Filetype
Structural compromise of the tumor suppressor gene, PTEN occurs in 10% of melanoma specimens and loss of PTEN expression through DNA methylation of the PTEN promoter region has also been reported in a number of other malignancies. However, the role of PTEN promoter methylation in melanoma is not well understood. We thus sought to elucidate the prevalence of PTEN promoter methylation in melanoma sp
BACKGROUND: Risk of coronary heart disease (CHD) in cancer patients has not been thoroughly investigated. The aim of the present study was to examine whether there is an association between cancer and first hospitalisation for CHD. METHODS: All individuals in Sweden with a diagnosis of cancer between 1st January 1987 and 31st December 2008 were followed for first hospitalisation for CHD. The refer
OBJECTIVE: Gene expression alterations, especially in target tissues of insulin, have been associated with type 2 diabetes (T2D). Here, we examined if genes involved in oxidative phosphorylation (OXPHOS) show differential gene expression and DNA methylation in pancreatic islets from patients with T2D compared with non-diabetic donors. DESIGN AND METHODS: Gene expression was analyzed in human panc
Background Balloon kyphoplasty is a minimally invasive procedure for the treatment of painful vertebral fractures, which is intended to reduce pain and improve quality of life. We assessed the efficacy and safety of the procedure. Methods Adults with one to three acute vertebral fractures were eligible for enrolment in this randomised controlled trial at 21 sites in eight countries. We randomly as
Respiratory symptoms among hairdressers are often ascribed to the use of bleaching powders that contain persulfate salts. Such salts can act as allergens and airway irritants but the mechanisms behind the negative health effects are not fully known. In order to understand why some hairdressers experience respiratory symptoms during, and after, sessions of hair bleaching, it is of importance to cha
Background Safety data on cancer risks following tumour necrosis factor a inhibitors (TNFi) in patients with spondyloarthritis (SpA) (here defined as ankylosing spondylitis (AS), undifferentiated spondarthropaties (SpA UNS), psoriatic arthritis (PsA)) are scarce. Our objective was to assess risks for cancer overall and for common subtypes in patients with SpA treated with TNFi compared with TNFi-n
Malawi Polyomavirus Is a Prevalent Human Virus That Interacts with Known Tumor Suppressors Christian Berrios,a,b Joonil Jung,c Blake Primi,d,e Michael Wang,f Chandrasekhar Pedamallu,a,c Fujiko Duke,a,c Christina Marcelus,a Jingwei Cheng,a,g Robert L. Garcea,d,e Matthew Meyerson,a,c,h James A. DeCaprio,a,b,g the TEDDY Study Group Department of Medical Oncology, Dana-Farber Cancer Institute, Boston,
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/38%2006032016_679_38_Berrios_JVirology_2014.pdf - 2026-07-17
Introduction: Cyclic adenosine 3’5’-monophosphate (cAMP) and cyclic guanosine 3’5’-monophoshpate (cGMP) are critical intracellular second-messengers involved in the transduction of a wide variety of extracellular stimuli, including peptide hormones, growth factors, cytokines, neurotransmitters and light. These messengers modulate many fundamental biological processes, including growth, differentia
Energy efficiency and environmental questions have gained increased attention over the last decade. In combination with global warming and increasing cooling demands, the Swedish market for combined heating and cooling solutions such as ground source heat pumps expands. As it currently stands, the multi-family building market is highly dominated by district heating, while the market share of combi
Process-based biosphere models, which formulate biophysical ecosystem processes, provide a mechanistic framework for understanding terrestrial carbon dynamics. In contrast, data-driven approaches, e.g., upscaling eddy covariance (EC) fluxes using satellite observations and machine learning, offer empirical estimates. These complementary methods often diverge significantly, particularly in estimati
PURPOSE: To estimate the excess healthcare use and work disability attributable to knee osteoarthritis (OA) in the first five years following diagnosis.METHODS: Among individual aged 40-80 years who resided in Skåne on 31st December 2008, we identified those with a main diagnosis of knee OA during 2009-2014 and no previous diagnosis of any OA from 1998 (n=16,888). We created a comparison cohort ma
