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To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

The Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz

Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We

Abstract in French Cette contribution décrit l’aide potentielle que le concept de table interactive apporte à certaines tâches du concepteur en mécanique. Le travail de recherche présenté n’en est qu’à sa genèse. La problématique est la suivante : une fois la faisabilité d’une idée de produit (le concept) est prouvée, le concepteur développe l’architecture et les composants du produit (embodiment This paper describes the potential help that the interactive desktop concept can bring to the execution of embodiment design tasks. The presented project is still in its infancy. The research framework is the following: once a product concept has been approved, the mechanical design engineer develops the product architecture and product part (also called embodiment design). Sketches at that level

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit

Microsoft Word - Jiffy_press_eng.docx JULIA SJÖLIN JIFFY 3 APRIL–18 APRIL 2020 Julia once told me about a project which point of departure was to collect glass that had been formed by lightning striking sand. The project never happened but the glass and the discharge of energy from which the lightning emerge, still plays a central role in Julia Sjölin's practice and consequently in this exhibition

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/jiffy_press_release_english.pdf - 2026-07-05

Popular Abstract in French La rencontre des sexes est une nécessité pour la majeure partie des organismes appartenant au règne animal. Au cours de l’évolution, différentes modalités sensorielles, comme la vue, l’ouie et l’odorat, sont apparues et ont été perfectionnées pour permettre aux organismes de percevoir l’environnement qui les entourent, et de communiquer. Reconnaître ses pairs de ses enneChemical communication by means of sex pheromones is central to the mating systems of a wide range of organisms. Because reproductive isolation is often based on pheromone differences, understanding how pheromones diverge is necessary for a complete comprehension of the speciation process. Moths (Insecta: Lepidoptera) contributes highly relevant examples to the theory of speciation because subtle

Je connais deux filles, elles s'appellent Thea et Bea. Elle sont les meilleurs amis. Thea est mince avec des cheveux marron et Bea est grosse avec des cheveux blondes. Une jour Thea et Bea ont decidé de faire un voyage en Italie, Thea qui est folle des garcons a rêvé des italiens, avec ses cheveux noir est ses sourires elegantes. Bea a un peau blanc et voulait se bronzer dans la plage. Mais bien s

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_d/Dagmar.txt - 2026-07-04

Je connais deux filles, elles s'appellent Thea et Bea. Elle sont les meilleurs amis. Thea est mince avec des cheveux marron et Bea est grosse avec des cheveux blondes. Une jour Thea et Bea ont decidé de faire un voyage en Italie. Thea qui est folle des garcons a rêvé des italiens, avec ses cheveux noir est ses sourires elegantes. Bea a un peau blanc et voulait se bronzer dans la plage. Mais bien s

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_longitudinal/dagmar/Texte_3.txt - 2026-07-04

This article outlines an experimental and numerical study on compatibility between flooring materials and concrete. Full-scale cylinders and slabs with different kinds of floorings were tested. The cylinders were studied in the laboratory, and cured in the same way as at a building site. The slabs were ground, treated with plaster and/or untreated (reference concrete). These slabs were water-cured

Program ESSUG:s användardagar 2022 via Zoom Tisdagen den 26 april (EBSCO deltar under denna eftermiddag) 13.00-13.05 Välkomna! 13.05-13.45 Presentation the new GOPAC/Global OPAC (Claus Wolf, Manager Library Service Engineer team) 30 min + 10 min frågor 13.45-13.50 Paus 13.50-14.20 Continued roll out and enhancements of the new EDS interface. Project updates (PM- team) 20 min + 10 min frågor 14.20-

https://www.ub.lu.se/sites/ub.lu.se/files/2022-05/Program%20ESSUG%20anv%C3%A4ndardagar%2026-27%20april.pdf - 2026-07-05

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl

Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser

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https://www.pi.lu.se/sites/pi.lu.se/files/julkort_2017_5_150.pdf - 2026-07-05