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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3
In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
Gas chromatographic analyses coupled with electro‐antennographic detection indicated that (Z,E)‐9,11‐tetradecadienyl acetate (Z,E‐9,11–14Ac) is a pheromone component of the cone pyralid Dioryctria abietella. Gas chromatographic − mass spectrometric analyses confirmed the presence of a tetradecadienyl acetate with mass spectrum and retention index identical to Z,E‐9,11–14Ac. A receptor cell sensiti
Popular Abstract in Swedish Protein H - ett bakteriellt ytprotein med förmåga att binda till olika proteiner hos människa Bakgrund I vårt dagliga liv omges vi av bakterier av många olika slag. Flertalet av dessa är normalt ofarliga och många utgör den så kallade normalfloran hos människa. En del bakterier kan under vissa förhållanden ge upphov till infektion och sjukdom, men för att åstadkomma d
ABSTRACT Introduction: Scientists from many disciplines have studied population, church and burials from the Early Medieval churchyard Västerhus/Westerhus in Middle Sweden. Archaeology, anthropology, odontology and demography of this population have been investigated. The present project group has, above all, investigated teeth, bones and bone chemistry. But also many archaeological questions have
Att parterna vid en avtalsförhandling förhandlar på egen risk är en självklar utgångspunkt. Men redan under avtalsförhandlingar kan skadeståndsansvar uppkomma enligt rättsfiguren culpa in contrahendo. Culpa in contrahendo är en sammanfattande beteckning på olika klandervärda beteenden vid avtals ingående. Denna uppsats behandlar förutsättningarna för skadeståndsansvar när förhandlingarna inte lett
dmrr2427 557..567 Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY Kendra Vehik1* Steven W. Fiske1 Chad A. Logan1 Daniel Agardh2 Corrado M. Cilio2 William Hagopian3 Olli Simell4 Merja Roivainen5 Jin-Xiong She6 Thomas Briese7 Sami Oikarinen8 Heikki Hyoty8,9 Anette-G. Ziegler10 Marian Rewers11 Ake Lernmark2 Beena Akolkar12 Jeffr
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/27%2006032016_679_27_Vehik_DMRR_2013.pdf - 2026-06-27
