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Aim: In neuroendocrine cells, large dense-core vesicles (LDCVs) undergo highly regulated pre-fusion processes before releasing hormones via membrane fusion. Significant heterogeneity has been found for LDCV population based on the dynamics of membrane fusion. However, how the pre-fusion status impacts the heterogeneity of LDCVs still remains unclear. Hence, we explored pre-fusion determinants of h

BACKGROUND: A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potential inclusion of prostate cancer in the Lynch syndrome tumor spectrum is relevant for family classification, risk estimates and surveillance recommendations in mutation carriers.M

BACKGROUND: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterpart

In recent years it has become increasingly clear that chemical interactions play a fundamental role in aquatic habitats and have far-reaching evolutionary and ecological consequences. A plethora of studies have shown that aquatic organisms from most taxa and functional groups respond to minute concentrations of chemical substances released by other organisms. However, our knowledge of this “chemic

The objective of this study is to increase the knowledge regarding school principals’work situations by examining the associations between various factors and the school principals’assessments of their ability or wish to work until 65 years of age or longer. The 1356 participatingschool principals in this study were aged between 50 and 64 years of age. Individual and workfactors were evaluated in

Habitat loss and population fragmentation pose severe threats to biodiversity and the survival of many species. Population isolation and the decline in effective population size lead to increased genetic drift and inbreeding. In turn, this reduces neutral diversity, and it also affects the genetic load of deleterious mutations. Here, we analyse the effect of such genomic erosion by designing a spa

A common migratory pattern in birds is that northerly breeding populations migrate to more southerly non-breeding sites compared to southerly breeding populations (leap-frog migration). Not only do populations experience differences in migration distances, but also different environmental conditions, which may vary spatiotemporally within their annual cycles, creating distinctive selective pressur

Professor Kontaktinformation E-post: vilhelm [dot] persson [at] jur [dot] lu [dot] se Telefon: +46 46 222 10 09Organisation Juridiska institutionen Rumsnummer: 510 Hämtställe: 56 WebbplatsVilhelm Perssons profil i Lunds universitets forskningsportalAndra roller Forskare Mänskliga rättigheter Profilområdesmedlem LU profilområde: Mänskliga rättigheter Forskare Offentlig rätt Forskare Health Law Doce

https://www.jur.lu.se/vilhelm-persson - 2026-05-27

Psykologiska rapporter från Lund Volym 6, Nr. 1, 2013 Åsikter och engagemang i samhällsfrågor Resultat från en webbundersökning Emma A. Bäck, Hanna Bäck, Henry Montgomery och Felix Funck Institutionen för psykologi, Lunds universitet Psykologiska rapporter från Lund Redaktör: Magnus Lindgren ISSN 1404-8124 Åsikter och engagemang i samhällsfrågor – Bäck, Bäck, Montgomery & Funck 2 Åsikter och engag

https://www.psy.lu.se/sites/psy.lu.se/files/popularvetenskaplig.rapport_v4.pdf - 2026-05-28

Many species up- or downregulate their resting metabolic rate (RMR) when they encounter favourable or unfavourable feeding conditions, respectively. This is thought to promote faster growth when food is abundant and conserve energy reserves when food is scarce. The time it takes to express metabolic plasticity remain little studied. Here, we develop a conceptual model showing how rapid or slow met

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/levnadsminne/M_6710_s_1-34.pdf - 2026-05-25

Handbok för systemägare och systemförvaltare vid LU feb 22 Handbok i systemförvaltning FÖR SYSTEMÄGARE OCH SYSTEMFÖRVALTARE | 2022-02-04 BIRGITTA LASTOW 1 Handbok för systemägare och systemförvaltare vid LU Versionshistorik 1.0 2021-02-04 Inför workshop med systemägare/systemförvaltare 2021-02-16 1.1 2022-02-04 Reviderad i förhållande till handbok för IT-SF/IT-SÄ. Tillägg kap 3 Arbetsgrupp: • Kari

https://www.staff.lu.se/sites/staff.lu.se/files/2022-02/Handbok%20f%C3%B6r%20system%C3%A4gare%20och%20systemf%C3%B6rvaltare%20vid%20LU%20feb%2022.pdf - 2026-05-28

Rapport från ”the Big Apple” Rapport från ”the Big Apple” – om engagemang, sociala medier och volontärarbete Malin Stedt Gustavsson & Anna Rohlin Larsson 2 Inledning Genom Sacos fackliga stipendiefond fick vi möjligheten att åka till New York i december 2009. Vi stannade i lite drygt en vecka och siktade in oss på att få träffa så många olika organisationer som arbetar med frivilligarbete, engagem

https://www.saco.se/globalassets/bilder-video-och-dokument/om-saco/sacos-fackliga-stipendiefond/2009_engagemang-sociala-medier-volontararbete-usa-arl-msg.pdf - 2026-05-25

We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, w

Background: Evolutionary processes can cause strong spatial genetic signatures, such as local loss of genetic diversity, or conflicting histories from mitochondrial versus nuclear markers. Investigating these genetic patterns is important, as they may reveal obscured processes and players. The maternally inherited bacterium Wolbachia is among the most widespread symbionts in insects. Wolbachia typ

The 2011 UN Guiding Principles on Business and Human Rights (UNGPs) introduced human rights due diligence (HRDD) as a societal expectation to businesses to implement a new kind of due diligence risk management process to ‘know and show’ they respect human rights. Ten years later, mandatory human rights due diligence (mHRDD) legislation imposing a legal duty to carry out HRDD has become mainstream

I juli 2016 introducerades lagen om tillfälliga begränsningar av möjligheten att få uppehållstillstånd i Sverige (den tillfälliga lagen). Ikraftträdandet av den tillfälliga lagen innebar att rätten till familjeåterförening för alternativt skyddsbehövande begränsades avsevärt. Enligt 7§ den tillfälliga lagen exkluderades alternativt skyddsbehövande från rätten att återförenas med sin familj under dIn July 2016, the Law on temporary limitations to the possibility of being granted residence permit in Sweden (the Temporary Law) came into force. The Temporary Law implied a sharp turn in Swedish asylum legislation. The right to family reunification, which previously had been granted subsidiary protection beneficiaries and refugees on a similar basis, was suddenly heavily restricted for beneficia