingår att analysera hur en teaterföreställning växer fram och att skapa förståelse för vad som sker mellan olika aktörer, främst mellan ungdomar och ledare.Forskningsfenomenet, unga människorThe objective of this research project is to investigate in what way young people's theatre playing, according to their own experiences, constitute a collective educational process. Also, the project aims at understanding the interaction between the different actors, and particularly between the young amateurs and their leaders. Young people's acting in this research project is understood from a p
Popular Abstract in English Lions (Panthera leo) have become known to be synonymous with wild Africa since its extinction from most parts of its former range (Europe, Asia and Southern America). Few people realize that anthropogenic activities have caused habitat loss, fragmentation and reduction in size to the lions, forcing them to the brink of extinction. Whenever out in nature, most tourists tHigh growth rate in human populations, agricultural developments and industrialization have impinged negatively on the natural habitats of most large carnivores, causing fragmentation, isolation and consequently reduction in population size. Lions (Panthera leo) that once roamed most parts of Southern Europe, Asia, the Middle East, North America, northern part of South America and most parts of Af
En kurs kan betraktas som en pedagogisk process avsedd att hjälpa de deltagande studenterna att utveckla den kunskap och förståelse, färdighet och förmåga samt den värderingsförmåga och det förhållningssätt som kursen avser. I linje med detta ska kvalitetsarbetet inom Lunds universitets utbildningsverksamhet fokusera studenternas lärande, där lärandemål, undervisning och andra läraktiviteter samt
The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. In this thesis chemical crosslinking and mass spectrometric mapping of crosslinked peptides has been used to investigate the
Popular Abstract in Swedish En insekts rörelsemönster i en värld av dofter Jag har videofilmat hur en marklevande insekt, Protaphorura armata, rör sig på en plan yta, hur de gör när de stöter på hinder, dofter från mat, artfränder och fiender. Jag har också använt matematiska modeller för att beskriva deras rörelsemönster. P. armata är en s.k. hoppstjärt men saknar förmågan att hoppa som flertaleMovement and dispersal are important determinants of the spatial distribution and persistence of animal populations in a heterogeneous environment. I studied the small-scale movement pattern of a soil-living insect, Protaphorura armata (Collembola) by using a video-equipment. I added chemical cues, food and conspecifics to their environment and evaluated the effects of external cues on the movemen
