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Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells.

Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i

HLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus.

AIMS: To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS: During 2003-2004, women undergoing a 75g oral glucose tolerance test (OGTT) during pregnancy were invited to participate in the Mamma Study. Cut-off leve

Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.

The functions of retinoic acid (RA), a potent morphogen with crucial roles in embryogenesis including developmental hematopoiesis, have not been thoroughly investigated in the human setting. Using an in vitro model of human hematopoietic development, we evaluated the effects of RA signaling on the development of blood and on generated hematopoietic progenitors. Decreased RA signaling increases the

Prostate-specific antigen levels at age 60 and lifetime risk of lethal prostate cancer

INTRODUCTION: We investigated the natural history of the relationship between PSA at age 60 and lifetime risk of prostate cancer death in an unscreened cohort followed for 40 years, the Malmö Preventive Project. We also investigated whether percent free PSA could risk-stratify men with low PSAs.METHODS: The cohort included 1162 men aged 58-62 at blood draw in 1981-82, with 1151 deaths by December

Carbon subsurface traffic jam as driver for methane oxidation activity and selectivity on palladium surfaces

Separating how surface and subsurface species affect catalytic function is a challenging task in heterogeneous catalysis, particularly when deposition and segregation take place at reaction conditions. Here, we report on an operando approach to establish surface/subsurface/function correlations. Using temperature modulations we oscillate carbon deposition and segregation over a Pd catalyst. Cataly

Prostate cancer diagnostics: evolution over 30 years and the impact of education level – a prospective population-based study

Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new

Sparse optimization of two-dimensional terahertz spectroscopy

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

Co-adsorption of p-mercaptobenzoic acid on silver nanoparticles enhances the plasmon-mediated coupling reaction of p-ethynylaniline

The enhancement of the electromagnetic field elicited by localized surface plasmon resonance (LSPR) is conducive to the generation of charge carriers, which have an important effect in driving many kinds of chemical reactions. Nonetheless, the short lifespan of charge carriers generated by plasmon (typically femtoseconds to nanoseconds) limits their effectiveness in promoting chemical reactions. H

Insulin levels at 18–20 gestational weeks in pregnant women with obesity are associated with newborn abdominal fat deposition and DNA methylation in cord blood

We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) study. Fasting maternal insulin at 18-20gw was associated with abdominal/total fat mass ratio in newborns inde

Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment : Results from the TTM2 trial

AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and

High Plasma sRAGE (Soluble Receptor for Advanced Glycation End Products) Is Associated With Slower Carotid Intima-Media Thickness Progression and Lower Risk for First-Time Coronary Events and Mortality

Objective- RAGE (receptor for advanced glycation end products) and EMMPRIN (extracellular matrix metalloproteinase inducer) are immune receptors for proinflammatory mediators. These receptors can also be found in a soluble form in the circulation. Soluble RAGE (sRAGE) has shown atheroprotective properties in animal studies, possibly by acting as a decoy receptor for its ligands. Whether sEMMPRIN (

EUFJE-Lund 2023 Conference Materials And Presentations

Climate Emergency: Law, Policy, and Adjudication in the EU 9-10 May 2023, Lund 1 Conference Summary The conference ‘Climate Emergency: Law, Policy, and Adjudication in the EU’ was held in Lund on 9-10 May 2023, organized co-jointly by the EU Forum of Judges for the Environment (EUFJE) and Lund University with the support of the Lund Centre for European Studies (CFE) and the Association of Foreign

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2023-06/EUFJE-Lund%202023%20Conference%20Materials%20and%20Presentations.pdf - 2026-05-30

Arbetsordning För N-fak Och Delegationer Till Dekanen 2026 ENG

Arbetsordning och delegationer COVER PAGE: GUIDANCE DOCUMENTS Rules of Procedure for the Faculty of Science and the Faculty Board’s delegations to the Dean Type of policy document: Guidelines Definition of the type of policy document: Sets out how someone must or should act within the area covered by the guidelines. A ‘must’ rule must be followed, whilst a ‘should’ rule is more in the nature of a

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2026-03/Arbetsordning%20fo%CC%88r%20N-fak%20och%20delegationer%20till%20dekanen_2026_ENG.pdf - 2026-05-30

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[Uppsala stadga 1344 – DS 3864 ; SDHK 5076] Wi Magnus med Gvdz Naath, Konunger Swerikis, Norikis oc Skane, hawm sannelikæ oc ofsannelikæ forstandit, at i warom barndoom waxto vpp manghahanda sithwæniør, flere hartha oc ogagnlikæ, æn gaghnlicæ oc gothæ, med somlikum aalmogha, ooss til myklæ drøwilsæ, oc spakum mannom til manghra handa thungæ. Nu sithæn wi til ara komum, hawm wi bithitt, rathitt oc

https://www.nordlund.lu.se/fileadmin/user_upload/fornsvenska/rtf/Uppsala_1344.rtf - 2026-05-24

CEC i media 2020

Ett axplock av artiklar och andra inslag i medier där forskare knutna till Centrum för miljö- och klimatforskning, CEC, har intervjuats. Så sammanställer FN:s klimatpanel IPCC läget för klimatet(6 december 2020)Markku Rummukainen intervjuades i Dagens Nyheters specialutgåva om klimat och biologisk mångfald, med Greta Thunberg som chefredaktör för dagen, om hur FN:s klimatpanel IPCC fungerar.Artike

https://www.cec.lu.se/sv/nyheter-och-media/cec-i-media/2020 - 2026-05-29

Allman-studieplan-biomedicin-2018-01-01

Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Medicinska fakultetsstyrelsen Allmän studieplan för utbildning på forskarnivå i biomedicin http://www.med.lu.se/utbildning/forskarutbildning (Fastställd av Medicinska fakultetsstyrelsen 2007-05-24) Studieplanen träder ikraft den 1 juli 2007. Reviderad av Forskarutbi

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-biomedicin-2018-01-01.pdf - 2026-05-30