Background: Lemierre syndrome is characterized by head/neck vein thrombosis and septic embolism usually complicating an acute oropharyngeal bacterial infection in adolescents and young adults. We described the course of Lemierre syndrome in the contemporary era. Methods: In our individual-level analysis of 712 patients (2000–2017), we included cases described as Lemierre syndrome if these criteria
Background: Understanding the factors influencing movement is essential to forecasting species persistence in a changing environment. Movement is often studied using mechanistic models, extrapolating short-term observations of individuals to longer-term predictions, but the role of weather variables such as air temperature and solar radiation, key determinants of ectotherm activity, are generally
Varje år släpps ungefär 10 gånger mer koldioxid ut av mikroorganismer som lever i jorden vi går på, jämfört med utsläppen som kommer från fossila bränslen. Som tur är tar växter upp ungefär lika mycket koldioxid från atmosfären som mikroorganismerna släpper ut, så de balanserar varandra. En viktig fråga är vad som händer med balans mellan växter och mikroorganismer om klimatet blir varmare. Om växThe aim with this thesis work was to study microorganisms response to milder winters, different seasons, and altered temperature. Winter warming treatments were established in a semi-natural temperate grassland, simulating mild winters for two years. We found that arbuscular mycorrhizal (AM) fungi received more carbon (C) from the plants after experiencing milder winters. The amount of plant-deri
Gastric cancer trends seem to follow improvements in the environment of blue-collar workers, but the etiological role of occupational exposures in gastric carcinogenesis is scantily investigated. The risk of gastric adenocarcinoma in 10 common occupational industries, and particularly the long-term effects of asbestos, organic solvents, impregnating agents, insecticides, and herbicides, were evalu
Location is everything and the geographical distribution of populations will make them differentially affected by global warming. Sweden’s north to south orientation presents a great frame for studying the effect of latitudinal climate change. We present a long-term study on the migratory behaviour of two populations of Willow Warbler subspecies (southern Phylloscopus trochilus trochilus and north
Bästa resultat får du om du öppnar den här PDF-portföljen i Acrobat X eller Adobe Reader X eller senare. Hämta Adobe Reader nu! http://www.adobe.com/go/reader_download_se 2014-09-19 1 Lunds universitet /Rektor/2014-09-19 Rektorinformation 2014-09-19 UTBILDNING, FORSKNING OCH INNOVATION SEDAN 1666 Lunds universitet /Rektor/2014-09-19 Aktuellt 1 • Internationella och nationella studenter har välkomn
https://www.lu.se/sites/www.lu.se/files/us_ejsign_protokoll_bilagor_140919_1.pdf - 2026-07-17
Microsoft Word - Remembering Europe.doc REMEMBERING EUROPE’S EXPELLED PEOPLES OF THE TWENTIETH CENTURY Edited by: Barbara Törnquist-Plewa Bo Petersson CFE Conference Papers Series No. 4 Lund 2009 2 The CFE Conference papers series is published by The Centre for European Studies (CFE) at Lund University: © 2009 The Centre for European Studies at Lund University and the authors Editors: Barbara Törn
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfecp4.pdf - 2026-07-17
Fuzzy Borders and Postcolonial Forgotten Zones: The Case of Indo-Bangladeshi Enclaves Fuzzy Borders and Postcolonial Forgotten Zones: The Case of Indo-Bangladeshi Enclaves AMRITA GHOSH | SASNET PUBLICATIONS REPORT 2021:2 SASNET | LUND UNIVERSITY Author: Amrita Ghosh Information about Author: Amrita Ghosh has a Ph.D in literature and Partition Studies from Drew University, USA, and a postdoc from L
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/2021-02/SASNET_Rapport_Ghosh_2021-02.pdf - 2026-07-17
doi:10.1016/S1044-7431(03)00097-6 A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population Malin Parmar,* Charlotta Skogh, and Ulrica Englund1 Wallenberg Neuroscience Center, BMC A11, Section of Neurobiology, Lund University, SE-221 84 Lund, Sweden Received 2 January 2003; revised 12 March 2003; accepted 17 March 2003 Abst
