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Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia

Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML cells aberrantly express the lymphoid surface protein SLAMF6 (signaling lymphocyte activation molecule family member 6). Knockout of SLAMF6 in AM

Hydraulic force is a novel mechanism of diastolic function which may contribute to decreased diastolic filling in HFpEF and facilitate filling in HFrEF

BACKGROUND: A hydraulic force generated by blood moving the atrio-ventricular plane is a novel mechanism of diastolic function. The direction and magnitude of the force is dependent on the geometrical relationship between the left atrium and ventricle and is measured as the short-axis atrio-ventricular area difference (AVAD). In short, the net hydraulic force acts from a larger area towards a smal

Extracellular-Matrix-Reinforced Bioinks for 3D Bioprinting Human Tissue

Recent advances in 3D bioprinting allow for generating intricate structures with dimensions relevant for human tissue, but suitable bioinks for producing translationally relevant tissue with complex geometries remain unidentified. Here, a tissue-specific hybrid bioink is described, composed of a natural polymer, alginate, reinforced with extracellular matrix derived from decellularized tissue (rEC

A saturated map of common genetic variants associated with human height

Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated wit

Mapping disease-environment connections reported in scientific literature at scale with EasyNER

Climate change and connected environmental disruptions have a large negativeeffect on the health of humans and other species. Improved understanding ofknown links in the environment-disease nexus as well as knowledge gaps isessential to prepare for and mitigate this escalating threat. However, knowledgefragments are scattered across millions of scientific articles making informationsynthesis too c

From workplace to atmosphere – air at the centre of Aerosols’ annual meeting

From workplace to atmosphere – air at the centre of Aerosols’ annual meeting Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies

https://www.plog.lth.se/article/from-workplace-to-atmosphere-air-at-the-centre-of-aerosols-annual-meeting-1/ - 2026-05-25

Oberg 2011 being interdisciplinary

Being Interdisciplinary 12 Being i nterdisciplinary When I started to write this book, I called it “ The Beginners Guide to Interdisciplinary Studies ” . 1 But calling it a guidebook suggests that it is possible to guide the newcomer through the territory. The crux of interdis- ciplinary work is that you enter an unknown territory that requires a protean sensibility. Rather than a compilation of g

https://www.cec.lu.se/sites/cec.lu.se/files/oberg_2011_being_interdisciplinary.pdf - 2026-05-26

Book of abstracts mtc15

5158-456745512-1.pdf MASTER’S THESIS CONFERENCE GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Book of abstracts June 8 2015 FOURTH ANNUAL http://tinyurl.com/Mconf2015 http://tinyurl.com/Mconf2015 http://tinyurl.com/Mconf2015 SECTION 1 Rethinking Current Tools Ludovico Rella Global Studies, Department of Political Science “Transnational Political Regulation of Bitcoin: Virtual Curren

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/book_of_abstracts_mtc15.pdf - 2026-05-26

2021. D€ Syllabus (draft)

2021. D€ syllabus (draft) Doctoral School Agenda 2030 Digital Monies for a Sustainable Future (Fall 2021) The syllabus is preliminary and subject to changes till the course’s start. The course is taught mainly online, but ends with a one-and-a-half physical workshop at Lund University. For administrative matters, contact Charlina Lunvald (charlina.lunvald@fek.lu.se). # Session Required readings Se

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/2021-06/2021.%20D%E2%82%AC%20syllabus%20(draft).pdf - 2026-05-26

Utilizing artificial intelligence and medical experts to identify predictors for common diagnoses in dyspneic adults: A cross-sectional study of consecutive emergency department patients from Southern Sweden

Objective Half of all adult emergency department (ED) visits with a complaint of dyspnea involve acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), or pneumonia, which are often misdiagnosed. We aimed to create an artificial intelligence (AI) diagnostic decision support tool to detect patients with AHF, eCOPD, and pneumonia among dyspneic adults at the beginn

Food-Related Gram-Positive Bacteria: Enterotoxin A Expression in Staphylococcus aureus and a New Regulation Mechanism in Lactococcus lactis

Staphylococcal enterotoxin A (SEA) is the most common enterotoxin found in outbreaks of staphylococcal food poisoning (SFP). Based on the amount of SEA produced, S. aureus strains were divided into two main groups, high- and low-SEA-producing strains. The differences in the amounts of SEA formed were found to be associated with the levels of expression of the sea gene and the bacteriophage version