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Purpose: In patients with hemophilia B, treatment with extended half-life (EHL) recombi-nant factor IX allows for longer dosing intervals while providing equal or superior bleeding protection compared with standard half-life products. This enables flexible, individualized treatment schedules, which reduce the burden of prophylaxis and improve patient outcomes. This analysis compared the efficacy o

The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was

Kalendarium Länk till RSS 22 oktober 2025 13:00 till 13:20 | Visning Öppen visning: Sten- och bronsålderssalen 22 oktober 2025 15:00 till 15:20 | Visning Guided tour: The Ethnographical Hall – An introduction to “Treasures from five Continents” 23 oktober 2025 13:00 till 13:20 | Visning Öppen visning: Medeltidssalarna – Den medeltida Mariakulten 23 oktober 2025 15:00 till 15:20 | Visning Guided to

https://www.historiskamuseet.lu.se/om-museet/nyheter - 2025-10-21

Published original articles in referee-assessed international journals Han, G., Alfredsson, E., Cox, L., & Psouni, E. (in press). Variation in coparenting quality in relation to child age: Links to coparents’ relationship satisfaction and education. Scandinavian Journal of Psychology. Angelöw, A.*, Niwhede, V.*, & Psouni, E. (2023). Evaluating trauma-informed training for foster parents - a contro

https://www.psy.lu.se/forskning/utvecklingspsykologi/publications-elia-psouni - 2025-10-21

Litteraturlista Bedömning och betygssättning Artiklar och böcker Carlgren, Ingrid., Forsberg, Eva., & Lindberg, Viveca. (2009). Perspektiv på den svenska skolans kunskapsdiskussion. (s. 11–39). Stockholms universitetsförlag. https://www.diva- portal.org/smash/get/diva2:371489/FULLTEXT01.pdf [ca 28 s.] Green, Jenny. (2018). Återkoppling för lärande och utveckling av undervisningen. Skolverket. http

https://www.mhm.lu.se/sites/mhm.lu.se/files/2021-06/Litteraturlista%20Bedo%CC%88mning%20och%20betygssa%CC%88ttning%20ht%2021.pdf - 2025-10-23

https://www.psy.lu.se/sites/psy.lu.se/files/psye26ht14_0.pdf - 2025-10-23

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti