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Chronic myeloid leukemia (CML) stem cells appear resistant to tyrosine kinase inhibitors (TKIs) in vitro, but their impact and drug sensitivity in vivo has not been systematically assessed. We prospectively analyzed the proportion of Philadelphia chromosome-positive leukemic stem cells (LSCs, Ph+CD34+CD38=) and progenitor cells (LPCs, Ph+CD34+CD38+) from 46 newly diagnosed CML patients both at the

BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy

Objective: Classification criteria for early-stage symptomatic knee osteoarthritis (EsSKOA) should discriminate individuals with EsSKOA from those with other causes of knee symptoms. We sought to identify conditions in the differential diagnosis of EsSKOA in adults with knee symptoms. Design: We conducted an online survey of clinicians. Those consulting monthly on at least five people with undiagn

BACKGROUND: Selective glomerular hypofiltration syndrome (SGHS), formerly shrunken pore syndrome, an emerging marker of glomerular dysfunction, is associated with worsened prognosis in cardiovascular disease, but its role in kidney failure remains underexplored. Osteopontin (OPN) is associated with worsening kidney function and prognosis in chronic kidney disease.PURPOSE: To explore if increased l

Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a

Information for current students On this page you find information for current students, based on "frequently asked questions".  If you cannot find the information that you are looking for here, please have a look at the following webpages at Lund University. Lund University wepage for new students Lund University webpage for current students Lund University Student Life  New LUMES student? See mo

https://www.lumes.lu.se/current-students - 2026-05-29

Master’s Dissertation Structural Mechanics HENRIK DANIELSSON STRENGTH TESTS OF GLULAM BEAMS WITH QUADRATIC HOLES - TEST REPORT Copyright © 2008 by Structural Mechanics, LTH, Sweden. Printed by KFS i Lund AB, Lund, Sweden, March 2008. For information, address: Division of Structural Mechanics, LTH, Lund University, Box 118, SE-221 00 Lund, Sweden. Homepage: http://www.byggmek.lth.se Structural Mech

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm7000/web7153.pdf - 2026-05-28

M 7767:1‐4  Landskap:  Småland    Upptecknat av:  Blenda Andersson  Härad:   Allbo    Adress:    Skörda, Vislanda sn  Socken:  Vislanda    Berättat av:    ‐‐‐‐  Uppteckningsår:    1941    Född år 1880 i Vislanda    Slåttrahjälpe (HC 7, Etn I:16)  (Självbiografi)Då far hade slått upp på maden, brukade Stina i L Madhem komma och be om  slåttrahjälpe. Stina, som var änka, hade ett dagsverkstorp under

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/levnadsminne/Blenda_A/M_7767_s_1-4.pdf - 2026-05-28

HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 45, 2019/20, Nr 4, 2019-12-04 Det lilla vi får i pappersform finns i pärmar, som numer förvaras i mitt rum. Jag följer i möjligaste mån de länkar jag lägger in – slå larm om de inte fungerar! DISPUTATIONER Avhandlingar från andra institutioner står på en hylla i korridoren på plan 3. Du är välkommen att bläddra i dem, men de ska ställas ti

https://www.hist.lu.se/fileadmin/user_upload/historiska/hist/hilma/HILMA_2019-12-04.pdf - 2026-05-28

Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, CH, JB Nr: 01/25 2025-01-31 Nytt år, nya möjligheter Styrelsen har för 2025 tagit fram en verksamhetsplan med fem fokusområden: lön, pension, renoveringar, synlighet och medlemsvård. Dessa kommer vi att ge lite extra glöd och fokus i år! Håll ögonen öppna för kommande

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0125.pdf - 2026-05-29

In mitosis, transcription factors (TFs) and RNA polymerase disperse across the cytoplasm leading to transcriptional silencing, but some TFs are retained on condensed chromatin and mark genomic sites, a mechanism termed mitotic bookmarking. In pluripotent and differentiated cells this mechanism is important for pluripotency maintenance, cell reprogramming and lineage inheritance. However, the role

Popular Abstract in English Cancer diagnostics is an increasingly important task in the modern world due to an increasing cancer incidence and because diagnostics and treatment are given higher priority. There are many requirements to a diagnostic system. First of all it is important to provide an accurate diagnosis to be able to choose the right treatment. In addition, it is preferable that the mOptical coherence tomography (OCT) is a non-invasive optical imaging technique providing approximately 10 micrometer resolution of tissue in vivo. Within ophthalmology, OCT has already proven its value and is routinely used for diagnosing retinal diseases. In many other areas the potential of OCT is explored worldwide, while the technique itself is further developed with improved imaging speed, re

Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. Adipocyte insulin sensitivity, adipose tissue’s ability to expand, and accumulation of subcutaneous rather than visc

Some 4 billion years ago, nature began the experiment that led to you, that bird on the branch, that branch, and everything else which is alive that you see around you. The generating process of all this splendid life is, of course, evolution. Evolution works not only on the macroscopic scale (think eyes, muscles, wings) but also on the molecular scale (think molecular antennas, nanoscale muscles,The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design

The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. If the optic nerve is transected (ONT), adult RGCs die by a form of cell death called apoptosis, and a general hypothesis is that neurotrophic factors can support the survival of injured neurons.With the intention to The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. If the optic nerve is transected (ONT), adult RGCs die by a form of cell death called apoptosis, and a general hypothesis is that neurotrophic factors can support the survival of injured neurons. With the intention to

Knäleden är kroppens största led och är påtagligt komplicerad. Den utsätts dagligen för stora krafter vid såväl böj och vridrörelser som stötkrafter vid stegisättning. För att den skall fungera optimalt måste flera olika komponenter samverka. Brosket som bekläder benändarna bidrar med stötdämpning och ger en mycket låg friktion vid rörelse. Flera olika ligament och muskler som löper över leden bid

The purpose of this paper is to conduct an analysis of how the Code of Ethics has been used by FAR as a strategy in the history of the professionalization project of Swedish auditors from 1923-1994. Acknowledging the differences between professional development in the Anglo-Saxon countries and Continental Europe, the study contributes to nuance the theory of profession and deepen our knowledge of The paper presents an analysis of context within which FAR, the Swedish professional association representing accountants has developed and revised the Code of Ethics from 1923 to 1995. The purpose is to enhance our understanding of the choices made as to what ethical rules were verbalized or codified and the motivations behind the codification. Building on Birkett and Evans’ (2005) model for orga

Reaching intended effects of the covid-19 pandemic vaccination is dependent on both coverage rates and time. Without vaccine mandates in Sweden, communication strategists have become essential to succeed. Vaccine hesitancy is complex with reasons differing on an individual level. This makes mass communication suboptimal, but also mainly what is used due to practical reasons. Consequently, understa

The world has been affected by a pandemic virus called SARS-CoV-2 and caused a high level of deaths. Does the level of relative humidity have an effect on the spread? Different levels of the relative humidity has different affection on humans from a medical aspect. Is there an optimal level of the relative humidity? In this report there is a study on how the level of relative humidity indoor affec

The thesis examines the portrayal of the divine in the works of Jalāl al-Dīn Muḥammad Rūmī and Walt Whitman, specifically through the Masnavi and Leaves of Grass. Thereafter, the study conducts a comparative analysis between Whitman and Rumi’s perception of the divine. The result from the study finds that Rumi’s God is a God integrated into the whole of existence, bound by a mutual sense of love