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Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on

It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Meddelanden från HT-biblioteken | maj 2025 Meddelanden från HT-biblioteken | maj 2025 Publicerad den 15 maj 2025 Foto: Kristina Carlsson Sköna maj, välkommen! I månadens nyhetsbrev hittar ni bibliotekens öppettider till Kristi himmelsfärds- och nationaldagshelgerna och alla våra nyförvärv i april. Ett hett tips för era uppsatsskrivande studenter är en öppen workshop om att publicera sin uppsats i

https://www.htbibl.lu.se/article/meddelanden-fraan-ht-biblioteken-maj-2025 - 2025-11-05

Questions about institutional stability and change are critically important for any understanding of political institutions. The field of Historical institutionalism in political science has described, studied and theorized institutions for decades. One of the most recurring concepts utilized in the explanation of institutional stability is path dependence, describing theoretical and empirical mec

Meddelanden från HT-biblioteken | maj 2025 Meddelanden från HT-biblioteken | maj 2025 Publicerad den 15 maj 2025 Foto: Kristina Carlsson Sköna maj, välkommen! I månadens nyhetsbrev hittar ni bibliotekens öppettider till Kristi himmelsfärds- och nationaldagshelgerna och alla våra nyförvärv i april. Ett hett tips för era uppsatsskrivande studenter är en öppen workshop om att publicera sin uppsats i

https://www.htbibl.lu.se/article/meddelanden-fraan-ht-biblioteken-maj-2025/ - 2025-11-08