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OBJECTIVES: To analyse the neuropathological changes behind clinically defined dementia with Lewy bodies (clinDLB) compared with clinically diagnosed Alzheimer's disease (clinAD). METHODS: The prevalence of neuropathological findings in 48 clinDLB and 45 clinAD cases was compared. Sixteen clinDLB and 10 clinAD cases were reassessed with alpha-synuclein staining for Lewy bodies (LB). RESULTS: Alzhe
A unified approach is given which allows one to construct examples of all three cases resulting from a generalization of the classical Weyl limit point limit circle analysis, for differential equations as well as for difference equations.
Invasive procedures can be performed safely in children with haemophilia due to the availability of factor VIII/IX for patients without inhibitors. Most guidelines are based on the experiences in adults, but still there is no established consensus on the optimal factor levels or duration of replacement therapy for adults undergoing surgery. Few publications have focused on surgery in children with
Solar energy conversion in photovoltaics or photocatalysis involves light harvesting, or sensitization, of a semiconductor or catalyst as a first step. Rare elements are frequently used for this purpose, but they are obviously not ideal for large-scale implementation. Great efforts have been made to replace the widely used ruthenium with more abundant analogues like iron, but without much success
Popular Abstract in English Nowadays, the majority of energy production comes from combustion which is universally linked to daily human activities. Public awakening of the environmental effects of combustion pollution evokes extensive research activities in improving combustion efficiency and reducing pollutant production. Development of combustion processes also includes the use of renewable bioThe work presented in the thesis concerns the developments of laser-based diagnostics and its application to the study of turbulent premixed combustion. The diagnostic developments, mainly concerned with planar laser-induced fluorescence (PLIF), are intended to provide instantaneous visualization of the key species originating from the combustion processes involved in the burning of hydrocarbons
The inverse of the standard estimate of covariance matrix is frequently used in the portfolio theory to estimate the optimal portfolio weights. For this problem, the distribution of the linear transformation of the inverse is needed. We obtain this distribution in the case when the sample size is smaller than the dimension, the underlying covariance matrix is singular, and the vectors of returns a
In 1996 the European Union adopted the Seveso II Directive. The Directive stated actions to be taken in the process industry in order to prevent and limit the impact of serious chemical accidents. In the Directive it is clearly stated that domino effects shall be considered, but the level of detail required is not specified. Due to that fact and the high degree of complexity linked to domino e
It is becoming more and more common to exercise regularly, and with this new fitness trend follows more exercise applications to our smartphones. Applications aiming to help us exercise by structuring and logging our training. The user experience for these applications can be a little bit dull, since most of the applications depend on the user following instructions and entering input of the resul
This study investigates the importance of implant surface topography on soft tissue response. The tissue response in the rat abdominal wall to discs of low density polyethylene with smooth to coarse surfaces was evaluated after one, six or 12 weeks. Capsule thickness and immunohistochemical quantification of monocytes-macrophages were used as measures. The macrophage specific antibody ED1 was used
Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that the PDZ-binding motif of Claudin-2 is necessary for anchorage-independent growth of cancer cells and is required for liver metastasis. Several PDZ domain-containing proteins were identified that interact with the PDZ-binding motif of Claudin-2 in liver metastatic breast can
Although invasive species are recognized as a major threat to freshwaters, little is known about how future climate warming will affect the success of invaders. Ecosystems are also often simultaneously impacted by multiple, potentially interacting, invading species and the management of species invasions can be incredibly difficult. Sensitive methods such as environmental DNA (eDNA) metabarcoding,
