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Purpose/Objective(s): To report the efficacy and utility of PSMA-based molecular targeted imaging in localized prostate cancer using 111In-J591 SPECT and 89Zr-J591 immuno-PET.Materials/Methods: Initiated in 2010, two sequential phase 0 prospective studies were performed on a total of 19 patients evaluating the roles of 111In-J591 SPECT and 89Zr-J591 immuno-PET. All patients had a baseline MRI foll

Nowadays, organizations pursue their aims in a context of distributed collaboration, creating a need not only for supporting ICT systems, but for a hu-man-centred focus in which individual and group sense-making and learning are supported by appropriate toolsets. We argue that development of such toolsets re-quires an open systems approach. This paper discusses one example: non-competitive benchma

This paper addresses Test Application Time (TAT) reduction for core-based 3D Stacked ICs (SICs). Applying traditional test scheduling methods used for non-stacked chip testing where the same test schedule is applied both at wafer test and at final test to SICs, leads to unnecessarily high TAT. This is because the final test of 3D-SICs includes the testing of all the stacked chips. A key challenge

Oath-taking during Roman Antiquity constitutes a telling example of how words and matter interplay and relate to one another. Ancient Latin literature provides a myriad of representations of oaths sworn, both fictive and supposedly historical, where matter somehow figure in the procedure. In this study, a selection of personal oaths from Roman literature are explored in terms of materiality and ag

More than ever, Machine Learning (ML) as a subfield of Artificial Intelligence (AI) is on the rise and is finding its way into safety-critical software applications. However, when it comes to quality assurance (QA) and trustworthiness, integrating ML models into software comes with challenges that may not be apparent at first glance. The European Union (EU) aims to tackle this problem with new reg

Seismic Structural Health Monitoring (S2HM) provides information about the integrity of civil structures and infrastructure in the aftermath of an earthquake. However, quantifying the benefits of S2HM information is crucial to justify the investment in S2HM systems. The benefit of S2HM can be computed through the Value of Information (VoI) from Bayesian decision theory, which compares the expected

The paper investigates the potential for a packet switching network for real-time image processing by a Cellular Neural Network (CNN) implemented on a Field-Programmable Gate-Array (FPGA). The implementation of a CNN requires several parameter restrictions with respect to the universal concept. For instance, the number representation and the cloning template are often confined to respectively 8 bi

Wireless access technologies such as UMTS with HSPA extensions, WiMAX, and Flash-OFDM and the convergence towards next generation heterogeneous networks enable the realization of always best connected scenarios. As the resulting heterogeneous networks become easier to access and more reliable to depend on, novel telemedicine services such as vehicular emergency applications emerge. Due to their li

The sphere detector is near-optimal in bit error rates (BER) performance for MIMO detection, but it suffers from the lower detection throughput. In this paper, we propose an improvement to the sub-optimal MIMO detection. The proposed detector can achieve a much higher detection throughput than the sphere detector, with a comparable complexity and a small degradation in BER performance at high sign

Previous research on post-war society emphasized structural violence with subsequent reconciliation processes. Researchers have focused on the importance of narratives, but they have neither highlighted narratives about reconciliation nor analyzed conditions for reconciliation in post-war interviews. This article tries to fill this gap by analyzing the stories told by survivors of the Bosnian war

Shrines and Souls provides a multi-layered contextualization of the article on religious liberty in the Universal Declaration of Human Rights (Article 18), which was propounded by the United Nations General Assembly on December 10, 1948. It shows how the framers of the Declaration decided to break with some of the conventional ways of framing religious liberty in international law, by foregroundin

Surface temperature in internal combustion engines is of high interest when studying heat losses. Two approaches for retrieving the surface temperatures are thermocouples and Laser Induced Phosphorescence, LIP. This study aims to analyze LIP as a technique for measuring surface temperature in internal combustion engines. The motivation for this study is the need for accurate surface temperatures w

There are various ways to classify asthma control; however, no classification is universally accepted. This retrospective analysis compared asthma control as assessed by the Asthma Control Questionnaire (5-item version; ACQ-5), Global Initiative for Asthma (GINA) or Gaining Optimal Asthma Control (GOAL) study criteria. Pooled data at the final study week (n=8,188) from three budesonide/formoterol

Antibody microarray is a novel technology that will allow us to efficiently perform global proteome analysis. Performing rapid and multiplexed analysis on complex proteomes, such as human serum, targeting also low-abundant analytes will, however, place high demands upon the microarray design with respect to logistics, specificity and sensitivity. In this study, we have shown that non-purified affi

The nature of scientific research and the development of scientific software have similarities with processes that follow the agile manifesto: responsiveness to change and collaboration are of the utmost importance. But how well do current scientific software development processes match the practices found in agile development methods, and what are the effects of using agile practices in such proc