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Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells.

Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i

HLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus.

AIMS: To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS: During 2003-2004, women undergoing a 75g oral glucose tolerance test (OGTT) during pregnancy were invited to participate in the Mamma Study. Cut-off leve

Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.

The functions of retinoic acid (RA), a potent morphogen with crucial roles in embryogenesis including developmental hematopoiesis, have not been thoroughly investigated in the human setting. Using an in vitro model of human hematopoietic development, we evaluated the effects of RA signaling on the development of blood and on generated hematopoietic progenitors. Decreased RA signaling increases the

Prostate-specific antigen levels at age 60 and lifetime risk of lethal prostate cancer

INTRODUCTION: We investigated the natural history of the relationship between PSA at age 60 and lifetime risk of prostate cancer death in an unscreened cohort followed for 40 years, the Malmö Preventive Project. We also investigated whether percent free PSA could risk-stratify men with low PSAs.METHODS: The cohort included 1162 men aged 58-62 at blood draw in 1981-82, with 1151 deaths by December

Carbon subsurface traffic jam as driver for methane oxidation activity and selectivity on palladium surfaces

Separating how surface and subsurface species affect catalytic function is a challenging task in heterogeneous catalysis, particularly when deposition and segregation take place at reaction conditions. Here, we report on an operando approach to establish surface/subsurface/function correlations. Using temperature modulations we oscillate carbon deposition and segregation over a Pd catalyst. Cataly

Prostate cancer diagnostics: evolution over 30 years and the impact of education level – a prospective population-based study

Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new

Sparse optimization of two-dimensional terahertz spectroscopy

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

Co-adsorption of p-mercaptobenzoic acid on silver nanoparticles enhances the plasmon-mediated coupling reaction of p-ethynylaniline

The enhancement of the electromagnetic field elicited by localized surface plasmon resonance (LSPR) is conducive to the generation of charge carriers, which have an important effect in driving many kinds of chemical reactions. Nonetheless, the short lifespan of charge carriers generated by plasmon (typically femtoseconds to nanoseconds) limits their effectiveness in promoting chemical reactions. H

Insulin levels at 18–20 gestational weeks in pregnant women with obesity are associated with newborn abdominal fat deposition and DNA methylation in cord blood

We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) study. Fasting maternal insulin at 18-20gw was associated with abdominal/total fat mass ratio in newborns inde

R02

Att gestalta kön berättelser om scenkonst, makt och medvetna val Gunilla Edemo & Ida Engvoll (red.) Att gestalta kön Berättelser om scenkonst, makt och medvetna val utgiven av teaterhögskolan i stockholm isbn: 978-91-978534-9-1 huvudredaktör: Gunilla Edemo redaktör: Ida Engvoll ansvarig utgivare: Olle Jansson illustrationer: Bianca Kronlöf foto: Christine Ohlsson, Scanpix (www.scanpix.se) grafiska

https://www.thm.lu.se/sites/thm.lu.se/files/r02.pdf - 2026-05-30

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Possible heterogeneity of initial pancreatic islet beta‐cell autoimmunity heralding type 1 diabetes Review-Symposium doi: 10.1111/joim.13648 Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes Åke Lernmark1 , Beena Akolkar2, William Hagopian3, Jeffrey Krischer4, Richard McIndoe5, Marian Rewers6, Jorma Toppari7, Kendra Vehik4, Anette-G. Ziegler8 & The

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/151_2.pdf - 2026-05-30

No title

Examensarbete Avancerad nivå, 30 poäng Självständigt arbete i svenska Ämneslärarutbildningen, inriktning gymnasienivå Problematiska beskrivningar av grammatik En studie om läromedels beskrivningar av grammatik och svensklärares reaktioner på dessa Erik Bandh Kurskod: ÄSVM92 Termin: HT 2018 Handledare: Katarina Lundin Examinator: Marit Julien Abstract Det föreliggande arbetets övergripande syfte va

https://www.uvet.lu.se/fileadmin/user_upload/uvet/lararutbildning/pdf/Forskningsrapporter/Bandh__Erik_Examensarbete_-_Forskningsrapport_i_serie__inte_den_snyggaste_layouten_men_i_af...pdf - 2026-05-28

Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment : Results from the TTM2 trial

AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and

High Plasma sRAGE (Soluble Receptor for Advanced Glycation End Products) Is Associated With Slower Carotid Intima-Media Thickness Progression and Lower Risk for First-Time Coronary Events and Mortality

Objective- RAGE (receptor for advanced glycation end products) and EMMPRIN (extracellular matrix metalloproteinase inducer) are immune receptors for proinflammatory mediators. These receptors can also be found in a soluble form in the circulation. Soluble RAGE (sRAGE) has shown atheroprotective properties in animal studies, possibly by acting as a decoy receptor for its ligands. Whether sEMMPRIN (

Nwpart1

Övningshandledning för fältarbetsvecka på Österlen, NGE501 Åkerman 2017 1 Excursion guide NW Skåne, NGEA 01, 2017 PART 1. Introduction by Associate Prof. Jonas Åkerman Åkerman 2017 2 Cover photo; The NW exposed coastline at Josefinelust with coarse beach boulders (Sw. “malar”), gneiss is the mother rock intersected by various intrusive rocks in dykes. (Photo J. Åkerman) Åkerman 2017 3 Excursion gu

https://www.nateko.lu.se/sites/nateko.lu.se/files/nwpart1.pdf - 2026-05-30

Dataprogram sållar i den genetiska floden – Vetenskap och Hälsa

Dataprogram sållar i den genetiska floden – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Dataprogram sållar i den genetiska floden 2012-05-22 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Med modern teknik för genetisk kartläggning blir floden av genetisk

https://www.vetenskaphalsa.se/dataprogram-sallar-i-den-genetiska-floden/ - 2026-05-29

Bakterieätarna – nytt möjligt vapen mot infektion – Vetenskap och Hälsa

Bakterieätarna – nytt möjligt vapen mot infektion – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Bakterieätarna – nytt möjligt vapen mot infektion 2025-05-21 Bakteriofagerna ser ut som små mån­landare på bakteriens yta. Genom att injicera sin kromosom kan de föröka sig i bakterien. iStock

https://www.vetenskaphalsa.se/fagterapier/ - 2026-05-28